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HT Experiment :

Experiment Id  GSE201520 Name  Whole transcriptome RNAseq analysis of germ cells in Inhba and Inha fetal testis
Experiment Type  RNA-Seq Study Type  WT vs. Mutant
Source  GEO Curation Date  2024-06-03
description  We performed bulk RNA-Seq on male fetal germ cells isolated from E13.5 and E15.5 testes from activin A-deficient mice (Inhba KO), and from E13.5 testes from mice with greater activin A bioactivity (Inha KO). The aim of this experiment was to determine how chronic altered activin A bioactivity altered the germline transcriptome. Germ cells were isolated from embryonic E13.5 and E15.5 Inhba x Oct4-Gfp WT and KO testes, and E13.5 Inha x Oct4-Gfp WT and KO testes via FACS. Cells were collected from n=3-4 (Inhba) and n=2 (littermate pairs; Inha) animals/age/genotype.
  • variables:
  • bulk RNA-seq,
  • developmental stage,
  • genotype

1 Publications

Trail: HTExperiment

38 Samples

Trail: HTExperiment