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HT Experiment :

Experiment Id  GSE195743 Name  MTG8 interacts with LHX6 to specify cortical interneuron subtype identity
Experiment Type  RNA-Seq Study Type  WT vs. Mutant
Source  GEO Curation Date  2024-06-13
description  In the study we compared migrating embryonic cortical interneurons from control mouse embryos and ones carryng homozygous deletions of either Mtg8 or Lhx6. The aim was to identify genes that are co-regulated by LHX6 and MTG8. RNA was isolated from fluorescent cells that had been sorted from control and mutant embryonic cortices. The cDNA was used to prepare libraries using the Nextera XT kit (Illumina). These were run on a NextSeq 500 sequencer (lllumina). Raw sequence data were adapter and quality trimmed (fastp v0.20.1), aligned to the genome with STAR (v2.7b) and reads per transcript determined with FeatureCounts (v1.6.4).
  • variables:
  • bulk RNA-seq,
  • genotype

1 Publications

Trail: HTExperiment

15 Samples

Trail: HTExperiment