| Experiment Id | GSE153187 | Name | The role of Itgb1 in islet development |
| Experiment Type | RNA-Seq | Study Type | WT vs. Mutant |
| Source | GEO | Curation Date | 2024-06-21 |
| description | Pancreatic development requires appropriate environmental cues, in which ECM-Integrin signaling plays a central role in the process. Specifically, we investigated how ECM-Integrin signaling in Ngn3+ cell (endocrine progenitors) regulates islet architecture and functions. Here we showed disruption of ECM-Integrin signaling affects beta cell functional maturation and potential non-autonomous regulation around islets. Four biological replicates were analyzed for wildtype and Itgb1 mutant |
