Experiment Id | GSE244477 | Name | Gene expression profile at the single cell level of Gatad2b WT, Het and KO E16.5 embryos |
Experiment Type | RNA-Seq | Study Type | WT vs. Mutant |
Source | GEO | Curation Date | 2024-06-24 |
description | We performed single-cell RNA sequencing (scRNA-seq) on cortical samples obtained fromGatad2bstop/+ and WT littermates at a single embryonic time point (E16.5) in order to explore underlying mechanisms of Gatad2b function. We also generated Gatad2bstop/stop scRNA-seq data to identify dosage sensitive targets of Gatad2b E16.5 whole cortices were isolated and used fresh for scRNAseq. 3 embryos of WT, 3 embryos of KO and 4 embryos of Het genotypes were used. |