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HT Experiment :

Experiment Id  GSE84305 Name  FACS-sorted Six2-positive nephron progenitor cells at embryonic day 15.5: wildtype (WT) vs. conditional HDAC1&2-null (MUT)
Experiment Type  transcription profiling by array Study Type  WT vs. Mutant
Source  GEO Curation Date  2024-07-09
description  Transcriptional profiling of FACS-sorted Six2-positive nephron progenitor cells from Six2CreEGFP mice without (WT) or with (MUT) homozygously floxed HDAC1 and HDAC2 alleles at the age of embryonic day 15.5. This experiment aimed to uncover the genome-wide alternation in gene expression resulting from the removal of HDAC1&2 in the nephron progenitor population and successive changes to the series of events in kidney development. Two-condition experiment, WT vs. MUT cells. Biological replicates: 4 WTs and 4 MUTs.
  • variables:
  • genotype

1 Publications

Trail: HTExperiment

8 Samples

Trail: HTExperiment