Experiment Id | GSE191077 | Name | Retinal pigment epithelium-specific CLIC4 mutant is a mouse model of dry age-related macular degeneration |
Experiment Type | RNA-Seq | Study Type | WT vs. Mutant |
Source | GEO | Curation Date | 2022-03-02 |
description | Purpose: Bulk RNA-seq was perform to profile changes in 3-month-old mouse RPE cells caused by CLIC4 deficinecy RNAs of RPE cells isolated from 3-month-old knokcout (KO), Control (Ctrl), and CreCtrl mice followed by deep sequencing using Illumina NovaSeq6000 sequencer with pair-end 50 cycles. We use two pairs (KO vs Ctrl), three pairs (KO vs. WT), and two pairs (KO vs. Cre-Ctrl) |