| Experiment Id | GSE200842 | Name | Transcriptomic analysis of injured and uninjured knee joints from Trem2 KO mice [bulk RNA-seq] |
| Experiment Type | RNA-Seq | Study Type | WT vs. Mutant |
| Source | GEO | Curation Date | 2023-06-15 |
| description | Trem2 is a single-pass transmembrane receptor of the immunoglobulin superfamily and is primarily expressed in myeloid cells. Cells from injured and uninjured knee joints of wildtype C57BL/6 mice and Trem2 KO mice were sequenced to determine if Trem2 plays a role in macrophage differentiation or function after joint injury. Right knee joints of 10-week-old C57BL/6 and Trem2 KO mice were injured using a tibial compression injury model. Uninjured and 7-day post-injury joints were collected and cells were analyzed using bulk RNA-seq. |
