| Experiment Id | E-ERAD-433 | Name | RNA seq on olfactory epithelium cryosections |
| Experiment Type | RNA-Seq | Study Type | Baseline |
| Source | ArrayExpress | Curation Date | 2017-07-05 |
| description | Olfactory sensory neurons (OSNs) expressing the same olfactory receptor (OR) are randomly dispersed within the same olfactory epithelial zone. To date, between 4 and 12 zones have been defined based on OR expression by in-situ hybridization studies. However, the total number of zones, their organisation, molecular identity, and their distribution across the dorsal-ventral, anterior-posterior and lateral-medial axes are still unknown. To address these questions we propose to perform RNA-seq on sequential cryosections along the dorsal-ventral and anterior-posterior axes. This will provide a spatial dimension to the quantitative data we already have on the number of each neuron type in the entire epithelium. We aim to use this as preliminary data for a grant application to completely resolve the 3D organisation of the olfactory epithelium at a cellular level. This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/ |
