Experiment Id | E-MTAB-8643 | Name | Effects of increased intracellular calcium and overnutrition on pancreatic beta cell transcriptome |
Experiment Type | RNA-Seq | Study Type | WT vs. Mutant |
Source | ArrayExpress | Curation Date | 2024-04-05 |
description | To determine the individual and combined effects of excitotoxicity and overnutrition on beta-cell gene expression, we analyzed the impact of a high fat diet (HFD) on wild type C57Bl/6J and Abcc8 knockout mice of different sexes. We collected 31 bulk RNA-Seq datasets that originated from FACS-purified pancreatic beta-cells that differed by genotype, diet, and sex. |