Experiment Id | GSE196446 | Name | Dyrk1a dosage effects on the transcriptome of embryonic hearts from the Dp1Tyb mouse model of Down syndrome using scRNAseq |
Experiment Type | RNA-Seq | Study Type | WT vs. Mutant |
Source | GEO | Curation Date | 2024-06-24 |
description | We performed single cell RNAseq on whole hearts from E13.5 Dp1Tyb embryos and from wild-type littermates, as well as hearts from E13.5 Dp1TybDyrk1a+/+/- embryos and wild-type littermates. We identified 14 clusters which were assigned to individual cell types based on expression of marker genes. Single cell RNAseq analysis of 1 E13.5 Dp1Tyb heart, 3 Dp1TybDyrk1a+/+/- embryonic hearts and 3 wild-type embryonic hearts. |