| Experiment Id | GSE121598 | Name | Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity [scRNA-seq] |
| Experiment Type | RNA-Seq | Study Type | WT vs. Mutant |
| Source | GEO | Curation Date | 2024-02-26 |
| description | TH17 cells in autoimmune disease are functionally and metabolically heterogeneous and contain a subset with stemness-associated features but lower anabolic metabolism and a reciprocal subset with higher metabolic activity that supports the transdifferentiation into TH1 cells. Single Cell analysis of TCRb+YFP+ cells from spleen in Rptor deficient and wild type cells. |
