Experiment Id | GSE166444 | Name | Single cell RNA-seq from Trim28 ovary knockout and wildtype mice ovaries and testis |
Experiment Type | RNA-Seq | Study Type | WT vs. Mutant |
Source | GEO | Curation Date | 2023-06-16 |
description | Single cell RNA-seq (scRNA-seq) from Trim28 ovary knockout and wildtype mice ovaries and testis to help elucidate the function of Trim28 in the adult mouse ovaries. The analysis revealed that loss of Trim28 in the adult mouse ovaries lead to a transcriptional reprogramming of the Granulosa cells towards the Sertoli cell fate. Therefore, Trim28 has a function to maintain the adult ovarian cell identity 10X scRNA-seq from Trim KO 8 week mouse ovaries, wildtype 8 week mice ovaries and testis |