Experiment Id | GSE220864 | Name | Reprogramming of rhythmic liver metabolism by intestine clock |
Experiment Type | RNA-Seq | Study Type | WT vs. Mutant |
Source | GEO | Curation Date | 2023-07-31 |
description | To assess potential impact of intestine clock on the rhythmicity of peripheral tissues (liver, kidney and WAT), mice with Bmal1 specifically deleted in the intestine (Bmal1-iKO mice, showing loss of clock function in the intestine) were generated. We collected liver, kidney and WAT samples from Bmal1-iKO and control (Bmal1-flox) mice every 4 hours throughout a light/dark cycle, and subsequently performed transcriptomic analyses. Comparative gene expression profiling analysis of RNA-seq data for Bmal1-iKO and Bmal1-flox mice. |