Experiment Id | E-GEOD-55180 | Series Id | GSE55180 |
Name | UPF2 establishes testis-specific transcriptome enriched in transcripts with shorter 3'UTRs | Experiment Type | RNA-Seq |
Study Type | WT vs. Mutant | Source | ArrayExpress |
Curation Date | 2019-07-15 |
description | This report not only adds a novel mechanism to the current dogma on achieving global shortening of 3'UTRs, but also unveils a novel function of the NMD pathway in establishing tissue-specific transcriptome identity We first generated prospermatogonia-specific Upf2 conditional knockout mice (Ddx4-Cre; Upf2 fl/delta, hereafter called Ddx4-KO) by crossing Ddx4-Cre13 with Upf2 floxed. |