| Experiment Id | GSE222185 | Name | Distinct prefrontal projections oppositely orchestrate social competition and hierarchy |
| Experiment Type | RNA-Seq | Study Type | Baseline |
| Source | GEO | Curation Date | 2024-08-23 |
| description | The medial prefrontal cortex (mPFC) is known as a hub of social hierarchy determination in the brain, Using high throughput single cell transcriptomic analysis and projection-specific genetic manipulation, we discovered that the expression level of Pou3f1 in mPFC-VTA neurons controls social hierarchy. mPFC from social dominants (R1, n=5) and subordinates (R4, n=5) tissue punches were collected and dissected, and the resulting cells were subjected to a 10X Genomics scRNA-seq pipeline |
