| Experiment Id | GSE234256 | Name | Mettl3-mediated m6A Methylation Determines the Size of Endocrine Progenitor Pool and Postnatal Islet Mass [scRNA-seq] |
| Experiment Type | RNA-Seq | Study Type | WT vs. Mutant |
| Source | GEO | Curation Date | 2024-10-18 |
| description | To investigate the role of RNA methyltransferase-like 3 (Mettl3)-mediated m6A modification in pancreatic endocrine differentiation in early embryonic period. We then performed single cell RNA-seq at E15.5 Mettl3pKO pancreas group and E15.5 WT pancreas group We generated transgenic mice lacking Mettl3 specifically in Pdx1+ pancreatic progenitor cells(Mettl3pKO) and dissect E15.5 Mettl3pKO and WT pancreata for single cell RNA-seq. |
