Experiment Id | GSE245339 | Name | Decoding transcriptomic signatures of Cysteine String Protein alpha-mediated synapse maintenance |
Experiment Type | RNA-Seq | Study Type | WT vs. Mutant |
Source | GEO | Curation Date | 2025-01-03 |
description | Cysteine string protein alpha (CSPalpha), encoded by the Dnajc5 gene, is a synaptic vesicle chaperone that is linked to synapse maintenance and neurodegeneration. To investigate the transcriptional changes associated with synapse maintenance, we performed single nucleus transcriptomics on the cortex of CSPalpha knockout (KO) mice and littermate controls. |