| Experiment Id | GSE158283 | Name | Comparative transcriptomic study of skeletal muscles response to muscular dystrophy with myositis |
| Experiment Type | RNA-Seq | Study Type | WT vs. Mutant |
| Source | GEO | Curation Date | 2025-02-04 |
| description | Muscular dystrophy with myositis (mdm) is a severe degenerative muscle disease arising from a spontaneous mutaton at the N2A-PEVK junction of titin protein. The affected mice show a complex disease phenotype, and more organism-wide spread response compared to other myopathies. The project objectives focus on understanding the response pattern of different skeletal muscles to mdm. Examine the transcriptomic response of mdm affected skeletal muscle compared to wildype in the B6C3Fe a/a-Ttnmdm/J +/+ mice |