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HT Experiment :

Experiment Id  GSE260771 Name  Transcriptomics profiling of white adipose tissue of wildtype (WT) and miR-10a knockout (KO) mice fed a normal chow diet (NCD) or high-fat diet (HFD)
Experiment Type  RNA-Seq Study Type  WT vs. Mutant
Source  GEO Curation Date  2025-01-24
description  Adipose tissue remodeling is a dynamic process that involves adipocyte death and turnover. This study investigates the influence of miR-10a-5p on the remodeling of adipose tissue and the metabolic dysfunction prompted by a high-fat diet. Our objective involves examining the impact of a 16-week HFD feeding on both WT mice and miR-10a KO mice, comparing the genes that are differentially regulated based on the dietary intake. White adipose tissue mRNA profiles of WT and miR-10a KO mice fed a NCD or HFD were generated by deep sequencing. Three biological replicates were analyzed for each of conditions.
  • variables:
  • genotype,
  • bulk RNA-seq

1 Publications

Trail: HTExperiment

12 Samples

Trail: HTExperiment