| First Author | Festing MFW | Year | 1987 |
| Journal | Mouse News Lett | Volume | 79 |
| Pages | 22-3 | Mgi Jnum | J:24738 |
| Mgi Id | MGI:72469 | Citation | Festing MFW (1987) BRX5 8N through CBA/J Strains. Mouse News Lett 79:22-3 |
| abstractText | Full text of MNL contribution: BRX58N Inbr 20+. Set of 11 recombinant inbred strains developed by B.A.Taylor from C57BR/cdJ x B10.D2(58N)/Sn. Maint. by Ty. BSC Inbr 57 (Dk). Albino; c. Origin: A stock incorporating BSVS mice was used to found an outbred colony at the ARC Labs. Compton, England. Inbred in 1972 by Dickinson. Sincp7. Maintained by Dk. BSVR Inbr ?. Albino. See BRVR. Maint. by Db. BSVS Inbr ?. Albino. See BRVR. Maint. by Db, Dv. BUB Inbr (J) 122. Albino a, c. Origin: from albinos of unknown ancestry at Brown University, maintained by random mating until 1945. Maintained by J. BXD Inbr 30+. Set of 24 recombinant inbred strains developed by B.A.Taylor from C57BL/6J x DBA/2J. Maint. by Ty. BXH Inbr 30+. Set of 13 recombinant inbred strains developed by B.A.Taylor from C57BL/6J x C3H/HeJ. Maint. by Ty. BXSB Inbr (Mp) 49. Agouti; +. Origin: E.D.Murphy from a cross of C57BL/6J x SB, followed by selection of the satin, non-beige phenotype, followed by b x s mating. Develops spontaneous lupus-like autoimmune syndrome which is strikingly accelerated in the males. This also occurs in F1 hybrids provided BXSB is the male parent, and appears to be due to a Y-linked gene. Maint. by J, Ola. BXVII Inbr ?. No details. Maint. by Cri. CAT Inbr. ?+26 (Lac). Albino c, CatFr. Origin: CatFr arose in strain A. Apparently outcrossed to unknown stock, then inbred by A. Muggleton-Harris. All mice have bilateral cateracts. Maint. by Lac. CBA Agouti: +. Origin: Strong 1920 from a cross of a Bagg albino female and a DBA male. Strain CBA was selected for low mammary tumour incidence, and C3H for a high incidence. CBA is now widely distributed as a general purpose strain. Differences between some substrains are too great to be accounted for by mutation, and must be the result either of substantial residual heterozygosity, or genetic contamination. Three major branches were in existance in 1940, but these had been further subdivided by 1960. CBA/Br Inbr 150. Jackson Lab to Haldane and Gruneberg 1932, to Bonser 1933, to Amsterdam 1948. Carries the H-2q allele in contrast with other substrains which are H-2k. Maint. by A. CBA/Ca and CBA/CaH. Inbr (J) 150+. Jackson Lab to Haldane and Gruneberg 1932, to Carter via Royal Cancer Hospital and British Emp. Cancer Campaign. To Harwell c1953. Maint. by H, J, N, Ola. CBA/H-T6. Inbr (J) N13 F88. Substrain of CBA/H carrying the T(14.15)6Ca translocation introduced by M.F. Lyon by backcrossing for 13 generations, followed by b x s mating. Maint. by H,J. CBA/J Inbr (J) 194. Strong to Andervont 1947 to J 1948. This substrain may have been genetically contaminated prior to 1948. It differs from CBA/Ca. |
