| Primary Identifier | MGI:8293322 | Allele Type | Endonuclease-mediated |
| Attribute String | Hypomorph | Gene | Dmxl1 |
| Strain of Origin | C57BL/6NCrl | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | CRISPR-targeting deleted 4 bp resulting in a transcript with twenty-five missense amino acids after position 1,734, followed by a stop codon. Quantitative real-time PCR analysis of craniofacial tissues at E13.5 showed a ~20% reduction of Dmxl1 expression in heterozygous embryos relative to wild-type controls. |
