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Allele : Gt(ROSA)26Sor<em1(Egln3)Jlob> gene trap ROSA 26, Philippe Soriano; endonuclease-mediated mutation 1, Jose Lopez-Barneo
Primary Identifier  MGI:8319128 Allele Type  Endonuclease-mediated
Attribute String  Conditional ready, Inserted expressed sequence Gene  Gt(ROSA)26Sor
Strain of Origin  FVB/N Is Recombinase  false
Is Wild Type  false
molecularNote  This allele has a loxP-flanked STOP sequence followed by the murine cDNA (GenBank: AJ310548.1) linked to an IRES-GFP reporter element inserted into the locus. Gene expression is driven by the Gt(ROSA)26Sor promoter by capture of the endogenous transcript via a splice acceptor site. When bred to mice expressing cre recombinase, the STOP sequence is deleted, allowing the transcription and expression of EGLN3 and GFP.
  • mutations:
  • Insertion
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