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DO Term : core binding factor acute myeloid leukemia [DOID:0080796] Disease Ontology

Namespace  disease_ontology Obsolete  false
description  An acute myeloid leukemia that is characterized by the presence of t(8;21)(q22;q22) or inv(16)(p13q22)/t(16;16)(p13;q22). These cytogenetic abnormalities result in disruption of the transcription factor CBF, which is a regulator of normal hematopoiesis.
  • synonyms:
  • NCI:C122688
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Disease

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Diseases --> Mouse models

Ontology

Ontology Term --> All ancestors

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Ontology Term --> Direct children

Ontology Term --> Direct parents