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MP Term : abnormal CCL3 level [MP:0031246] Mammalian Phenotype

Namespace  MPheno.ontology Obsolete  false
description  deviation from the normal levels of CCL3 protein, a chemokine that is secreted by a variety of hematopoietic and non-hematopoietic cells upon stimulation and plays a key role in recruiting inflammatory cells (macrophages, lymphocytes, eosinophils and basophils) to sites of injury or inflammation via the CCR1 or CCR5 receptor; it helps promote wound healing by recruiting macrophages to sites of tissue injury; acts as a potent osteoclast activator and induces bone resorption; exerts HIV-suppressive activity; and inhibits hematopoietic stem cell proliferation
  • synonyms:
  • abnormal MIP-1alpha level,
  • abnormal MIP-1 alpha level,
  • abnormal macrophage inflammatory protein 1-alpha level,
  • abnormal C-C motif chemokine 3 level,
  • abnormal MIP1A level,
  • abnormal MIP1-alpha level
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Phenotype

Mammalian phenotypes (MP terms) --> Mouse genes and models

Ontology

Ontology Term --> All ancestors

Ontology Term --> All descendants

Ontology Term --> Direct children

Ontology Term --> Direct parents