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GO Term : IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor [GO:0002416] Gene Ontology

Namespace  biological_process Obsolete  false
description  The process of transporting IgG immunoglobulin, via transcytosis using the FcRn (also known as the neonatal Fc receptor; gene name FCGRT), from apical surface of an epithelial cell to the basolateral surface or vice versa depending on the location. This process is used for uptake of IgG from the milk in the gut in rodents, for transplacental transport of IgG from mother to embryo in humans, and for maintenance of a steady-state distribution of IgG across epithelial boundaries in general in adult mammals.
  • synonyms:
  • IgG antibody transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor,
  • IgG immunoglobulin transcytosis in epithelial cells mediated by neonatal immunoglobulin receptor
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Function

Functions (GO terms and children) --> Mouse features

Functions (GO terms) --> Mouse features

Ontology

Ontology Term --> All ancestors

Ontology Term --> All descendants

Ontology Term --> Direct children

Ontology Term --> Direct parents