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GO Term : symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of RIG-I activity [GO:0039540] Gene Ontology
Namespace  biological_process Obsolete  false
description  A process in which a symbiont interferes with, inhibits or disrupts a cytoplasmic pattern recognition receptor signaling pathway by inhibiting the activity of RIG-1 (also known as DDX58). The cytoplasmic pattern recognition RIG-I recognizes viral RNA synthesized during active viral replication and signals to protect the host against viral infection, for example by inducing the expression of antiviral cytokines.
  • synonyms:
  • suppression by virus of host RIG-I activity,
  • symbiont-mediated suppression of host RIG-I signaling pathway,
  • suppression by virus of host RIG-I signaling pathway,
  • inhibition by virus of host RIG-I,
  • inhibition by virus of host RIG-I signaling,
  • suppression by virus of host RIG-I signalling pathway,
  • inhibition by virus of host DDX58 activity,
  • inhibition of host DDX58/RIG-I by virus,
  • suppression by virus of host DDX58 signaling pathway,
  • suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity,
  • GO:0039538
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