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GO Term : symbiont-mediated suppression of host JAK-STAT cascade via inhibition of host TYK2 activity [GO:0039574] Gene Ontology
Namespace  biological_process Obsolete  false
description  A process in which a symbiont interferes with, inhibits or disrupt a JAK-STAT signal cascade in the host organism by reducing the activity of host TYK2 (tyrosine kinase 2). TYK2 is an intracellular signal-transducing tyrosine kinase involved in numerous cytokines and interferons signaling pathways and transmits the cytokine signal by phosphorylating receptor subunits.
  • synonyms:
  • disruption by virus of host JAK-STAT cascade via inhibition of host TYK2 activity,
  • suppression by virus of host non-receptor tyrosine-protein kinase TYK2 activity,
  • suppression by virus of host JAK-STAT cascade via inhibition of host TYK2 activity,
  • suppression by virus of host TYK2 activity
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