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Publication : Rat MDC family of proteins: sequence analysis, tissue distribution, and expression in prepubertal and adult rat testis.

First Author  Frayne J Year  1997
Journal  Mol Reprod Dev Volume  48
Issue  2 Pages  159-67
PubMed ID  9291465 Mgi Jnum  J:42708
Mgi Id  MGI:1096183 Doi  10.1002/(SICI)1098-2795(199710)48:2<159::AID-MRD3>3.0.CO;2-R
Citation  Frayne J, et al. (1997) Rat MDC family of proteins: sequence analysis, tissue distribution, and expression in prepubertal and adult rat testis. Mol Reprod Dev 48(2):159-67
abstractText  Increasing number of sequence-related cysteine-rich membrane proteins containing metalloproteinase-like and disintegrin-like domains (the MDC protein family) have been identified in mammalian tissues. Here, we report the cloning and sequence analysis of cDNAs encoding several rat orthologues of this protein family, some of which are found to be expressed exclusively in the male reproductive tract, others exhibiting a broader tissue distribution. We also examine their expression in prepubertal an adult rat testis, which, in conjunction with the data on tissue distribution, form a necessary prelude to further studies aimed at establishing their individual functions.
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