Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:1314699 |
Assay Type: |
RNA in situ |
Annotation Date: |
1998-12-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1640617 |
Pattern: |
Regionally restricted |
Stage: |
TS17 |
Assay Id: |
MGI:1314739 |
Age: |
embryonic day 10.5 |
|
Note: |
Transcript distribution is very similar to that of Hoxa13 in Xt;ld double mutants, shown in Fig. 4h. |
Specimen Label: |
not shown |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
Allele |
Name: |
homeobox A13; targeted mutation 1, Jeffrey W Innis |
Allele Type: |
Targeted |
|
|
•
•
•
•
•
|
Allele |
Name: |
homeobox A13; hypodactyly |
Allele Type: |
Spontaneous |
|
|
•
•
•
•
•
|
Allele |
Name: |
homeobox A13; targeted mutation 2, I Pierre Chambon |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
homeobox A cluster; targeted mutation 1, Denis Duboule |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This domain represents the N-terminal region of HoxA13 and other Hox proteins (HoxB13, HoxC13 and HoxD13). HoxA13 is involved in formation of the digital arch of the hands and feet, as well as in correct genital formation []. This domain is found in association with . |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Hoxa13/Hoxa13 |
Background: |
either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6) |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Hoxa13/Hoxa13<+> |
Background: |
either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6) |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Hoxa13/Hoxa13 |
Background: |
involves: 129S2/SvPas * C57BL/6J |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Hoxa13/Hoxa13 |
Background: |
involves: 129S2/SvPas |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Hoxa13/Hoxa13 |
Background: |
either: (involves: 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6J) |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Hoxa13/Hoxa13 |
Background: |
involves: 129S7/SvEvBrd |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Hoxa13/Hoxa13<+> |
Background: |
involves: 129S7/SvEvBrd |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Hoxa13/Hoxa13 |
Background: |
involves: MYA/Hu |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Hoxa13/Hoxa13<+> |
Background: |
B6C3Fe-a/a Hoxa13 Mcoln3/J |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Hoxa13/Hoxa13 |
Background: |
B6C3Fe-a/a Hoxa13 Mcoln3/J |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
Allele |
Name: |
homeobox A13; targeted mutation 1.1, Mario R Capecchi |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
homeobox A13; targeted mutation 1.1, Mark L Kahn |
Allele Type: |
Targeted |
Attribute String: |
Recombinase |
|
•
•
•
•
•
|
Allele |
Name: |
homeobox A13; targeted mutation 1.1, Marie Kmita |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout, Recombinase, Reporter |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Hoxa13/Hoxa13<+> Hoxd13/Hoxd13<+> |
Background: |
either: (involves: 129/Sv * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6) |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Hoxa13/Hoxa13<+> Hoxd13/Hoxd13 |
Background: |
either: (involves: 129/Sv * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6) |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Hoxa13/Hoxa13 Hoxd13/Hoxd13<+> |
Background: |
either: (involves: 129/Sv * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6) |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Hoxa13/Hoxa13 Hoxd13/Hoxd13 |
Background: |
either: (involves: 129/Sv * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6) |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Hoxa13/Hoxa13 Hoxd13/Hoxd13 |
Background: |
involves: 129S2/SvPas |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Hoxa13/Hoxa13 Hoxd13/Hoxd13<+> |
Background: |
involves: 129S2/SvPas |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Hoxa13/Hoxa13<+> Hoxd13/Hoxd13 |
Background: |
involves: 129S2/SvPas |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Neufeld SJ |
Year: |
2014 |
Journal: |
Genetics |
Title: |
Genetic interactions between Shox2 and Hox genes during the regional growth and development of the mouse limb. |
Volume: |
198 |
Issue: |
3 |
Pages: |
1117-26 |
|
•
•
•
•
•
|
Allele |
Name: |
homeobox A13; targeted mutation 1.1, Miguel Torres |
Allele Type: |
Targeted |
Attribute String: |
Inducible, Recombinase |
|
•
•
•
•
•
|
Publication |
First Author: |
Lebert-Ghali CE |
Year: |
2010 |
Journal: |
Exp Hematol |
Title: |
HoxA cluster is haploinsufficient for activity of hematopoietic stem and progenitor cells. |
Volume: |
38 |
Issue: |
11 |
Pages: |
1074-1086.e1-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Berlivet S |
Year: |
2013 |
Journal: |
PLoS Genet |
Title: |
Clustering of tissue-specific sub-TADs accompanies the regulation of HoxA genes in developing limbs. |
Volume: |
9 |
Issue: |
12 |
Pages: |
e1004018 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lebert-Ghali CÉ |
Year: |
2016 |
Journal: |
Blood |
Title: |
Hoxa cluster genes determine the proliferative activity of adult mouse hematopoietic stem and progenitor cells. |
Volume: |
127 |
Issue: |
1 |
Pages: |
87-90 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Hoxa13/Hoxa13<+> |
Background: |
involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6 |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Hoxa13/Hoxa13 |
Background: |
involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6 |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Hoxa13/Hoxa13 |
Background: |
involves: 129S1/Sv * 129X1/SvJ |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Hoxa13/Hoxa13<+> |
Background: |
involves: 129S1/Sv * 129X1/SvJ |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Hoxa13/Hoxa13 |
Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * Swiss Webster |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Hoxa13/Hoxa13 |
Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Hoxa13/Hoxa13<+> |
Background: |
involves: 129S1/Sv * 129X1/SvJ |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Hoxa13/Hoxa13 |
Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Hoxa13/Hoxa13<+> |
Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Hoxa13/Hoxa13<+> |
Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * Swiss Webster |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Hoxa13/Hoxa13<+> |
Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Del(2Hoxd1-Hoxd13)1Ddu/+ Hoxa13/Hoxa13<+> |
Background: |
involves: 129S2/SvPas * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Del(2Hoxd1-Hoxd13)1Ddu/Del(2Hoxd1-Hoxd13)1Ddu Hoxa13/Hoxa13<+> |
Background: |
involves: 129S2/SvPas * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Del(2Hoxd1-Hoxd13)1Ddu/Del(2Hoxd1-Hoxd13)1Ddu Hoxa13/Hoxa13 |
Background: |
involves: 129S2/SvPas * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Hoxa13/Hoxa13 Hoxd13/Hoxd13 |
Background: |
involves: 129S2/SvPas * C57BL/6 * CD-1 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
RNA-Seq |
Study Type: |
Baseline |
Source: |
GEO |
|
•
•
•
•
•
|
Publication |
First Author: |
Vieux-Rochas M |
Year: |
2013 |
Journal: |
Dev Biol |
Title: |
Combined function of HoxA and HoxB clusters in neural crest cells. |
Volume: |
382 |
Issue: |
1 |
Pages: |
293-301 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Gli3/Gli3 Hoxa13/Hoxa13<+> |
Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Gli3/Gli3<+> Hoxa13/Hoxa13<+> |
Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Liang G |
Year: |
2021 |
Journal: |
Dev Cell |
Title: |
De novo generation of macrophage from placenta-derived hemogenic endothelium. |
Volume: |
56 |
Issue: |
14 |
Pages: |
2121-2133.e6 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Del(2Hoxd10-Hoxd13)7Ddu/Del(2Hoxd10-Hoxd13)7Ddu Hoxa/Hoxa<+> Del(6Hoxa)1Ddu/+ Tg(Prrx1-cre)1Cjt/? |
Background: |
involves: 129S2/SvPas * C57BL/6 * SJL |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Del(2Hoxd8-Hoxd13)11Ddu/Del(2Hoxd8-Hoxd13)11Ddu Hoxa/Hoxa<+> Del(6Hoxa)1Ddu/+ Tg(Prrx1-cre)1Cjt/? |
Background: |
involves: 129S2/SvPas * C57BL/6J * SJL/J |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Del(2Hoxd10-Hoxd12)19Ddu/Del(2Hoxd10-Hoxd12)19Ddu Hoxa/Hoxa<+> Del(6Hoxa)1Ddu/+ Tg(Prrx1-cre)1Cjt/? |
Background: |
involves: 129S2/SvPas * C57BL/6J * SJL/J |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Del(2Hoxd9-Hoxd12)20Ddu/Del(2Hoxd9-Hoxd12)20Ddu Hoxa/Hoxa<+> Del(6Hoxa)1Ddu/+ Tg(Prrx1-cre)1Cjt/? |
Background: |
involves: 129S2/SvPas * C57BL/6J * SJL/J |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Del(2Hoxd11-Hoxd13)16Ddu/Del(2Hoxd11-Hoxd13)16Ddu Hoxa/Hoxa<+> Del(6Hoxa)1Ddu/+ Tg(Prrx1-cre)1Cjt/? |
Background: |
involves: 129S2/SvPas * C57BL/6J * SJL/J |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Gli3/Gli3 Hoxa13/Hoxa13<+> |
Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Hoxa13/Hoxa13<+> |
Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Hoxa13/Hoxa13<+> |
Background: |
involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Boulet AM |
Year: |
2004 |
Journal: |
Development |
Title: |
Multiple roles of Hoxa11 and Hoxd11 in the formation of the mammalian forelimb zeugopod. |
Volume: |
131 |
Issue: |
2 |
Pages: |
299-309 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mericskay M |
Year: |
2004 |
Journal: |
Development |
Title: |
Wnt5a is required for proper epithelial-mesenchymal interactions in the uterus. |
Volume: |
131 |
Issue: |
9 |
Pages: |
2061-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Salsi V |
Year: |
2009 |
Journal: |
Mol Cell Biol |
Title: |
HOXD13 binds DNA replication origins to promote origin licensing and is inhibited by geminin. |
Volume: |
29 |
Issue: |
21 |
Pages: |
5775-88 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jerković I |
Year: |
2017 |
Journal: |
PLoS Genet |
Title: |
Genome-Wide Binding of Posterior HOXA/D Transcription Factors Reveals Subgrouping and Association with CTCF. |
Volume: |
13 |
Issue: |
1 |
Pages: |
e1006567 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tarchini B |
Year: |
2006 |
Journal: |
Nature |
Title: |
Regulatory constraints in the evolution of the tetrapod limb anterior-posterior polarity. |
Volume: |
443 |
Issue: |
7114 |
Pages: |
985-8 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Hoxa13/Hoxa13<+> |
Background: |
involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6NTac |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Grier DG |
Year: |
2005 |
Journal: |
J Pathol |
Title: |
The pathophysiology of HOX genes and their role in cancer. |
Volume: |
205 |
Issue: |
2 |
Pages: |
154-71 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
328
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
386
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
286
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
339
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
296
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Di-Poï N |
Year: |
2010 |
Journal: |
Dev Biol |
Title: |
Additive and global functions of HoxA cluster genes in mesoderm derivatives. |
Volume: |
341 |
Issue: |
2 |
Pages: |
488-98 |
|
•
•
•
•
•
|
Publication |
First Author: |
Soshnikova N |
Year: |
2013 |
Journal: |
Dev Biol |
Title: |
Duplications of hox gene clusters and the emergence of vertebrates. |
Volume: |
378 |
Issue: |
2 |
Pages: |
194-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Minoux M |
Year: |
2009 |
Journal: |
Development |
Title: |
Rostral and caudal pharyngeal arches share a common neural crest ground pattern. |
Volume: |
136 |
Issue: |
4 |
Pages: |
637-45 |
|
•
•
•
•
•
|
Publication |
First Author: |
Plein A |
Year: |
2018 |
Journal: |
Nature |
Title: |
Erythro-myeloid progenitors contribute endothelial cells to blood vessels. |
Volume: |
562 |
Issue: |
7726 |
Pages: |
223-228 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
|
•
•
•
•
•
|