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Search results 1 to 100 out of 221 for Eif2ak3

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Category: Publication
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Type Details Score
Publication
17141632 | J:144661
First Author: Zhang W
Year: 2006
Journal: Cell Metab
Title: PERK EIF2AK3 control of pancreatic beta cell differentiation and proliferation is required for postnatal glucose homeostasis.
Volume: 4
Issue: 6
Pages: 491-7
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Publication
23554479 | J:238042
First Author: Lin W
Year: 2013
Journal: J Neurosci
Title: Oligodendrocyte-specific activation of PERK signaling protects mice against experimental autoimmune encephalomyelitis.
Volume: 33
Issue: 14
Pages: 5980-91
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Publication
30137327 | J:267209
First Author: Yuan SH
Year: 2018
Journal: Hum Mol Genet
Title: Tauopathy-associated PERK alleles are functional hypomorphs that increase neuronal vulnerability to ER stress.
Volume: 27
Issue: 22
Pages: 3951-3963
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Publication
10932183 | J:63886
First Author: Delépine M
Year: 2000
Journal: Nat Genet
Title: EIF2AK3, encoding translation initiation factor 2-alpha kinase 3, is mutated in patients with Wolcott-Rallison syndrome.
Volume: 25
Issue: 4
Pages: 406-9
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Publication
22253692 | J:223903
First Author: Stockwell SR
Year: 2012
Journal: PLoS One
Title: Mechanism-based screen for G1/S checkpoint activators identifies a selective activator of EIF2AK3/PERK signalling.
Volume: 7
Issue: 1
Pages: e28568
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Publication
27095827 | J:244664
 
First Author: Musner N
Year: 2016
Journal: ASN Neuro
Title: Perk Ablation Ameliorates Myelination in S63del-Charcot-Marie-Tooth 1B Neuropathy.
Volume: 8
Issue: 2
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Publication
30204503 | J:286663
First Author: Gallot YS
Year: 2019
Journal: FASEB J
Title: PERK regulates skeletal muscle mass and contractile function in adult mice.
Volume: 33
Issue: 2
Pages: 1946-1962
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Publication
19956728 | J:155377
First Author: Gupta S
Year: 2009
Journal: PLoS One
Title: PERK regulates the proliferation and development of insulin-secreting beta-cell tumors in the endocrine pancreas of mice.
Volume: 4
Issue: 11
Pages: e8008
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Publication
24269558 | J:207934
First Author: Lin Y
Year: 2014
Journal: Am J Pathol
Title: PERK activation preserves the viability and function of remyelinating oligodendrocytes in immune-mediated demyelinating diseases.
Volume: 184
Issue: 2
Pages: 507-19
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Publication
35299279 | J:326675
First Author: Chen K
Year: 2022
Journal: Aging Cell
Title: Inhibition of unfolded protein response prevents post-anesthesia neuronal hyperactivity and synapse loss in aged mice.
Volume: 21
Issue: 4
Pages: e13592
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Publication
31680865 | J:332408
 
First Author: Sims SG
Year: 2019
Journal: Front Cell Neurosci
Title: Janus Kinase 1 Is Required for Transcriptional Reprograming of Murine Astrocytes in Response to Endoplasmic Reticulum Stress.
Volume: 13
Pages: 446
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Publication
11997520 | J:76661
First Author: Zhang P
Year: 2002
Journal: Mol Cell Biol
Title: The PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas.
Volume: 22
Issue: 11
Pages: 3864-74
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Publication
32029570 | J:286129
 
First Author: Kato H
Year: 2020
Journal: Life Sci Alliance
Title: ER-resident sensor PERK is essential for mitochondrial thermogenesis in brown adipose tissue.
Volume: 3
Issue: 3
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Publication
24915520 | J:218569
First Author: Wang R
Year: 2014
Journal: PLoS One
Title: Perk gene dosage regulates glucose homeostasis by modulating pancreatic β-cell functions.
Volume: 9
Issue: 6
Pages: e99684
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Publication
17822768 | J:126349
First Author: Gass JN
Year: 2008
Journal: Mol Immunol
Title: The unfolded protein response of B-lymphocytes: PERK-independent development of antibody-secreting cells.
Volume: 45
Issue: 4
Pages: 1035-43
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Publication
27334877 | J:260636
 
First Author: Chen Y
Year: 2016
Journal: Neurobiol Dis
Title: Calcineurin β protects brain after injury by activating the unfolded protein response.
Volume: 94
Pages: 139-56
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Publication
17273557 | J:118037
First Author: Lin W
Year: 2007
Journal: J Clin Invest
Title: The integrated stress response prevents demyelination by protecting oligodendrocytes against immune-mediated damage.
Volume: 117
Issue: 2
Pages: 448-56
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Publication
32768667 | J:306918
First Author: Shimizu T
Year: 2020
Journal: iScience
Title: PERK-Mediated Suppression of microRNAs by Sildenafil Improves Mitochondrial Dysfunction in Heart Failure.
Volume: 23
Issue: 8
Pages: 101410
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Publication
33208886 | J:300235
First Author: Shimizu T
Year: 2020
Journal: Sci Rep
Title: PERK participates in cardiac valve development via fatty acid oxidation and endocardial-mesenchymal transformation.
Volume: 10
Issue: 1
Pages: 20094
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Publication
34583519 | J:341477
First Author: Zhang G
Year: 2021
Journal: Circulation
Title: Integrated Stress Response Couples Mitochondrial Protein Translation With Oxidative Stress Control.
Volume: 144
Issue: 18
Pages: 1500-1515
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Publication
32788341 | J:311705
 
First Author: Hughes DT
Year: 2020
Journal: Sci Signal
Title: Targeting the kinase insert loop of PERK selectively modulates PERK signaling without systemic toxicity in mice.
Volume: 13
Issue: 644
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Publication
27627766 | J:251039
First Author: Zhu S
Year: 2016
Journal: PLoS One
Title: PERK Regulates Working Memory and Protein Synthesis-Dependent Memory Flexibility.
Volume: 11
Issue: 9
Pages: e0162766
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Publication
27993242 | J:239385
First Author: Gannon PJ
Year: 2017
Journal: Am J Pathol
Title: HIV Protease Inhibitors Alter Amyloid Precursor Protein Processing via β-Site Amyloid Precursor Protein Cleaving Enzyme-1 Translational Up-Regulation.
Volume: 187
Issue: 1
Pages: 91-109
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Publication
35401837 | J:338333
First Author: Liu C
Year: 2022
Journal: Theranostics
Title: Endothelial PERK-ATF4-JAG1 axis activated by T-ALL remodels bone marrow vascular niche.
Volume: 12
Issue: 6
Pages: 2894-2907
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Publication
29230015 | J:264499
First Author: Bu Y
Year: 2018
Journal: Nat Cell Biol
Title: A PERK-miR-211 axis suppresses circadian regulators and protein synthesis to promote cancer cell survival.
Volume: 20
Issue: 1
Pages: 104-115
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Publication
16973740 | J:248236
First Author: Zhou J
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response.
Volume: 103
Issue: 39
Pages: 14343-8
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Publication
22915762 | J:215862
First Author: Wang Y
Year: 2012
Journal: Cancer Res
Title: The unfolded protein response induces the angiogenic switch in human tumor cells through the PERK/ATF4 pathway.
Volume: 72
Issue: 20
Pages: 5396-406
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Publication
12610133 | J:201568
First Author: Pavio N
Year: 2003
Journal: J Virol
Title: Protein synthesis and endoplasmic reticulum stress can be modulated by the hepatitis C virus envelope protein E2 through the eukaryotic initiation factor 2alpha kinase PERK.
Volume: 77
Issue: 6
Pages: 3578-85
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Publication
16288713 | J:149195
First Author: Suragani RN
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Interaction of recombinant human eIF2 subunits with eIF2B and eIF2alpha kinases.
Volume: 338
Issue: 4
Pages: 1766-72
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Publication
23667408 | J:201928
 
First Author: Egan PA
Year: 2013
Journal: Open Virol J
Title: Hepatitis C Virus Envelope Protein E1 Binds PERK and Represses the Unfolded Protein Response.
Volume: 7
Pages: 37-40
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Publication
18550523 | J:140265
First Author: Mak BC
Year: 2008
Journal: J Biol Chem
Title: Novel function of PERK as a mediator of force-induced apoptosis.
Volume: 283
Issue: 34
Pages: 23462-72
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Publication
21737679 | J:183036
First Author: Gao N
Year: 2011
Journal: Mol Biol Cell
Title: Mannose-6-phosphate regulates destruction of lipid-linked oligosaccharides.
Volume: 22
Issue: 17
Pages: 2994-3009
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Publication
22705852 | J:205472
First Author: Verfaillie T
Year: 2012
Journal: Cell Death Differ
Title: PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress.
Volume: 19
Issue: 11
Pages: 1880-91
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Publication
25925385 | J:222776
First Author: Carrara M
Year: 2015
Journal: EMBO J
Title: Crystal structures reveal transient PERK luminal domain tetramerization in endoplasmic reticulum stress signaling.
Volume: 34
Issue: 11
Pages: 1589-600
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Publication
29196323 | J:297377
First Author: Sharma V
Year: 2018
Journal: J Neurosci
Title: Local Inhibition of PERK Enhances Memory and Reverses Age-Related Deterioration of Cognitive and Neuronal Properties.
Volume: 38
Issue: 3
Pages: 648-658
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Publication
27141928 | J:259530
First Author: Philippe C
Year: 2016
Journal: Sci Signal
Title: PERK mediates the IRES-dependent translational activation of mRNAs encoding angiogenic growth factors after ischemic stress.
Volume: 9
Issue: 426
Pages: ra44
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Publication
26450683 | J:319347
First Author: Radford H
Year: 2015
Journal: Acta Neuropathol
Title: PERK inhibition prevents tau-mediated neurodegeneration in a mouse model of frontotemporal dementia.
Volume: 130
Issue: 5
Pages: 633-42
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Publication
23071091 | J:192859
First Author: Gao Y
Year: 2012
Journal: Mol Cell Biol
Title: PERK is required in the adult pancreas and is essential for maintenance of glucose homeostasis.
Volume: 32
Issue: 24
Pages: 5129-39
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Publication
21709020 | J:175081
First Author: Avivar-Valderas A
Year: 2011
Journal: Mol Cell Biol
Title: PERK integrates autophagy and oxidative stress responses to promote survival during extracellular matrix detachment.
Volume: 31
Issue: 17
Pages: 3616-29
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Publication
20798685 | J:186981
First Author: Lépine S
Year: 2011
Journal: Cell Death Differ
Title: Sphingosine-1-phosphate phosphohydrolase-1 regulates ER stress-induced autophagy.
Volume: 18
Issue: 2
Pages: 350-61
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Publication
23524851 | J:198373
First Author: Guo C
Year: 2013
Journal: EMBO J
Title: SENP3-mediated deSUMOylation of dynamin-related protein 1 promotes cell death following ischaemia.
Volume: 32
Issue: 11
Pages: 1514-28
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Publication
23921556 | J:200066
First Author: Muñoz JP
Year: 2013
Journal: EMBO J
Title: Mfn2 modulates the UPR and mitochondrial function via repression of PERK.
Volume: 32
Issue: 17
Pages: 2348-61
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Publication
36126165 | J:331950
First Author: Riesenberg BP
Year: 2022
Journal: Cancer Res
Title: Stress-Mediated Attenuation of Translation Undermines T-cell Activity in Cancer.
Volume: 82
Issue: 23
Pages: 4386-4399
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18049481 | J:146385
First Author: Kudo T
Year: 2008
Journal: Cell Death Differ
Title: A molecular chaperone inducer protects neurons from ER stress.
Volume: 15
Issue: 2
Pages: 364-75
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15314157 | J:92781
First Author: Blais JD
Year: 2004
Journal: Mol Cell Biol
Title: Activating transcription factor 4 is translationally regulated by hypoxic stress.
Volume: 24
Issue: 17
Pages: 7469-82
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Publication
29076578 | J:256284
First Author: VerPlank JJS
Year: 2018
Journal: Glia
Title: Impairment of protein degradation and proteasome function in hereditary neuropathies.
Volume: 66
Issue: 2
Pages: 379-395
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Publication
27807175 | J:236772
First Author: Sidoli M
Year: 2016
Journal: J Neurosci
Title: Ablation of Perk in Schwann Cells Improves Myelination in the S63del Charcot-Marie-Tooth 1B Mouse.
Volume: 36
Issue: 44
Pages: 11350-11361
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Publication
28948615 | J:258331
First Author: Zhang M
Year: 2017
Journal: FEBS Lett
Title: NDRG2 acts as a PERK co-factor to facilitate PERK branch and ERS-induced cell death.
Volume: 591
Issue: 21
Pages: 3670-3681
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Publication
29337352 | J:264586
First Author: Zimmermann HR
Year: 2018
Journal: J Neurochem
Title: Genetic removal of eIF2α kinase PERK in mice enables hippocampal L-LTP independent of mTORC1 activity.
Volume: 146
Issue: 2
Pages: 133-144
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Publication
23933749 | J:203865
First Author: Ma T
Year: 2013
Journal: Nat Neurosci
Title: Suppression of eIF2α kinases alleviates Alzheimer's disease-related plasticity and memory deficits.
Volume: 16
Issue: 9
Pages: 1299-305
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Publication
19783659 | J:269837
First Author: Bunpo P
Year: 2009
Journal: J Biol Chem
Title: GCN2 protein kinase is required to activate amino acid deprivation responses in mice treated with the anti-cancer agent L-asparaginase.
Volume: 284
Issue: 47
Pages: 32742-9
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Publication
15911877 | J:99655
First Author: Lin W
Year: 2005
Journal: J Cell Biol
Title: Endoplasmic reticulum stress modulates the response of myelinating oligodendrocytes to the immune cytokine interferon-gamma.
Volume: 169
Issue: 4
Pages: 603-12
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Publication
29718201 | J:265094
First Author: Grande V
Year: 2018
Journal: Hum Mol Genet
Title: PERK inhibition delays neurodegeneration and improves motor function in a mouse model of Marinesco-Sjögren syndrome.
Volume: 27
Issue: 14
Pages: 2477-2489
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Publication
35501370 | J:340415
First Author: Zhang D
Year: 2022
Journal: Nat Cell Biol
Title: A non-canonical cGAS-STING-PERK pathway facilitates the translational program critical for senescence and organ fibrosis.
Volume: 24
Issue: 5
Pages: 766-782
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Publication
21285438 | J:170501
First Author: Nanua S
Year: 2011
Journal: Blood
Title: Activation of the unfolded protein response is associated with impaired granulopoiesis in transgenic mice expressing mutant Elane.
Volume: 117
Issue: 13
Pages: 3539-47
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Publication
33592173 | J:303734
First Author: Latorre-Muro P
Year: 2021
Journal: Cell Metab
Title: A cold-stress-inducible PERK/OGT axis controls TOM70-assisted mitochondrial protein import and cristae formation.
Volume: 33
Issue: 3
Pages: 598-614.e7
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Publication
24481666 | J:207477
First Author: Hussien Y
Year: 2014
Journal: Glia
Title: Genetic inactivation of PERK signaling in mouse oligodendrocytes: normal developmental myelination with increased susceptibility to inflammatory demyelination.
Volume: 62
Issue: 5
Pages: 680-91
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Publication
32661025 | J:294220
First Author: Lei Z
Year: 2020
Journal: J Neurosci
Title: NF-κB Activation Accounts for the Cytoprotective Effects of PERK Activation on Oligodendrocytes during EAE.
Volume: 40
Issue: 33
Pages: 6444-6456
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26627716 | J:228322
First Author: Yu Q
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Type I interferons mediate pancreatic toxicities of PERK inhibition.
Volume: 112
Issue: 50
Pages: 15420-5
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Publication
30553965 | J:272889
First Author: Liu Z
Year: 2019
Journal: Exp Cell Res
Title: PERK is essential for proliferation of intestinal stem cells in mice.
Volume: 375
Issue: 1
Pages: 42-51
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Publication
33500333 | J:322149
 
First Author: Shimizu T
Year: 2021
Journal: Sci Signal
Title: PERK inhibition attenuates vascular remodeling in pulmonary arterial hypertension caused by BMPR2 mutation.
Volume: 14
Issue: 667
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17325203 | J:119826
First Author: Shang J
Year: 2007
Journal: J Cell Biol
Title: Translation attenuation by PERK balances ER glycoprotein synthesis with lipid-linked oligosaccharide flux.
Volume: 176
Issue: 5
Pages: 605-16
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26483256 | J:328974
First Author: Barati MT
Year: 2016
Journal: Cell Stress Chaperones
Title: Differential expression of endoplasmic reticulum stress-response proteins in different renal tubule subtypes of OVE26 diabetic mice.
Volume: 21
Issue: 1
Pages: 155-166
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Publication
34549728 | J:335833
 
First Author: He Z
Year: 2021
Journal: JCI Insight
Title: PERK in POMC neurons connects celastrol with metabolism.
Volume: 6
Issue: 18
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20530744 | J:169638
First Author: Gupta S
Year: 2010
Journal: Diabetes
Title: PERK (EIF2AK3) regulates proinsulin trafficking and quality control in the secretory pathway.
Volume: 59
Issue: 8
Pages: 1937-47
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Publication
24958502 | J:281019
First Author: Liu X
Year: 2014
Journal: Hypertension
Title: Endoplasmic reticulum stress sensor protein kinase R-like endoplasmic reticulum kinase (PERK) protects against pressure overload-induced heart failure and lung remodeling.
Volume: 64
Issue: 4
Pages: 738-44
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Publication
32617517 | J:295192
First Author: Cardoso AC
Year: 2020
Journal: Nat Metab
Title: Mitochondrial Substrate Utilization Regulates Cardiomyocyte Cell Cycle Progression.
Volume: 2
Issue: 2
Pages: 167-178
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12865332 | J:84818
First Author: Li Y
Year: 2003
Journal: Endocrinology
Title: PERK eIF2alpha kinase regulates neonatal growth by controlling the expression of circulating insulin-like growth factor-I derived from the liver.
Volume: 144
Issue: 8
Pages: 3505-13
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Publication
29335505 | J:260150
First Author: Hisanaga S
Year: 2018
Journal: Sci Rep
Title: PERK-mediated translational control is required for collagen secretion in chondrocytes.
Volume: 8
Issue: 1
Pages: 773
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11430819 | J:70005
First Author: Harding HP
Year: 2001
Journal: Mol Cell
Title: Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival.
Volume: 7
Issue: 6
Pages: 1153-63
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Publication
27181404 | J:234016
First Author: Ho Y
Year: 2016
Journal: Am J Pathol
Title: PERK Activation Promotes Medulloblastoma Tumorigenesis by Attenuating Premalignant Granule Cell Precursor Apoptosis.
Volume: 186
Issue: 7
Pages: 1939-51
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Publication
30118681 | J:266458
First Author: Chang TK
Year: 2018
Journal: Mol Cell
Title: Coordination between Two Branches of the Unfolded Protein Response Determines Apoptotic Cell Fate.
Volume: 71
Issue: 4
Pages: 629-636.e5
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Publication
18852460 | J:141100
First Author: Bobrovnikova-Marjon E
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiation.
Volume: 105
Issue: 42
Pages: 16314-9
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17475769 | J:127460
First Author: Mazroui R
Year: 2007
Journal: Mol Biol Cell
Title: Inhibition of the ubiquitin-proteasome system induces stress granule formation.
Volume: 18
Issue: 7
Pages: 2603-18
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20661282 | J:163090
First Author: Yang L
Year: 2010
Journal: PLoS One
Title: A Phos-tag-based approach reveals the extent of physiological endoplasmic reticulum stress.
Volume: 5
Issue: 7
Pages: e11621
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21193559 | J:182887
First Author: Moore CE
Year: 2011
Journal: Mol Endocrinol
Title: PERK activation at low glucose concentration is mediated by SERCA pump inhibition and confers preemptive cytoprotection to pancreatic β-cells.
Volume: 25
Issue: 2
Pages: 315-26
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Publication
23068609 | J:190704
First Author: Gupta S
Year: 2012
Journal: FEBS Lett
Title: NOXA contributes to the sensitivity of PERK-deficient cells to ER stress.
Volume: 586
Issue: 22
Pages: 4023-30
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Publication
25986605 | J:223302
   
First Author: Mendez AS
Year: 2015
Journal: Elife
Title: Endoplasmic reticulum stress-independent activation of unfolded protein response kinases by a small molecule ATP-mimic.
Volume: 4
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26753564 | J:316517
 
First Author: Vandewynckel YP
Year: 2016
Journal: BMC Cancer
Title: Placental growth factor inhibition modulates the interplay between hypoxia and unfolded protein response in hepatocellular carcinoma.
Volume: 16
Pages: 9
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9930704 | J:51759
First Author: Harding HP
Year: 1999
Journal: Nature
Title: Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase.
Volume: 397
Issue: 6716
Pages: 271-4
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25329545 | J:218404
First Author: Roobol A
Year: 2015
Journal: Biochem J
Title: p58IPK is an inhibitor of the eIF2α kinase GCN2 and its localization and expression underpin protein synthesis and ER processing capacity.
Volume: 465
Issue: 2
Pages: 213-25
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14676213 | J:217285
First Author: Kebache S
Year: 2004
Journal: J Biol Chem
Title: Nck-1 antagonizes the endoplasmic reticulum stress-induced inhibition of translation.
Volume: 279
Issue: 10
Pages: 9662-71
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Publication
29720449 | J:261540
 
First Author: Nguyen HG
Year: 2018
Journal: Sci Transl Med
Title: Development of a stress response therapy targeting aggressive prostate cancer.
Volume: 10
Issue: 439
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Publication
30894532 | J:273454
First Author: Cao Y
Year: 2019
Journal: Nat Commun
Title: ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression.
Volume: 10
Issue: 1
Pages: 1280
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Publication
17765679 | J:124971
First Author: Wu J
Year: 2007
Journal: Dev Cell
Title: ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress.
Volume: 13
Issue: 3
Pages: 351-64
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Publication
20221394 | J:158673
First Author: Ghosh R
Year: 2010
Journal: PLoS One
Title: Transcriptional regulation of VEGF-A by the unfolded protein response pathway.
Volume: 5
Issue: 3
Pages: e9575
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Publication
29717162 | J:262984
First Author: Kim KH
Year: 2018
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