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Search results 1 to 100 out of 1450 for Ptch1

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Category: Publication
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Type Details Score
Publication
18347096 | J:132980
First Author: Briggs KJ
Year: 2008
Journal: Genes Dev
Title: Cooperation between the Hic1 and Ptch1 tumor suppressors in medulloblastoma.
Volume: 22
Issue: 6
Pages: 770-85
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Publication
23223138 | J:197960
First Author: Kang HC
Year: 2013
Journal: J Invest Dermatol
Title: Ptch1 overexpression drives skin carcinogenesis and developmental defects in K14Ptch(FVB) mice.
Volume: 133
Issue: 5
Pages: 1311-20
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Publication
25833741 | J:222741
 
First Author: Cohen M
Year: 2015
Journal: Nat Commun
Title: Ptch1 and Gli regulate Shh signalling dynamics via multiple mechanisms.
Volume: 6
Pages: 6709
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Publication
19297414 | J:147994
First Author: Moraes RC
Year: 2009
Journal: Development
Title: Ptch1 is required locally for mammary gland morphogenesis and systemically for ductal elongation.
Volume: 136
Issue: 9
Pages: 1423-32
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Publication
24990743 | J:213641
First Author: Lopez-Rios J
Year: 2014
Journal: Nature
Title: Attenuated sensing of SHH by Ptch1 underlies evolution of bovine limbs.
Volume: 511
Issue: 7507
Pages: 46-51
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Publication
25448692 | J:218166
First Author: Zhulyn O
Year: 2015
Journal: Dev Biol
Title: Ptch2 shares overlapping functions with Ptch1 in Smo regulation and limb development.
Volume: 397
Issue: 2
Pages: 191-202
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Publication
20616149 | J:163642
First Author: Ishida Y
Year: 2010
Journal: Carcinogenesis
Title: Genomic and gene expression signatures of radiation in medulloblastomas after low-dose irradiation in Ptch1 heterozygous mice.
Volume: 31
Issue: 9
Pages: 1694-701
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Publication
29079783 | J:255552
First Author: Tanno B
Year: 2017
Journal: Sci Rep
Title: Nanog-driven cell-reprogramming and self-renewal maintenance in Ptch1 +/- granule cell precursors after radiation injury.
Volume: 7
Issue: 1
Pages: 14238
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Publication
27690174 | J:346574
First Author: Tsuruoka C
Year: 2016
Journal: Radiat Res
Title: Sensitive Detection of Radiation-Induced Medulloblastomas after Acute or Protracted Gamma-Ray Exposures in Ptch1 Heterozygous Mice Using a Radiation-Specific Molecular Signature.
Volume: 186
Issue: 4
Pages: 407-414
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Publication
30166346 | J:270265
First Author: Fleet AJ
Year: 2018
Journal: J Biol Chem
Title: The protein-specific activities of the transmembrane modules of Ptch1 and Ptch2 are determined by their adjacent protein domains.
Volume: 293
Issue: 43
Pages: 16583-16595
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Publication
28275010 | J:240027
First Author: Monkkonen T
Year: 2017
Journal: Development
Title: Epithelial and non-epithelial Ptch1 play opposing roles to regulate proliferation and morphogenesis of the mouse mammary gland.
Volume: 144
Issue: 7
Pages: 1317-1327
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Publication
16203740 | -
First Author: Nagao K
Year: 2005
Journal: Hum Mol Genet
Title: Detecting tissue-specific alternative splicing and disease-associated aberrant splicing of the PTCH gene with exon junction microarrays.
Volume: 14
Issue: 22
Pages: 3379-88
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Publication
15576403 | J:94269
First Author: Jeong J
Year: 2005
Journal: Development
Title: Growth and pattern of the mammalian neural tube are governed by partially overlapping feedback activities of the hedgehog antagonists patched 1 and Hhip1.
Volume: 132
Issue: 1
Pages: 143-54
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Publication
23900540 | J:199287
First Author: Holtz AM
Year: 2013
Journal: Development
Title: Essential role for ligand-dependent feedback antagonism of vertebrate hedgehog signaling by PTCH1, PTCH2 and HHIP1 during neural patterning.
Volume: 140
Issue: 16
Pages: 3423-34
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Publication
31054872 | J:278143
First Author: Ferent J
Year: 2019
Journal: Neuron
Title: Boc Acts via Numb as a Shh-Dependent Endocytic Platform for Ptch1 Internalization and Shh-Mediated Axon Guidance.
Volume: 102
Issue: 6
Pages: 1157-1171.e5
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Publication
33350496 | J:332759
     
First Author: La Sala G
Year: 2020
Journal: J Neurosci Res
Title: Gpr37l1/prosaposin receptor regulates Ptch1 trafficking, Shh production, and cell proliferation in cerebellar primary astrocytes.
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Publication
11668681 | J:72500
First Author: Izraeli S
Year: 2001
Journal: Genesis
Title: Genetic evidence that Sil is required for the Sonic Hedgehog response pathway.
Volume: 31
Issue: 2
Pages: 72-7
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Publication
31506465 | J:312496
First Author: Li C
Year: 2019
Journal: Sci Rep
Title: Patched1 haploinsufficiency severely impacts intermediary metabolism in the skin of Ptch1+/-/ODC transgenic mice.
Volume: 9
Issue: 1
Pages: 13072
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Publication
12845631 | J:84283
First Author: Kappler R
Year: 2003
Journal: J Pathol
Title: Molecular characterization of Patched-associated rhabdomyosarcoma.
Volume: 200
Issue: 3
Pages: 348-56
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Publication
21266456 | J:170123
First Author: Trazzi S
Year: 2011
Journal: Hum Mol Genet
Title: APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome.
Volume: 20
Issue: 8
Pages: 1560-73
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Publication
17230190 | J:118622
First Author: Wakabayashi Y
Year: 2007
Journal: Nature
Title: Promotion of Hras-induced squamous carcinomas by a polymorphic variant of the Patched gene in FVB mice.
Volume: 445
Issue: 7129
Pages: 761-5
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Publication
10498679 | J:56195
First Author: Milenkovic L
Year: 1999
Journal: Development
Title: Mouse patched1 controls body size determination and limb patterning.
Volume: 126
Issue: 20
Pages: 4431-40
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Publication
31482846 | J:281729
   
First Author: Deng Q
Year: 2019
Journal: Elife
Title: Activation of hedgehog signaling in mesenchymal stem cells induces cartilage and bone tumor formation via Wnt/β-Catenin.
Volume: 8
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37527037 | J:339299
First Author: Wang Q
Year: 2023
Journal: Cell Rep
Title: Hedgehog receptors exert immune-surveillance roles in the epidermis across species.
Volume: 42
Issue: 8
Pages: 112929
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18477452 | J:135169
First Author: Ohba S
Year: 2008
Journal: Dev Cell
Title: Patched1 haploinsufficiency increases adult bone mass and modulates Gli3 repressor activity.
Volume: 14
Issue: 5
Pages: 689-99
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Publication
32112900 | J:286791
 
First Author: Niesen J
Year: 2020
Journal: Cancer Lett
Title: Pik3ca mutations significantly enhance the growth of SHH medulloblastoma and lead to metastatic tumour growth in a novel mouse model.
Volume: 477
Pages: 10-18
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Publication
23897749 | J:204468
First Author: Feng W
Year: 2013
Journal: Genesis
Title: The Ptch1(DL) mouse: a new model to study lambdoid craniosynostosis and basal cell nevus syndrome-associated skeletal defects.
Volume: 51
Issue: 10
Pages: 677-89
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Publication
15172986 | J:90301
First Author: Pazzaglia S
Year: 2004
Journal: Cancer Res
Title: Modulation of patched-associated susceptibility to radiation induced tumorigenesis by genetic background.
Volume: 64
Issue: 11
Pages: 3798-806
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Publication
14871823 | J:88072
First Author: Mancuso M
Year: 2004
Journal: Cancer Res
Title: Basal cell carcinoma and its development: insights from radiation-induced tumors in Ptch1-deficient mice.
Volume: 64
Issue: 3
Pages: 934-41
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Publication
27626168 | J:268866
First Author: Tanno B
Year: 2016
Journal: Oncotarget
Title: Ex vivo miRNome analysis in Ptch1+/- cerebellum granule cells reveals a subset of miRNAs involved in radiation-induced medulloblastoma.
Volume: 7
Issue: 42
Pages: 68253-68269
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Publication
30833624 | J:276693
First Author: Tam A
Year: 2019
Journal: Sci Rep
Title: Hedgehog signaling in the airway epithelium of patients with chronic obstructive pulmonary disease.
Volume: 9
Issue: 1
Pages: 3353
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Publication
17287253 | J:118936
First Author: Moraes RC
Year: 2007
Journal: Development
Title: Constitutive activation of smoothened (SMO) in mammary glands of transgenic mice leads to increased proliferation, altered differentiation and ductal dysplasia.
Volume: 134
Issue: 6
Pages: 1231-42
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Publication
16273213 | J:104180
First Author: Uhmann A
Year: 2005
Journal: Int J Oncol
Title: A model for PTCH1/Ptch1-associated tumors comprising mutational inactivation and gene silencing.
Volume: 27
Issue: 6
Pages: 1567-75
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Publication
32113901 | J:317024
 
First Author: Jackson TW
Year: 2020
Journal: Neurotoxicol Teratol
Title: Heterozygous mutation of sonic hedgehog receptor (Ptch1) drives cerebellar overgrowth and sex-specifically alters hippocampal and cortical layer structure, activity, and social behavior in female mice.
Volume: 78
Pages: 106866
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Publication
35196485 | J:337684
First Author: Xie Y
Year: 2022
Journal: Cell Rep
Title: Astrocyte-neuron crosstalk through Hedgehog signaling mediates cortical synapse development.
Volume: 38
Issue: 8
Pages: 110416
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25263791 | J:315075
First Author: Mille F
Year: 2014
Journal: Dev Cell
Title: The Shh receptor Boc promotes progression of early medulloblastoma to advanced tumors.
Volume: 31
Issue: 1
Pages: 34-47
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26997276 | J:234877
First Author: Tamayo-Orrego L
Year: 2016
Journal: Cell Rep
Title: Evasion of Cell Senescence Leads to Medulloblastoma Progression.
Volume: 14
Issue: 12
Pages: 2925-37
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29983323 | J:269512
First Author: Furey CG
Year: 2018
Journal: Neuron
Title: De Novo Mutation in Genes Regulating Neural Stem Cell Fate in Human Congenital Hydrocephalus.
Volume: 99
Issue: 2
Pages: 302-314.e4
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19164512 | J:144617
First Author: Frappart PO
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Recurrent genomic alterations characterize medulloblastoma arising from DNA double-strand break repair deficiency.
Volume: 106
Issue: 6
Pages: 1880-5
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Publication
25292199 | J:218093
First Author: Aoto K
Year: 2015
Journal: Hum Mol Genet
Title: Co-ordinated brain and craniofacial development depend upon Patched1/XIAP regulation of cell survival.
Volume: 24
Issue: 3
Pages: 698-713
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Publication
19877269 | J:154373
First Author: Town L
Year: 2009
Journal: Dev Dyn
Title: The metalloendopeptidase gene Pitrm1 is regulated by hedgehog signaling in the developing mouse limb and is expressed in muscle progenitors.
Volume: 238
Issue: 12
Pages: 3175-84
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25842978 | J:224706
First Author: Peterson SC
Year: 2015
Journal: Cell Stem Cell
Title: Basal cell carcinoma preferentially arises from stem cells within hair follicle and mechanosensory niches.
Volume: 16
Issue: 4
Pages: 400-12
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16849540 | J:112118
First Author: Lee Y
Year: 2006
Journal: Cancer Res
Title: Patched2 modulates tumorigenesis in patched1 heterozygous mice.
Volume: 66
Issue: 14
Pages: 6964-71
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25834022 | J:221426
First Author: Liu J
Year: 2015
Journal: Development
Title: The loss of Hh responsiveness by a non-ciliary Gli2 variant.
Volume: 142
Issue: 9
Pages: 1651-60
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Publication
24990742 | J:213642
First Author: Cooper KL
Year: 2014
Journal: Nature
Title: Patterning and post-patterning modes of evolutionary digit loss in mammals.
Volume: 511
Issue: 7507
Pages: 41-5
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Publication
21447392 | J:177960
First Author: Gavino C
Year: 2011
Journal: Mol Cell Neurosci
Title: Patched1 haploinsufficiency impairs ependymal cilia function of the quaking viable mice, leading to fatal hydrocephalus.
Volume: 47
Issue: 2
Pages: 100-7
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Publication
32820036 | J:303706
First Author: Kutscher LM
Year: 2020
Journal: Genes Dev
Title: Functional loss of a noncanonical BCOR-PRC1.1 complex accelerates SHH-driven medulloblastoma formation.
Volume: 34
Issue: 17-18
Pages: 1161-1176
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Publication
22968113 | J:188115
First Author: Chang H
Year: 2012
Journal: Dev Biol
Title: Mammary epithelial-restricted expression of activated c-src rescues the block to mammary gland morphogenesis due to the deletion of the C-terminus of Patched-1.
Volume: 370
Issue: 2
Pages: 187-97
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Publication
28630165 | J:250545
First Author: Katic J
Year: 2017
Journal: J Cell Sci
Title: The cell adhesion molecule CHL1 interacts with patched-1 to regulate apoptosis during postnatal cerebellar development.
Volume: 130
Issue: 15
Pages: 2606-2619
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19483124 | J:151338
First Author: Siggins SL
Year: 2009
Journal: Blood
Title: The Hedgehog receptor Patched1 regulates myeloid and lymphoid progenitors by distinct cell-extrinsic mechanisms.
Volume: 114
Issue: 5
Pages: 995-1004
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Publication
23404854 | J:231264
First Author: Villani RM
Year: 2013
Journal: Endocr Relat Cancer
Title: Murine basal cell carcinoma leads to tumor-mediated alterations in endocrine Igf1 signaling.
Volume: 20
Issue: 3
Pages: 273-81
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Publication
30452905 | J:272049
 
First Author: Di Pietro C
Year: 2019
Journal: Exp Neurol
Title: Genetic ablation of Gpr37l1 delays tumor occurrence in Ptch1+/- mouse models of medulloblastoma.
Volume: 312
Pages: 33-42
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19234491 | J:147583
First Author: Thomas WD
Year: 2009
Journal: Oncogene
Title: Patched1 deletion increases N-Myc protein stability as a mechanism of medulloblastoma initiation and progression.
Volume: 28
Issue: 13
Pages: 1605-15
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19995795 | J:160726
First Author: Davari P
Year: 2010
Journal: Carcinogenesis
Title: Loss of Blm enhances basal cell carcinoma and rhabdomyosarcoma tumorigenesis in Ptch1+/- mice.
Volume: 31
Issue: 6
Pages: 968-73
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19252479 | J:147878
First Author: Gao B
Year: 2009
Journal: Nature
Title: A mutation in Ihh that causes digit abnormalities alters its signalling capacity and range.
Volume: 458
Issue: 7242
Pages: 1196-200
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32332736 | J:291852
First Author: Kim Y
Year: 2020
Journal: Nat Commun
Title: Ptch2/Gas1 and Ptch1/Boc differentially regulate Hedgehog signalling in murine primordial germ cell migration.
Volume: 11
Issue: 1
Pages: 1994
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35472633 | J:324690
 
First Author: Wang H
Year: 2022
Journal: Matrix Biol
Title: Hedgehog signaling orchestrates cartilage-to-bone transition independently of Smoothened.
Volume: 110
Pages: 76-90
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34752747 | J:314131
First Author: Fujii K
Year: 2021
Journal: Dev Cell
Title: Controlling tissue patterning by translational regulation of signaling transcripts through the core translation factor eIF3c.
Volume: 56
Issue: 21
Pages: 2928-2937.e9
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25995356 | J:239367
First Author: Stasiulewicz M
Year: 2015
Journal: Development
Title: A conserved role for Notch signaling in priming the cellular response to Shh through ciliary localisation of the key Shh transducer Smo.
Volume: 142
Issue: 13
Pages: 2291-303
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25458012 | J:315774
First Author: Junker JP
Year: 2014
Journal: Dev Cell
Title: A predictive model of bifunctional transcription factor signaling during embryonic tissue patterning.
Volume: 31
Issue: 4
Pages: 448-60
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15480423 | J:94710
First Author: Kappler R
Year: 2004
Journal: Oncogene
Title: Profiling the molecular difference between Patched- and p53-dependent rhabdomyosarcoma.
Volume: 23
Issue: 54
Pages: 8785-95
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30487124 | J:320766
First Author: Rodriguez-Blanco J
Year: 2019
Journal: Clin Cancer Res
Title: A CK1α Activator Penetrates the Brain and Shows Efficacy Against Drug-resistant Metastatic Medulloblastoma.
Volume: 25
Issue: 4
Pages: 1379-1388
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35931079 | J:328995
First Author: Zhang SF
Year: 2022
Journal: Stem Cell Reports
Title: The epigenetic state of EED-Gli3-Gli1 regulatory axis controls embryonic cortical neurogenesis.
Volume: 17
Issue: 9
Pages: 2064-2080
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24492243 | J:210838
First Author: Adolphe C
Year: 2014
Journal: J Invest Dermatol
Title: Patched 1 and patched 2 redundancy has a key role in regulating epidermal differentiation.
Volume: 134
Issue: 7
Pages: 1981-1990
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25901736 | J:233472
First Author: Vaillant C
Year: 2015
Journal: PLoS One
Title: Serpine2/PN-1 Is Required for Proliferative Expansion of Pre-Neoplastic Lesions and Malignant Progression to Medulloblastoma.
Volume: 10
Issue: 4
Pages: e0124870
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17611698 | J:132006
First Author: Eichenmüller M
Year: 2007
Journal: Int J Oncol
Title: Hedgehog-independent overexpression of transforming growth factor-beta1 in rhabdomyosarcoma of Patched1 mutant mice.
Volume: 31
Issue: 2
Pages: 405-12
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25885794 | J:224638
First Author: Cookman CJ
Year: 2015
Journal: Endocrinology
Title: Estrogen Receptor-β Up-Regulates IGF1R Expression and Activity to Inhibit Apoptosis and Increase Growth of Medulloblastoma.
Volume: 156
Issue: 7
Pages: 2395-408
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31145830 | J:294075
First Author: Binder M
Year: 2019
Journal: Stem Cells
Title: Functionally Distinctive Ptch Receptors Establish Multimodal Hedgehog Signaling in the Tooth Epithelial Stem Cell Niche.
Volume: 37
Issue: 9
Pages: 1238-1248
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15269168 | J:92058
First Author: Tian H
Year: 2004
Journal: Development
Title: Dose dependency of Disp1 and genetic interaction between Disp1 and other hedgehog signaling components in the mouse.
Volume: 131
Issue: 16
Pages: 4021-33
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25164012 | J:216695
First Author: Palmer CJ
Year: 2014
Journal: Cancer Res
Title: Zfx facilitates tumorigenesis caused by activation of the Hedgehog pathway.
Volume: 74
Issue: 20
Pages: 5914-24
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19394325 | J:150375
First Author: Cobourne MT
Year: 2009
Journal: Dev Biol
Title: Sonic hedgehog signalling inhibits palatogenesis and arrests tooth development in a mouse model of the nevoid basal cell carcinoma syndrome.
Volume: 331
Issue: 1
Pages: 38-49
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19196975 | J:146492
First Author: Uziel T
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: The miR-17~92 cluster collaborates with the Sonic Hedgehog pathway in medulloblastoma.
Volume: 106
Issue: 8
Pages: 2812-7
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34423857 | J:315670
First Author: Hruba E
Year: 2021
Journal: J Bone Miner Res
Title: Loss of Sprouty Produces a Ciliopathic Skeletal Phenotype in Mice Through Upregulation of Hedgehog Signaling.
Volume: 36
Issue: 11
Pages: 2258-2274
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19020777 | J:143554
First Author: Wendling DS
Year: 2008
Journal: Int J Mol Med
Title: Characteristic overexpression of the forkhead box transcription factor Foxf1 in Patched-associated tumors.
Volume: 22
Issue: 6
Pages: 787-92
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28799057 | J:257526
First Author: Feuerstein M
Year: 2017
Journal: Cell Tissue Res
Title: Expression patterns of key Sonic Hedgehog signaling pathway components in the developing and adult mouse midbrain and in the MN9D cell line.
Volume: 370
Issue: 2
Pages: 211-225
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24757136 | J:317276
First Author: Dittmann K
Year: 2014
Journal: Arthritis Rheumatol
Title: Inactivation of patched1 in murine chondrocytes causes spinal fusion without inflammation.
Volume: 66
Issue: 4
Pages: 831-40
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Publication
22064698 | J:316104
First Author: Song L
Year: 2012
Journal: Cell Res
Title: Shh signaling guides spatial pathfinding of raphespinal tract axons by multidirectional repulsion.
Volume: 22
Issue: 4
Pages: 697-716
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27498049 | J:238285
First Author: Adolphe C
Year: 2017
Journal: J Invest Dermatol
Title: Patched Receptors Sense, Interpret, and Establish an Epidermal Hedgehog Signaling Gradient.
Volume: 137
Issue: 1
Pages: 179-186
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Publication
28939119 | J:245959
 
First Author: Ho UY
Year: 2017
Journal: Mech Dev
Title: Patched1 patterns Fibroblast growth factor 10 and Forkhead box F1 expression during pulmonary branch formation.
Volume: 147
Pages: 37-48
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Publication
21821669 | J:175841
First Author: Lana-Elola E
Year: 2011
Journal: Hum Mol Genet
Title: Noggin null allele mice exhibit a microform of holoprosencephaly.
Volume: 20
Issue: 20
Pages: 4005-15
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21841314 | J:178246
First Author: Ngan ES
Year: 2011
Journal: J Clin Invest
Title: Hedgehog/Notch-induced premature gliogenesis represents a new disease mechanism for Hirschsprung disease in mice and humans.
Volume: 121
Issue: 9
Pages: 3467-78
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Publication
21292980 | J:172775
First Author: Gildea DE
Year: 2011
Journal: FASEB J
Title: The pleiotropic mouse phenotype extra-toes spotting is caused by translation initiation factor Eif3c mutations and is associated with disrupted sonic hedgehog signaling.
Volume: 25
Issue: 5
Pages: 1596-605
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24803588 | J:213513
First Author: Gao Y
Year: 2014
Journal: Development
Title: WT1 regulates the development of the posterior taste field.
Volume: 141
Issue: 11
Pages: 2271-8
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Publication
16489008 | J:106653
First Author: Adolphe C
Year: 2006
Journal: Cancer Res
Title: Patched1 functions as a gatekeeper by promoting cell cycle progression.
Volume: 66
Issue: 4
Pages: 2081-8
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Publication
34767969 | J:316184
 
First Author: Hussein MT
Year: 2021
Journal: Gene Expr Patterns
Title: Spatiotemporal expression of sonic hedgehog signalling molecules in the embryonic mesencephalic dopaminergic neurons.
Volume: 42
Pages: 119217
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Journal: Development
Title: Evc is a positive mediator of Ihh-regulated bone growth that localises at the base of chondrocyte cilia.
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Title: Cranial nerve development requires co-ordinated Shh and canonical Wnt signaling.
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Title: Hedgehog regulates distinct vascular patterning events through VEGF-dependent and -independent mechanisms.
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Title: Analysis of Nsdhl-deficient embryos reveals a role for Hedgehog signaling in early placental development.
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Title: Progenitor cell expansion and organ size of mouse adrenal is regulated by sonic hedgehog.
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Title: Teashirt 3 is necessary for ureteral smooth muscle differentiation downstream of SHH and BMP4.
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Title: Control of glial precursor cell development in the mouse optic nerve by sonic hedgehog from retinal ganglion cells.
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Title: Patched1 is required in neural crest cells for the prevention of orofacial clefts.
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Title: Ptch1-mediated dosage-dependent action of Shh signaling regulates neural progenitor development at late gestational stages.
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Title: NFAT5/TonEBP controls early acquisition of notochord phenotypic markers, collagen composition, and sonic hedgehog signaling during mouse intervertebral disc embryogenesis.
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Title: Mutations in Hedgehog acyltransferase (Hhat) perturb Hedgehog signaling, resulting in severe acrania-holoprosencephaly-agnathia craniofacial defects.
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