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Search results 1 to 100 out of 227 for Map2k1

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Category: Publication
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Type Details Score
Publication
16887817 | J:112223
First Author: Bissonauth V
Year: 2006
Journal: Development
Title: Requirement for Map2k1 (Mek1) in extra-embryonic ectoderm during placentogenesis.
Volume: 133
Issue: 17
Pages: 3429-40
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Publication
19304888 | J:147279
First Author: Nadeau V
Year: 2009
Journal: Development
Title: Map2k1 and Map2k2 genes contribute to the normal development of syncytiotrophoblasts during placentation.
Volume: 136
Issue: 8
Pages: 1363-74
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Publication
22491947 | J:184010
First Author: Ishii K
Year: 2012
Journal: Development
Title: FGF2 mediates mouse spermatogonial stem cell self-renewal via upregulation of Etv5 and Bcl6b through MAP2K1 activation.
Volume: 139
Issue: 10
Pages: 1734-43
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Publication
11101507 | J:66102
First Author: Bueno OF
Year: 2000
Journal: EMBO J
Title: The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice.
Volume: 19
Issue: 23
Pages: 6341-50
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Publication
22904158 | J:191817
First Author: Maejima Y
Year: 2012
Journal: Am J Physiol Heart Circ Physiol
Title: Constitutively active MEK1 rescues cardiac dysfunction caused by overexpressed GSK-3α during aging and hemodynamic pressure overload.
Volume: 303
Issue: 8
Pages: H979-88
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Publication
19219045 | J:199705
First Author: Catalanotti F
Year: 2009
Journal: Nat Struct Mol Biol
Title: A Mek1-Mek2 heterodimer determines the strength and duration of the Erk signal.
Volume: 16
Issue: 3
Pages: 294-303
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Publication
35975983 | J:344110
   
First Author: Kim JM
Year: 2022
Journal: Elife
Title: Biphasic regulation of osteoblast development via the ERK MAPK-mTOR pathway.
Volume: 11
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Publication
24948605 | J:213868
First Author: Nadeau V
Year: 2014
Journal: Development
Title: Essential role of the ERK/MAPK pathway in blood-placental barrier formation.
Volume: 141
Issue: 14
Pages: 2825-37
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Publication
26814233 | J:258488
First Author: Aoidi R
Year: 2016
Journal: Sci Signal
Title: Functional redundancy of the kinases MEK1 and MEK2: Rescue of the Mek1 mutant phenotype by Mek2 knock-in reveals a protein threshold effect.
Volume: 9
Issue: 412
Pages: ra9
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Publication
19017799 | J:142212
First Author: Krenz M
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Role of ERK1/2 signaling in congenital valve malformations in Noonan syndrome.
Volume: 105
Issue: 48
Pages: 18930-5
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Publication
33570093 | J:306389
First Author: Holter MC
Year: 2021
Journal: Cereb Cortex
Title: Hyperactive MEK1 Signaling in Cortical GABAergic Neurons Promotes Embryonic Parvalbumin Neuron Loss and Defects in Behavioral Inhibition.
Volume: 31
Issue: 6
Pages: 3064-3081
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Publication
29590634 | J:261678
 
First Author: Aoidi R
Year: 2018
Journal: Dis Model Mech
Title: Mek1Y130C mice recapitulate aspects of human cardio-facio-cutaneous syndrome.
Volume: 11
Issue: 3
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Publication
26848828 | J:230714
   
First Author: Xing L
Year: 2016
Journal: Elife
Title: Layer specific and general requirements for ERK/MAPK signaling in the developing neocortex.
Volume: 5
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Publication
22998872 | J:188328
First Author: Li X
Year: 2012
Journal: Neuron
Title: MEK Is a Key Regulator of Gliogenesis in the Developing Brain.
Volume: 75
Issue: 6
Pages: 1035-50
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Publication
1411546 | J:25190
First Author: Crews CM
Year: 1992
Journal: Science
Title: The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product.
Volume: 258
Issue: 5081
Pages: 478-80
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Publication
29804890 | J:271534
First Author: Baumgartner C
Year: 2018
Journal: Cell Stem Cell
Title: An ERK-Dependent Feedback Mechanism Prevents Hematopoietic Stem Cell Exhaustion.
Volume: 22
Issue: 6
Pages: 879-892.e6
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Publication
33470189 | J:305676
First Author: Shneider BL
Year: 2021
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Constitutive activation of mitogen-activated protein kinase kinase (MEK1) in ileal enterocytes leads to dysplasia and a predisposition to cancer.
Volume: 320
Issue: 3
Pages: G366-G379
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Publication
28851708 | J:245732
First Author: Bluhm B
Year: 2017
Journal: Development
Title: miR-322 stabilizes MEK1 expression to inhibit RAF/MEK/ERK pathway activation in cartilage.
Volume: 144
Issue: 19
Pages: 3562-3577
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Publication
15304090 | J:92906
First Author: Hobbs RM
Year: 2004
Journal: J Invest Dermatol
Title: Expression of activated MEK1 in differentiating epidermal cells is sufficient to generate hyperproliferative and inflammatory skin lesions.
Volume: 123
Issue: 3
Pages: 503-15
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Publication
11222509 | J:67800
First Author: Gong X
Year: 2001
Journal: Invest Ophthalmol Vis Sci
Title: Development of cataractous macrophthalmia in mice expressing an active MEK1 in the lens.
Volume: 42
Issue: 3
Pages: 539-48
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Publication
10838075 | J:62682
First Author: Sommer A
Year: 2000
Journal: FEBS Lett
Title: Synergistic activation of the mkp-1 gene by protein kinase A signaling and USF, but not c-Myc.
Volume: 474
Issue: 2-3
Pages: 146-50
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Publication
8168826 | J:18069
First Author: Emslie EA
Year: 1994
Journal: Hum Genet
Title: The CL100 gene, which encodes a dual specificity (Tyr/Thr) MAP kinase phosphatase, is highly conserved and maps to human chromosome 5q34.
Volume: 93
Issue: 5
Pages: 513-6
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Publication
8602223 | J:31469
First Author: Druey KM
Year: 1996
Journal: Nature
Title: Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family.
Volume: 379
Issue: 6567
Pages: 742-6
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8632902 | J:31640
First Author: Cano E
Year: 1996
Journal: Oncogene
Title: Identification of anisomycin-activated kinases p45 and p55 in murine cells as MAPKAP kinase-2.
Volume: 12
Issue: 4
Pages: 805-12
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Publication
9208850 | J:41174
First Author: Kornhauser JM
Year: 1997
Journal: Neuron
Title: A kinase to remember: dual roles for MAP kinase in long-term memory.
Volume: 18
Issue: 6
Pages: 839-42
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Publication
16463380 | J:134126
First Author: Bloom MW
Year: 2006
Journal: Anat Rec A Discov Mol Cell Evol Biol
Title: Aspects of achondroplasia in the skulls of dwarf transgenic mice: a cephalometric study.
Volume: 288
Issue: 3
Pages: 316-22
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Publication
19023081 | J:142351
First Author: Imai J
Year: 2008
Journal: Science
Title: Regulation of pancreatic beta cell mass by neuronal signals from the liver.
Volume: 322
Issue: 5905
Pages: 1250-4
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Publication
23727409 | J:202538
First Author: Wang S
Year: 2013
Journal: Biochim Biophys Acta
Title: ERK-mediated suppression of cilia in cisplatin-induced tubular cell apoptosis and acute kidney injury.
Volume: 1832
Issue: 10
Pages: 1582-90
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Publication
23735655 | J:199704
First Author: Kocieniewski P
Year: 2013
Journal: Phys Biol
Title: MEK1 and MEK2 differentially control the duration and amplitude of the ERK cascade response.
Volume: 10
Issue: 3
Pages: 035006
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Publication
23480967 | J:201229
First Author: Matzkin ME
Year: 2013
Journal: Mol Cell Endocrinol
Title: The ERK1/2 pathway regulates testosterone synthesis by coordinately regulating the expression of steroidogenic genes in Leydig cells.
Volume: 370
Issue: 1-2
Pages: 130-7
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Publication
36189831 | J:330244
 
First Author: Kwon HN
Year: 2022
Journal: Development
Title: Omics profiling identifies the regulatory functions of the MAPK/ERK pathway in nephron progenitor metabolism.
Volume: 149
Issue: 19
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Publication
19198628 | J:147586
First Author: Scholl FA
Year: 2009
Journal: Oncogene
Title: Mek1/2 gene dosage determines tissue response to oncogenic Ras signaling in the skin.
Volume: 28
Issue: 12
Pages: 1485-95
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Publication
17419998 | J:122484
First Author: Scholl FA
Year: 2007
Journal: Dev Cell
Title: Mek1/2 MAPK kinases are essential for Mammalian development, homeostasis, and Raf-induced hyperplasia.
Volume: 12
Issue: 4
Pages: 615-29
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Publication
31801908 | J:285258
 
First Author: Long ME
Year: 2019
Journal: JCI Insight
Title: MEK1 regulates pulmonary macrophage inflammatory responses and resolution of acute lung injury.
Volume: 4
Issue: 23
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21527500 | J:278979
First Author: Yamashita S
Year: 2011
Journal: Mol Endocrinol
Title: The Leydig cell MEK/ERK pathway is critical for maintaining a functional population of adult Leydig cells and for fertility.
Volume: 25
Issue: 7
Pages: 1211-22
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Publication
19383924 | J:148265
First Author: Scholl FA
Year: 2009
Journal: Cancer Res
Title: Selective role for Mek1 but not Mek2 in the induction of epidermal neoplasia.
Volume: 69
Issue: 9
Pages: 3772-8
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Publication
25491074 | J:219604
First Author: Noël A
Year: 2015
Journal: Neurobiol Aging
Title: ERK (MAPK) does not phosphorylate tau under physiological conditions in vivo or in vitro.
Volume: 36
Issue: 2
Pages: 901-2
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Publication
12832465 | J:84382
First Author: Bélanger LF
Year: 2003
Journal: Mol Cell Biol
Title: Mek2 is dispensable for mouse growth and development.
Volume: 23
Issue: 14
Pages: 4778-87
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Publication
21699731 | J:327220
 
First Author: Fritz JM
Year: 2011
Journal: Mol Cancer
Title: Stimulation of neoplastic mouse lung cell proliferation by alveolar macrophage-derived, insulin-like growth factor-1 can be blocked by inhibiting MEK and PI3K activation.
Volume: 10
Pages: 76
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Publication
20179103 | J:175345
First Author: Pan CQ
Year: 2010
Journal: J Cell Sci
Title: Active Mek2 as a regulatory scaffold that promotes Pin1 binding to BPGAP1 to suppress BPGAP1-induced acute Erk activation and cell migration.
Volume: 123
Issue: Pt 6
Pages: 903-16
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19144315 | J:143721
First Author: Conche C
Year: 2009
Journal: Immunity
Title: T cell adhesion primes antigen receptor-induced calcium responses through a transient rise in adenosine 3',5'-cyclic monophosphate.
Volume: 30
Issue: 1
Pages: 33-43
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Publication
28746311 | J:252615
First Author: Choi J
Year: 2017
Journal: Nature
Title: Prolonged Mek1/2 suppression impairs the developmental potential of embryonic stem cells.
Volume: 548
Issue: 7666
Pages: 219-223
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24746703 | J:210622
First Author: Chen T
Year: 2014
Journal: Cancer Cell
Title: Small GTPase RBJ mediates nuclear entrapment of MEK1/MEK2 in tumor progression.
Volume: 25
Issue: 5
Pages: 682-96
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Publication
7914033 | J:46351
First Author: Han J
Year: 1994
Journal: Science
Title: A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells.
Volume: 265
Issue: 5173
Pages: 808-11
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Publication
24045785 | J:317231
 
First Author: Whittington RA
Year: 2013
Journal: Sci Rep
Title: Anesthesia-induced hypothermia mediates decreased ARC gene and protein expression through ERK/MAPK inactivation.
Volume: 3
Pages: 1388
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28003382 | J:253107
First Author: Long ME
Year: 2017
Journal: J Immunol
Title: MEK1/2 Inhibition Promotes Macrophage Reparative Properties.
Volume: 198
Issue: 2
Pages: 862-872
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26208884 | J:278579
First Author: Bouhamdan M
Year: 2015
Journal: Cell Signal
Title: MEK1 dependent and independent ERK activation regulates IL-10 and IL-12 production in bone marrow derived macrophages.
Volume: 27
Issue: 10
Pages: 2068-76
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Publication
23453810 | J:198142
First Author: Zmajkovicova K
Year: 2013
Journal: Mol Cell
Title: MEK1 is required for PTEN membrane recruitment, AKT regulation, and the maintenance of peripheral tolerance.
Volume: 50
Issue: 1
Pages: 43-55
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Publication
21041641 | J:166606
First Author: Arwert EN
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Tumor formation initiated by nondividing epidermal cells via an inflammatory infiltrate.
Volume: 107
Issue: 46
Pages: 19903-8
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27913296 | J:303014
First Author: Dungan CM
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Regulation of skeletal muscle insulin-stimulated signaling through the MEK-REDD1-mTOR axis.
Volume: 482
Issue: 4
Pages: 1067-1072
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Publication
23283332 | J:193409
First Author: Ishii A
Year: 2013
Journal: J Neurosci
Title: Sustained activation of ERK1/2 MAPK in oligodendrocytes and schwann cells enhances myelin growth and stimulates oligodendrocyte progenitor expansion.
Volume: 33
Issue: 1
Pages: 175-86
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Publication
25218145 | J:220091
First Author: Muchir A
Year: 2014
Journal: Biochem Biophys Res Commun
Title: Mitogen-activated protein kinase kinase 1/2 inhibition and angiotensin II converting inhibition in mice with cardiomyopathy caused by lamin A/C gene mutation.
Volume: 452
Issue: 4
Pages: 958-61
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Publication
16761309 | J:115834
First Author: Labuda T
Year: 2006
Journal: Eur J Immunol
Title: MEK kinase 1 is a negative regulator of virus-specific CD8(+) T cells.
Volume: 36
Issue: 8
Pages: 2076-84
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Publication
18202127 | J:326637
First Author: Beith JL
Year: 2008
Journal: Endocrinology
Title: Insulin stimulates primary beta-cell proliferation via Raf-1 kinase.
Volume: 149
Issue: 5
Pages: 2251-60
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15546878 | J:96860
First Author: Burack WR
Year: 2005
Journal: J Biol Chem
Title: Live Cell Imaging of ERK and MEK: simple binding equilibrium explains the regulated nucleocytoplasmic distribution of ERK.
Volume: 280
Issue: 5
Pages: 3832-7
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Publication
9806642 | J:110525
First Author: Sugawara T
Year: 1998
Journal: Immunity
Title: Differential roles of ERK and p38 MAP kinase pathways in positive and negative selection of T lymphocytes.
Volume: 9
Issue: 4
Pages: 565-74
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22056560 | J:178631
First Author: Choi YH
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Osterix is regulated by Erk1/2 during osteoblast differentiation.
Volume: 415
Issue: 3
Pages: 472-8
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23637887 | J:200561
First Author: Chiang PY
Year: 2013
Journal: PLoS One
Title: Phosphorylation of mRNA decapping protein Dcp1a by the ERK signaling pathway during early differentiation of 3T3-L1 preadipocytes.
Volume: 8
Issue: 4
Pages: e61697
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27741509 | J:319205
First Author: Nowacka JD
Year: 2016
Journal: Oncotarget
Title: MEK1 is required for the development of NRAS-driven leukemia.
Volume: 7
Issue: 49
Pages: 80113-80130
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19565474 | J:180564
First Author: Yao Z
Year: 2009
Journal: Biofactors
Title: The ERK signaling cascade--views from different subcellular compartments.
Volume: 35
Issue: 5
Pages: 407-16
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8385802 | J:29891
First Author: Lange-Carter CA
Year: 1993
Journal: Science
Title: A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf.
Volume: 260
Issue: 5106
Pages: 315-9
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12875843 | J:84659
First Author: Gotter AL
Year: 2003
Journal: J Mol Biol
Title: Tipin, a novel timeless-interacting protein, is developmentally co-expressed with timeless and disrupts its self-association.
Volume: 331
Issue: 1
Pages: 167-76
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8602221 | J:31470
First Author: Hamilton BA
Year: 1996
Journal: Nature
Title: Disruption of the nuclear hormone receptor RORalpha in staggerer mice.
Volume: 379
Issue: 6567
Pages: 736-9
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16908534 | J:114676
First Author: Hamazaki T
Year: 2006
Journal: Mol Cell Biol
Title: The Grb2/Mek pathway represses Nanog in murine embryonic stem cells.
Volume: 26
Issue: 20
Pages: 7539-49
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Publication
10209122 | J:54197
First Author: Giroux S
Year: 1999
Journal: Curr Biol
Title: Embryonic death of Mek1-deficient mice reveals a role for this kinase in angiogenesis in the labyrinthine region of the placenta.
Volume: 9
Issue: 7
Pages: 369-72
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Publication
24463270 | J:331285
First Author: Boggiatto PM
Year: 2014
Journal: Microbes Infect
Title: Targeted extracellular signal-regulated kinase activation mediated by Leishmania amazonensis requires MP1 scaffold.
Volume: 16
Issue: 4
Pages: 328-36
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Publication
34386488 | J:311510
 
First Author: Beuret L
Year: 2021
Journal: Front Cell Dev Biol
Title: Mek1 and Mek2 Functional Redundancy in Erythropoiesis.
Volume: 9
Pages: 639022
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Publication
35021072 | J:320530
First Author: Houde N
Year: 2022
Journal: Cell Rep
Title: Fine-tuning of MEK signaling is pivotal for limiting B and T cell activation.
Volume: 38
Issue: 2
Pages: 110223
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Publication
35122074 | J:322704
First Author: Falcomatà C
Year: 2022
Journal: Nat Cancer
Title: Selective multi-kinase inhibition sensitizes mesenchymal pancreatic cancer to immune checkpoint blockade by remodeling the tumor microenvironment.
Volume: 3
Issue: 3
Pages: 318-336
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14871928 | J:88286
First Author: Murakami S
Year: 2004
Journal: Genes Dev
Title: Constitutive activation of MEK1 in chondrocytes causes Stat1-independent achondroplasia-like dwarfism and rescues the Fgfr3-deficient mouse phenotype.
Volume: 18
Issue: 3
Pages: 290-305
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26660732 | J:246443
First Author: Bowles KR
Year: 2015
Journal: PLoS One
Title: Huntingtin Subcellular Localisation Is Regulated by Kinase Signalling Activity in the StHdhQ111 Model of HD.
Volume: 10
Issue: 12
Pages: e0144864
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14563325 | J:86182
First Author: Han A
Year: 2003
Journal: Immunity
Title: Bam32 links the B cell receptor to ERK and JNK and mediates B cell proliferation but not survival.
Volume: 19
Issue: 4
Pages: 621-32
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8388392 | J:31929
First Author: Zheng CF
Year: 1993
Journal: J Biol Chem
Title: Cloning and characterization of two distinct human extracellular signal-regulated kinase activator kinases, MEK1 and MEK2.
Volume: 268
Issue: 15
Pages: 11435-9
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16199873 | J:101350
First Author: Abell AN
Year: 2005
Journal: Mol Cell Biol
Title: Ablation of MEKK4 kinase activity causes neurulation and skeletal patterning defects in the mouse embryo.
Volume: 25
Issue: 20
Pages: 8948-59
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22393900 | J:184475
First Author: Wang X
Year: 2012
Journal: J Neurochem
Title: Activation of the extracellular signal-regulated kinase pathway contributes to the behavioral deficit of fragile x-syndrome.
Volume: 121
Issue: 4
Pages: 672-9
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16148006 | J:200303
First Author: Tárrega C
Year: 2005
Journal: J Biol Chem
Title: ERK2 shows a restrictive and locally selective mechanism of recognition by its tyrosine phosphatase inactivators not shared by its activator MEK1.
Volume: 280
Issue: 45
Pages: 37885-94
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9149902 | J:40857
First Author: Alessandrini A
Year: 1997
Journal: Cell Growth Differ
Title: Differential expression of MEK1 and MEK2 during mouse development.
Volume: 8
Issue: 5
Pages: 505-11
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9440696 | J:45333
First Author: Hemesath TJ
Year: 1998
Journal: Nature
Title: MAP kinase links the transcription factor Microphthalmia to c-Kit signalling in melanocytes.
Volume: 391
Issue: 6664
Pages: 298-301
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15240686 | J:91922
First Author: Laurent MN
Year: 2004
Journal: J Immunol
Title: Kinase suppressor of Ras couples Ras to the ERK cascade during T cell development.
Volume: 173
Issue: 2
Pages: 986-92
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15890671 | J:100430
First Author: Roberson MS
Year: 2005
Journal: Mol Endocrinol
Title: Gonadotropin-releasing hormone induction of extracellular-signal regulated kinase is blocked by inhibition of calmodulin.
Volume: 19
Issue: 9
Pages: 2412-23
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Publication
19038858 | J:146080
First Author: Schulz LC
Year: 2009
Journal: Biol Reprod
Title: Effect of leptin on mouse trophoblast giant cells.
Volume: 80
Issue: 3
Pages: 415-24
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8631303 | J:169818
First Author: Salmeron A
Year: 1996
Journal: EMBO J
Title: Activation of MEK-1 and SEK-1 by Tpl-2 proto-oncoprotein, a novel MAP kinase kinase kinase.
Volume: 15
Issue: 4
Pages: 817-26
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Publication
19628790 | J:169976
First Author: van Wijk B
Year: 2009
Journal: Circ Res
Title: Epicardium and myocardium separate from a common precursor pool by crosstalk between bone morphogenetic protein- and fibroblast growth factor-signaling pathways.
Volume: 105
Issue: 5
Pages: 431-41
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Publication
21498542 | J:182948
First Author: Meissner JD
Year: 2011
Journal: Nucleic Acids Res
Title: Extracellular signal-regulated kinase 1/2-mediated phosphorylation of p300 enhances myosin heavy chain I/beta gene expression via acetylation of nuclear factor of activated T cells c1.
Volume: 39
Issue: 14
Pages: 5907-25
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Publication
23055494 | J:190906
First Author: Yamamoto Y
Year: 2012
Journal: J Neurosci
Title: Raf kinase inhibitory protein is required for cerebellar long-term synaptic depression by mediating PKC-dependent MAPK activation.
Volume: 32
Issue: 41
Pages: 14254-64
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