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Search results 401 to 500 out of 509 for Cd2ap

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Hits by Strain

Hits by Category

Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:3821034
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2772126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5540557
Age: embryonic day 17.5
Image: GUDMAP:14430
Specimen Label: GUDMAP:14430
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3821034
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2772128
Stage: TS28
Assay Id: MGI:5540557
Age: postnatal day 84
Image: GUDMAP:14431
Specimen Label: GUDMAP:14431
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6287803
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-06
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1657719
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6515611
Age: embryonic day 11.0
Specimen Label: 4B
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
   
Probe: MGI:6287803
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1657718
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:6515611
Age: embryonic day 11.0
Specimen Label: not shown
Detected: true
Specimen Num: 31
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GXD Expression
GXD Expression
   
Probe: MGI:6287803
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3683828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6515611
Age: postnatal adult
Specimen Label: 5E
Detected: true
Specimen Num: 18
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GXD Expression
GXD Expression
   
Probe: MGI:6287803
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3683823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6515611
Age: embryonic day 15.0
Specimen Label: not shown
Detected: true
Specimen Num: 32
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GXD Expression
GXD Expression
   
Probe: MGI:6287803
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3683825
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6515611
Age: embryonic day 17.0
Specimen Label: not shown
Detected: true
Specimen Num: 33
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GXD Expression
GXD Expression
   
Probe: MGI:6287803
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-06
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3703825
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6515611
Age: embryonic day 17.0
Specimen Label: 6B
Detected: true
Specimen Num: 24
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GXD Expression
GXD Expression
   
Probe: MGI:6287803
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-06
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3808225
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6515611
Age: embryonic day 17.0
Specimen Label: 6A
Detected: true
Specimen Num: 23
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GXD Expression
GXD Expression
 
Probe: MGI:6287803
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3810028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6515611
Age: postnatal adult
Note: Expressed in the endothelial cells.
Specimen Label: not shown
Detected: true
Specimen Num: 34
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Publication
9741631 | J:49585
First Author: Dustin ML
Year: 1998
Journal: Cell
Title: A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts.
Volume: 94
Issue: 5
Pages: 667-77
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Publication
24598802 | J:210519
First Author: Casalena G
Year: 2014
Journal: Am J Physiol Renal Physiol
Title: Mpv17 in mitochondria protects podocytes against mitochondrial dysfunction and apoptosis in vivo and in vitro.
Volume: 306
Issue: 11
Pages: F1372-80
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Publication
27531950 | J:246082
First Author: Teng B
Year: 2016
Journal: Diabetes
Title: CIN85 Deficiency Prevents Nephrin Endocytosis and Proteinuria in Diabetes.
Volume: 65
Issue: 12
Pages: 3667-3679
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Publication
9365514 | J:43777
First Author: Jansson S
Year: 1997
Journal: J Cell Physiol
Title: Mouse metanephric kidney as a model system for identifying developmentally regulated genes.
Volume: 173
Issue: 2
Pages: 147-51
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Publication
14623103 | J:86362
First Author: Tarttelin EE
Year: 2003
Journal: FEBS Lett
Title: Neuropsin (Opn5): a novel opsin identified in mammalian neural tissue.
Volume: 554
Issue: 3
Pages: 410-6
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Publication
31461442 | J:284310
First Author: Potter AS
Year: 2019
Journal: PLoS One
Title: A bigenic mouse model of FSGS reveals perturbed pathways in podocytes, mesangial cells and endothelial cells.
Volume: 14
Issue: 8
Pages: e0216261
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Publication
30723173 | J:284383
 
First Author: Kong MS
Year: 2019
Journal: Sci Signal
Title: Inhibition of T cell activation and function by the adaptor protein CIN85.
Volume: 12
Issue: 567
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Publication
28916834 | J:255555
First Author: Tsuji K
Year: 2017
Journal: Sci Rep
Title: Ultrastructural Characterization of the Glomerulopathy in Alport Mice by Helium Ion Scanning Microscopy (HIM).
Volume: 7
Issue: 1
Pages: 11696
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Publication
26901816 | J:232418
First Author: Yu H
Year: 2016
Journal: J Clin Invest
Title: A role for genetic susceptibility in sporadic focal segmental glomerulosclerosis.
Volume: 126
Issue: 3
Pages: 1067-78
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Publication
17606992 | J:124215
First Author: Gaidos G
Year: 2007
Journal: J Cell Sci
Title: Structure and function analysis of the CMS/CIN85 protein family identifies actin-bundling properties and heterotypic-complex formation.
Volume: 120
Issue: Pt 14
Pages: 2366-77
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Publication
12559036 | J:230359
First Author: Cormont M
Year: 2003
Journal: Traffic
Title: CD2AP/CMS regulates endosome morphology and traffic to the degradative pathway through its interaction with Rab4 and c-Cbl.
Volume: 4
Issue: 2
Pages: 97-112
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Publication
17056598 | J:117677
First Author: Liu G
Year: 2006
Journal: J Biol Chem
Title: ZHX proteins regulate podocyte gene expression during the development of nephrotic syndrome.
Volume: 281
Issue: 51
Pages: 39681-92
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Publication
18328474 | J:135414
First Author: Pozzi A
Year: 2008
Journal: Dev Biol
Title: Beta1 integrin expression by podocytes is required to maintain glomerular structural integrity.
Volume: 316
Issue: 2
Pages: 288-301
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Publication
15965785 | J:99319
First Author: Kim EH
Year: 2005
Journal: Mamm Genome
Title: Quantitative trait loci for proteinuria in the focal glomerulosclerosis mouse model.
Volume: 16
Issue: 4
Pages: 242-50
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Publication
16886065 | J:113125
First Author: Jarad G
Year: 2006
Journal: J Clin Invest
Title: Proteinuria precedes podocyte abnormalities inLamb2-/- mice, implicating the glomerular basement membrane as an albumin barrier.
Volume: 116
Issue: 8
Pages: 2272-9
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Publication
12397035 | J:103379
First Author: Schiffer M
Year: 2002
Journal: J Am Soc Nephrol
Title: Inhibitory smads and tgf-Beta signaling in glomerular cells.
Volume: 13
Issue: 11
Pages: 2657-66
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Publication
24376653 | J:211125
First Author: Xiao Z
Year: 2013
Journal: PLoS One
Title: Wtip- and gadd45a-interacting protein dendrin is not crucial for the development or maintenance of the glomerular filtration barrier.
Volume: 8
Issue: 12
Pages: e83133
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Publication
25730372 | J:221043
First Author: Fukusumi Y
Year: 2015
Journal: Lab Invest
Title: SV2B is essential for the integrity of the glomerular filtration barrier.
Volume: 95
Issue: 5
Pages: 534-45
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Publication
27474268 | J:239186
First Author: Voisinne G
Year: 2016
Journal: Mol Syst Biol
Title: Co-recruitment analysis of the CBL and CBLB signalosomes in primary T cells identifies CD5 as a key regulator of TCR-induced ubiquitylation.
Volume: 12
Issue: 7
Pages: 876
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Publication
25962121 | J:228459
First Author: Schiffer M
Year: 2015
Journal: Nat Med
Title: Pharmacological targeting of actin-dependent dynamin oligomerization ameliorates chronic kidney disease in diverse animal models.
Volume: 21
Issue: 6
Pages: 601-9
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Publication
20576809 | J:185927
First Author: Wu F
Year: 2010
Journal: J Am Soc Nephrol
Title: Anion exchanger 1 interacts with nephrin in podocytes.
Volume: 21
Issue: 9
Pages: 1456-67
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Publication
31878951 | J:341565
First Author: Pandey RS
Year: 2019
Journal: Mol Neurodegener
Title: Genetic perturbations of disease risk genes in mice capture transcriptomic signatures of late-onset Alzheimer's disease.
Volume: 14
Issue: 1
Pages: 50
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Publication
26076477 | J:233807
First Author: Schell C
Year: 2015
Journal: PLoS One
Title: Podocyte-Specific Deletion of Murine CXADR Does Not Impair Podocyte Development, Function or Stress Response.
Volume: 10
Issue: 6
Pages: e0129424
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Publication
25993318 | J:316994
First Author: Lefebvre J
Year: 2015
Journal: Kidney Int
Title: Alternatively spliced isoforms of WT1 control podocyte-specific gene expression.
Volume: 88
Issue: 2
Pages: 321-31
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Publication
15924139 | J:99306
First Author: Reiser J
Year: 2005
Journal: Nat Genet
Title: TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function.
Volume: 37
Issue: 7
Pages: 739-44
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Publication
17283187 | J:119735
First Author: Cullen SP
Year: 2007
Journal: J Cell Biol
Title: Human and murine granzyme B exhibit divergent substrate preferences.
Volume: 176
Issue: 4
Pages: 435-44
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Publication
12217315 | J:78764
First Author: Sadl V
Year: 2002
Journal: Dev Biol
Title: The mouse Kreisler (Krml1/MafB) segmentation gene is required for differentiation of glomerular visceral epithelial cells.
Volume: 249
Issue: 1
Pages: 16-29
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Publication
18046313 | J:147670
First Author: Doné SC
Year: 2008
Journal: Kidney Int
Title: Nephrin is involved in podocyte maturation but not survival during glomerular development.
Volume: 73
Issue: 6
Pages: 697-704
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Publication
21406566 | J:182970
First Author: Saarikangas J
Year: 2011
Journal: J Cell Sci
Title: Missing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia.
Volume: 124
Issue: Pt 8
Pages: 1245-55
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Publication
27575556 | J:309992
First Author: Vasilopoulou E
Year: 2016
Journal: Kidney Int
Title: Loss of endogenous thymosin β4 accelerates glomerular disease.
Volume: 90
Issue: 5
Pages: 1056-1070
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Publication
38310234 | J:345099
First Author: Wang X
Year: 2024
Journal: BMC Genomics
Title: Identification and analysis of key circRNAs in the mouse embryonic ovary provides insight into primordial follicle development.
Volume: 25
Issue: 1
Pages: 139
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Publication
26142281 | J:224530
First Author: Dietrich JE
Year: 2015
Journal: EMBO Rep
Title: Venus trap in the mouse embryo reveals distinct molecular dynamics underlying specification of first embryonic lineages.
Volume: 16
Issue: 8
Pages: 1005-21
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Publication
31062503 | J:288722
First Author: Nilsson D
Year: 2019
Journal: Physiol Rep
Title: Foxc2 is essential for podocyte function.
Volume: 7
Issue: 9
Pages: e14083
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Publication
16498405 | J:106710
First Author: Takemoto M
Year: 2006
Journal: EMBO J
Title: Large-scale identification of genes implicated in kidney glomerulus development and function.
Volume: 25
Issue: 5
Pages: 1160-74
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Publication
16319116 | J:104891
First Author: Osafune K
Year: 2006
Journal: Development
Title: Identification of multipotent progenitors in the embryonic mouse kidney by a novel colony-forming assay.
Volume: 133
Issue: 1
Pages: 151-61
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Publication
23793062 | J:205441
First Author: Liang Y
Year: 2013
Journal: Nat Immunol
Title: The lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells.
Volume: 14
Issue: 8
Pages: 858-66
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Publication
- | J:101977
     
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
19334288 | J:148410
First Author: Combes AN
Year: 2009
Journal: Dev Dyn
Title: Three-dimensional visualization of testis cord morphogenesis, a novel tubulogenic mechanism in development.
Volume: 238
Issue: 5
Pages: 1033-41
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Publication
18554416 | J:139177
First Author: Hoffman BG
Year: 2008
Journal: Genome Biol
Title: Identification of transcripts with enriched expression in the developing and adult pancreas.
Volume: 9
Issue: 6
Pages: R99
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
19359362 | -
First Author: Ortega-Roldan JL
Year: 2009
Journal: Nucleic Acids Res
Title: Accurate characterization of weak macromolecular interactions by titration of NMR residual dipolar couplings: application to the CD2AP SH3-C:ubiquitin complex.
Volume: 37
Issue: 9
Pages: e70
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Allele
Cd2ap<em1Adiuj> | MGI:6446952
Name: CD2-associated protein; endonuclease-mediated mutation 1, MODEL-AD Center
Allele Type: Endonuclease-mediated
Attribute String: Not Specified
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DO Term
DOID:0112245 | focal segmental glomerulosclerosis 3
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Allele
Cd2ap<em1Smoc> | MGI:7288803
Name: CD2-associated protein; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Publication
21460840 | -
First Author: Hollingworth P
Year: 2011
Journal: Nat Genet
Title: Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.
Volume: 43
Issue: 5
Pages: 429-35
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Protein Domain
IPR035777 | CD2AP_SH3_3
Type: Domain
Description: CD2AP is a multifunctional adaptor protein involved in membrane trafficking, dynamic actin remodelling and endocytosis [, ]. CD2AP contains three SH3 domains, a proline-rich region, and a C-terminal coiled-coil domain. Different biological processes regulated by CD2AP require specific binding partners [].This entry represents the third SH3 domain (SH3C) of CD2AP. SH3C has been shown to bind ubiquitin [].
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Allele
Cd2ap<em1Irgu> | MGI:6476759
Name: CD2-associated protein; endonuclease-mediated mutation 1, Indra R Gupta
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence
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Publication
17020880 | -
First Author: Moncalián G
Year: 2006
Journal: J Biol Chem
Title: Atypical polyproline recognition by the CMS N-terminal Src homology 3 domain.
Volume: 281
Issue: 50
Pages: 38845-53
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Protein Domain
IPR035775 | CD2AP_SH3_1
Type: Domain
Description: CD2AP is a multifunctional adaptor protein involved in membrane trafficking, dynamic actin remodelling and endocytosis [, ]. CD2AP contains three SH3 domains, a proline-rich region, and a C-terminal coiled-coil domain. Different biological processes regulated by CD2AP require specific binding partners [].This entry represents the first SH3 domain (SH3A). It binds to the PXXXPR motif present in c-Cbl and the cytoplasmic domain of cell adhesion protein CD2 [].
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Protein Domain
IPR035776 | CD2AP_SH_2
Type: Domain
Description: CD2AP is a multifunctional adaptor protein involved in membrane trafficking, dynamic actin remodelling and endocytosis [, ]. CD2AP contains three SH3 domains, a proline-rich region, and a C-terminal coiled-coil domain. Different biological processes regulated by CD2AP require specific binding partners [].This entry represents the second SH3 domain (SH3B) of CD2AP. SH3B binds to c-Cbl in a site (TPSSRPLR is the core binding motif) distinct from the c-Cbl/SH3A binding site [].
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Publication
26296892 | -
First Author: Rouka E
Year: 2015
Journal: J Biol Chem
Title: Differential Recognition Preferences of the Three Src Homology 3 (SH3) Domains from the Adaptor CD2-associated Protein (CD2AP) and Direct Association with Ras and Rab Interactor 3 (RIN3).
Volume: 290
Issue: 42
Pages: 25275-92
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Publication
12530983 | -
First Author: Badour K
Year: 2003
Journal: Immunity
Title: The Wiskott-Aldrich syndrome protein acts downstream of CD2 and the CD2AP and PSTPIP1 adaptors to promote formation of the immunological synapse.
Volume: 18
Issue: 1
Pages: 141-54
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Genotype
Genotype
Symbol: Cd2ap/Cd2ap
Background: C57BL/6-Cd2ap
Zygosity: hm
Has Mutant Allele: true
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Strain
MGI:6770632 | C57BL/6J-Cd2ap<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:6446953 | B6.Cg-Apoe<tm1.1(APOE*4)Adiuj> App<em1Adiuj> Cd2ap<em1Adiuj> Trem2<em1Adiuj>/J
Attribute String: congenic, endonuclease-mediated mutation, mutant strain, targeted mutation
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