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Search results 201 to 269 out of 269 for Gch1

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Type Details Score
Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:72247
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Gch1<em1Ypt> | MGI:6474002
Name: GTP cyclohydrolase 1; endonuclease-mediated mutation 1, Ya-ping Tang
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence
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Allele
Gch1<tm1Smoc> | MGI:7289844
Name: GTP cyclohydrolase 1; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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DO Term
DOID:0112225 | BH4-deficient hyperphenylalaninemia B
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Genotype
Genotype
Symbol: Gch1/Gch1
Background: C57BL/6-Gch1
Zygosity: hm
Has Mutant Allele: true
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Allele
hph1 | MGI:1856903
 
Name: hyperphenylalaninemia 1
Allele Type: Chemically induced (ENU)
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Allele
Tg(Gch1-EGFP)GU68Gsat | MGI:4847074
Name: transgene insertion GU68, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
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Publication
3335865 | J:8982
First Author: McDonald JD
Year: 1988
Journal: J Neurochem
Title: Biochemical defect of the hph-1 mouse mutant is a deficiency in GTP-cyclohydrolase activity.
Volume: 50
Issue: 2
Pages: 655-7
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Publication
28874201 | J:280146
First Author: Rivera JC
Year: 2017
Journal: J Neuroinflammation
Title: Tetrahydrobiopterin (BH4) deficiency is associated with augmented inflammation and microvascular degeneration in the retina.
Volume: 14
Issue: 1
Pages: 181
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Publication
3360305 | J:9146
First Author: Bode VC
Year: 1988
Journal: Genetics
Title: hph-1: a mouse mutant with hereditary hyperphenylalaninemia induced by ethylnitrosourea mutagenesis.
Volume: 118
Issue: 2
Pages: 299-305
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Publication
8764604 | J:34167
First Author: Hyland K
Year: 1996
Journal: J Neurochem
Title: Tetrahydrobiopterin and biogenic amine metabolism in the hph-1 mouse.
Volume: 67
Issue: 2
Pages: 752-9
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Publication
23639814 | J:202783
First Author: Welsh C
Year: 2013
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Tetrahydrobiopterin deficiency induces gastroparesis in newborn mice.
Volume: 305
Issue: 1
Pages: G47-57
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Publication
8905183 | J:35898
First Author: Brand MP
Year: 1996
Journal: Brain Res
Title: Impairment of the nitric oxide/cyclic GMP pathway in cerebellar slices prepared from the hph-1 mouse.
Volume: 735
Issue: 1
Pages: 169-72
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Publication
22784235 | J:187618
First Author: Santhanam AV
Year: 2012
Journal: J Neurochem
Title: Uncoupling of eNOS causes superoxide anion production and impairs NO signaling in the cerebral microvessels of hph-1 mice.
Volume: 122
Issue: 6
Pages: 1211-8
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Publication
15774769 | J:104764
First Author: Wang CH
Year: 2005
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Tetrahydrobiopterin deficiency exaggerates intimal hyperplasia after vascular injury.
Volume: 289
Issue: 2
Pages: R299-304
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Publication
19560382 | J:155030
First Author: Gunasekera RS
Year: 2009
Journal: Mol Genet Metab
Title: In vivo regulation of phenylalanine hydroxylase in the genetic mutant hph-1 mouse model.
Volume: 98
Issue: 3
Pages: 264-72
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Publication
22982594 | J:193576
 
First Author: Santhanam AV
Year: 2012
Journal: Brain Res
Title: PPARδ agonist GW501516 prevents uncoupling of endothelial nitric oxide synthase in cerebral microvessels of hph-1 mice.
Volume: 1483
Pages: 89-95
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Publication
15144277 | J:101792
First Author: Abel RM
Year: 2004
Journal: Anat Histol Embryol
Title: A histological study of the hph-1 mouse mutant: an animal model of phenylketonuria and infantile hypertrophic pyloric stenosis.
Volume: 33
Issue: 3
Pages: 125-30
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Publication
8769878 | J:31922
First Author: Brand MP
Year: 1996
Journal: J Neurochem
Title: Neurochemical effects following peripheral administration of tetrahydropterin derivatives to the hph-1 mouse.
Volume: 66
Issue: 3
Pages: 1150-6
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Publication
21402147 | J:172078
First Author: Crabtree MJ
Year: 2011
Journal: Free Radic Biol Med
Title: Dihydrofolate reductase protects endothelial nitric oxide synthase from uncoupling in tetrahydrobiopterin deficiency.
Volume: 50
Issue: 11
Pages: 1639-46
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Publication
28079055 | J:254598
 
First Author: Belik J
Year: 2017
Journal: Sci Rep
Title: Intestinal microbiota as a tetrahydrobiopterin exogenous source in hph-1 mice.
Volume: 7
Pages: 39854
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Publication
15824200 | J:109691
First Author: Khoo JP
Year: 2005
Journal: Circulation
Title: Pivotal role for endothelial tetrahydrobiopterin in pulmonary hypertension.
Volume: 111
Issue: 16
Pages: 2126-33
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Publication
38042898 | J:343495
First Author: Edgar KS
Year: 2023
Journal: Sci Rep
Title: BH4 supplementation reduces retinal cell death in ischaemic retinopathy.
Volume: 13
Issue: 1
Pages: 21292
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Publication
7542713 | J:29110
First Author: Brand MP
Year: 1995
Journal: J Inherit Metab Dis
Title: Tetrahydrobiopterin deficiency and brain nitric oxide synthase in the hph1 mouse.
Volume: 18
Issue: 1
Pages: 33-9
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Publication
10984661 | J:102681
 
First Author: Maeda T
Year: 2000
Journal: Brain Dev
Title: Studies on the genotype-phenotype relation in the hph-1 mouse mutant deficient in guanosine triphosphate (GTP) cyclohydrolase I activity.
Volume: 22 Suppl 1
Pages: S50-3
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Publication
22083158 | J:280205
First Author: Gao L
Year: 2012
Journal: Hypertension
Title: Role of uncoupled endothelial nitric oxide synthase in abdominal aortic aneurysm formation: treatment with folic acid.
Volume: 59
Issue: 1
Pages: 158-66
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Publication
25218564 | J:217509
 
First Author: Nasser A
Year: 2014
Journal: Neurosci Res
Title: Anxiety- and depression-like phenotype of hph-1 mice deficient in tetrahydrobiopterin.
Volume: 89
Pages: 44-53
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Publication
3340448 | J:218444
First Author: McDonald JD
Year: 1988
Journal: Pediatr Res
Title: Hyperphenylalaninemia in the hph-1 mouse mutant.
Volume: 23
Issue: 1
Pages: 63-7
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Strain
MGI:5003636 | STOCK Tg(Gch1-EGFP)GU68Gsat/Mmucd
Attribute String: mutant stock, transgenic
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Allele
Tg(CAG-GCH1)#Wlf | MGI:6269989
Name: transgene insertion, Clifford J Woolf
Allele Type: Transgenic
Attribute String: Conditional ready, Epitope tag, Humanized sequence, Inserted expressed sequence
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Genotype
Genotype
Symbol: hph1/hph1
Background: involves: C57BL/6 * CBA/Ca
Zygosity: hm
Has Mutant Allele: true
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Publication
28469071 | J:288591
 
First Author: Oguri Y
Year: 2017
Journal: JCI Insight
Title: Tetrahydrobiopterin activates brown adipose tissue and regulates systemic energy metabolism.
Volume: 2
Issue: 9
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Publication
28596000 | J:252749
First Author: Xue J
Year: 2017
Journal: J Invest Dermatol
Title: The Nrf2/GCH1/BH4 Axis Ameliorates Radiation-Induced Skin Injury by Modulating the ROS Cascade.
Volume: 137
Issue: 10
Pages: 2059-2068
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Publication
27765794 | J:260783
First Author: Li P
Year: 2016
Journal: Circulation
Title: Inhibition of Aberrant MicroRNA-133a Expression in Endothelial Cells by Statin Prevents Endothelial Dysfunction by Targeting GTP Cyclohydrolase 1 in Vivo.
Volume: 134
Issue: 22
Pages: 1752-1765
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Publication
36044597 | J:330137
First Author: Cronin SJF
Year: 2022
Journal: Sci Transl Med
Title: Phenotypic drug screen uncovers the metabolic GCH1/BH4 pathway as key regulator of EGFR/KRAS-mediated neuropathic pain and lung cancer.
Volume: 14
Issue: 660
Pages: eabj1531
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Publication
30847343 | J:283155
 
First Author: Perhal A
Year: 2019
Journal: Front Med (Lausanne)
Title: Increased Reactive Oxygen Species Generation Contributes to the Atherogenic Activity of the B2 Bradykinin Receptor.
Volume: 6
Pages: 32
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Publication
25639845 | J:221429
 
First Author: Avriyanti E
Year: 2015
Journal: Neurosci Res
Title: Functional redundancy of protein kinase D1 and protein kinase D2 in neuronal polarity.
Volume: 95
Pages: 12-20
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Publication
24951762 | J:247930
First Author: Lai YC
Year: 2014
Journal: Circ Res
Title: Pulmonary arterial hypertension: the clinical syndrome.
Volume: 115
Issue: 1
Pages: 115-30
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Publication
- | J:100256
     
First Author: The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY)
Year: 2005
Journal: Database Download
Title: MGI download of GENSAT transgene data
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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