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Search results 601 to 686 out of 686 for Mdm2

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Category: Publication
Type Details Score
Publication
First Author: Inga A
Year: 2002
Journal: Oncogene
Title: A novel p53 mutational hotspot in skin tumors from UV-irradiated Xpc mutant mice alters transactivation functions.
Volume: 21
Issue: 37
Pages: 5704-15
Publication
First Author: Xu D
Year: 2002
Journal: EMBO J
Title: Ets1 is required for p53 transcriptional activity in UV-induced apoptosis in embryonic stem cells.
Volume: 21
Issue: 15
Pages: 4081-93
Publication
First Author: Melnikova VO
Year: 2003
Journal: Oncogene
Title: Mutant p53 is constitutively phosphorylated at Serine 15 in UV-induced mouse skin tumors: involvement of ERK1/2 MAP kinase.
Volume: 22
Issue: 38
Pages: 5958-66
Publication
First Author: Gottlieb E
Year: 1997
Journal: EMBO J
Title: Transgenic mouse model for studying the transcriptional activity of the p53 protein: age- and tissue-dependent changes in radiation-induced activation during embryogenesis.
Volume: 16
Issue: 6
Pages: 1381-90
Publication  
First Author: Youssef JA
Year: 2003
Journal: Mol Cancer
Title: Hepatocarcinogenic potential of the glucocorticoid antagonist RU486 in B6C3F1 mice: effect on apoptosis, expression of oncogenes and the tumor suppressor gene p53.
Volume: 2
Pages: 3
Publication
First Author: Dudgeon C
Year: 2006
Journal: Cancer Res
Title: Tumor susceptibility and apoptosis defect in a mouse strain expressing a human p53 transgene.
Volume: 66
Issue: 6
Pages: 2928-36
Publication
First Author: Tang J
Year: 2006
Journal: Nat Cell Biol
Title: Critical role for Daxx in regulating Mdm2.
Volume: 8
Issue: 8
Pages: 855-62
Publication
First Author: Aizu W
Year: 2006
Journal: Biochem Pharmacol
Title: Circumvention and reactivation of the p53 oncogene checkpoint in mouse colon tumors.
Volume: 72
Issue: 8
Pages: 981-91
Publication
First Author: Xue SA
Year: 2008
Journal: Immunology
Title: Generation and characterization of transgenic mice expressing a T-cell receptor specific for the tumour-associated antigen MDM2.
Volume: 124
Issue: 3
Pages: 315-21
Publication
First Author: Cuesta A
Year: 2009
Journal: Biochem J
Title: The tumour suppressor p53 regulates the expression of amyloid precursor protein (APP).
Volume: 418
Issue: 3
Pages: 643-50
Publication
First Author: Feng Z
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Chronic restraint stress attenuates p53 function and promotes tumorigenesis.
Volume: 109
Issue: 18
Pages: 7013-8
Publication
First Author: Bae S
Year: 2012
Journal: FEBS Lett
Title: TRIAD1 inhibits MDM2-mediated p53 ubiquitination and degradation.
Volume: 586
Issue: 19
Pages: 3057-63
Publication
First Author: Pal D
Year: 2012
Journal: Carcinogenesis
Title: Prevention of liver carcinogenesis by amarogentin through modulation of G1/S cell cycle check point and induction of apoptosis.
Volume: 33
Issue: 12
Pages: 2424-31
Publication
First Author: Liu Y
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Overexpression of gankyrin in mouse hepatocytes induces hemangioma by suppressing factor inhibiting hypoxia-inducible factor-1 (FIH-1) and activating hypoxia-inducible factor-1.
Volume: 432
Issue: 1
Pages: 22-7
Publication  
First Author: Wang A J
Year: 2022
Journal: Redox Biol
Title: Cardiac SIRT1 ameliorates doxorubicin-induced cardiotoxicity by targeting sestrin 2.
Volume: 52
Pages: 102310
Publication
First Author: He G
Year: 2014
Journal: Mol Cell Biol
Title: AMP-activated protein kinase induces p53 by phosphorylating MDMX and inhibiting its activity.
Volume: 34
Issue: 2
Pages: 148-57
Publication
First Author: Fornari F
Year: 2014
Journal: Mol Cancer Res
Title: p53/mdm2 feedback loop sustains miR-221 expression and dictates the response to anticancer treatments in hepatocellular carcinoma.
Volume: 12
Issue: 2
Pages: 203-16
Publication
First Author: Leeper NJ
Year: 2013
Journal: Arterioscler Thromb Vasc Biol
Title: Loss of CDKN2B promotes p53-dependent smooth muscle cell apoptosis and aneurysm formation.
Volume: 33
Issue: 1
Pages: e1-e10
Publication
First Author: Inoue K
Year: 2016
Journal: Int J Cancer
Title: Transcription factors that interact with p53 and Mdm2.
Volume: 138
Issue: 7
Pages: 1577-85
Publication
First Author: Aiken J
Year: 2016
Journal: FASEB J
Title: Phosphorylation of murine double minute-2 on Ser166 is downstream of VEGF-A in exercised skeletal muscle and regulates primary endothelial cell migration and FoxO gene expression.
Volume: 30
Issue: 3
Pages: 1120-34
Publication
First Author: Barabutis N
Year: 2015
Journal: Am J Physiol Lung Cell Mol Physiol
Title: p53 protects against LPS-induced lung endothelial barrier dysfunction.
Volume: 308
Issue: 8
Pages: L776-87
Publication
First Author: Mulay SR
Year: 2016
Journal: Am J Pathol
Title: Murine Double Minute-2 Inhibition Ameliorates Established Crescentic Glomerulonephritis.
Volume: 186
Issue: 6
Pages: 1442-53
Publication
First Author: Wu G
Year: 2014
Journal: Circulation
Title: LincRNA-p21 regulates neointima formation, vascular smooth muscle cell proliferation, apoptosis, and atherosclerosis by enhancing p53 activity.
Volume: 130
Issue: 17
Pages: 1452-1465
Publication
First Author: Inoue K
Year: 2016
Journal: Int J Cancer
Title: Aberrant splicing of the DMP1-ARF-MDM2-p53 pathway in cancer.
Volume: 139
Issue: 1
Pages: 33-41
Publication
First Author: Lahav-Baratz S
Year: 2017
Journal: Biochem Biophys Res Commun
Title: The testis-specific USP26 is a deubiquitinating enzyme of the ubiquitin ligase Mdm2.
Volume: 482
Issue: 1
Pages: 106-111
Publication
First Author: Boregowda SV
Year: 2017
Journal: Stem Cells
Title: IP6K1 Reduces Mesenchymal Stem/Stromal Cell Fitness and Potentiates High Fat Diet-Induced Skeletal Involution.
Volume: 35
Issue: 8
Pages: 1973-1983
Publication
First Author: Yu M
Year: 2016
Journal: PLoS One
Title: Exercise Activates p53 and Negatively Regulates IGF-1 Pathway in Epidermis within a Skin Cancer Model.
Volume: 11
Issue: 8
Pages: e0160939
Publication
First Author: Saison-Ridinger M
Year: 2017
Journal: PLoS One
Title: Reprogramming pancreatic stellate cells via p53 activation: A putative target for pancreatic cancer therapy.
Volume: 12
Issue: 12
Pages: e0189051
Publication
First Author: Miao SB
Year: 2017
Journal: Arterioscler Thromb Vasc Biol
Title: Accumulation of Smooth Muscle 22α Protein Accelerates Senescence of Vascular Smooth Muscle Cells via Stabilization of p53 In Vitro and In Vivo.
Volume: 37
Issue: 10
Pages: 1849-1859
Publication
First Author: Klimovich B
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Loss of p53 function at late stages of tumorigenesis confers ARF-dependent vulnerability to p53 reactivation therapy.
Volume: 116
Issue: 44
Pages: 22288-22293
Publication
First Author: Xu Y
Year: 2019
Journal: J Biol Chem
Title: Prolyl hydroxylase 3 stabilizes the p53 tumor suppressor by inhibiting the p53-MDM2 interaction in a hydroxylase-independent manner.
Volume: 294
Issue: 25
Pages: 9949-9958
Publication  
First Author: Singh S
Year: 2019
Journal: JCI Insight
Title: DNA replication in progenitor cells and epithelial regeneration after lung injury requires the oncoprotein MDM2.
Volume: 4
Issue: 20
Publication
First Author: Levine AJ
Year: 2020
Journal: Nat Rev Cancer
Title: p53: 800 million years of evolution and 40 years of discovery.
Volume: 20
Issue: 8
Pages: 471-480
Publication
First Author: Lees A
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: The pseudo-caspase FLIP(L) regulates cell fate following p53 activation.
Volume: 117
Issue: 30
Pages: 17808-17819
Publication
First Author: Lai YJ
Year: 2019
Journal: Aging Cell
Title: Estrogen receptor α promotes Cav1.2 ubiquitination and degradation in neuronal cells and in APP/PS1 mice.
Volume: 18
Issue: 4
Pages: e12961
Publication
First Author: Moyer SM
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: p53 drives a transcriptional program that elicits a non-cell-autonomous response and alters cell state in vivo.
Volume: 117
Issue: 38
Pages: 23663-23673
Publication
First Author: Zhu F
Year: 2021
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Tubular Numb promotes renal interstitial fibrosis via modulating HIF-1α protein stability.
Volume: 1867
Issue: 5
Pages: 166081
Publication
First Author: Xue Y
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Proteasome inhibitor bortezomib stabilizes and activates p53 in hematopoietic stem/progenitors and double-negative T cells in vivo.
Volume: 120
Issue: 13
Pages: e2219978120
Publication  
First Author: Huang Y
Year: 2024
Journal: Cells
Title: Alcohol Exposure Induces Nucleolar Stress and Apoptosis in Mouse Neural Stem Cells and Late-Term Fetal Brain.
Volume: 13
Issue: 5
Publication
First Author: Lentzen G
Year: 2003
Journal: Chem Biol
Title: Structural basis for contrasting activities of ribosome binding thiazole antibiotics.
Volume: 10
Issue: 8
Pages: 769-78
Publication
First Author: Jonker HR
Year: 2007
Journal: Nucleic Acids Res
Title: L11 domain rearrangement upon binding to RNA and thiostrepton studied by NMR spectroscopy.
Volume: 35
Issue: 2
Pages: 441-54
Publication
First Author: Jenvert RM
Year: 2007
Journal: J Mol Biol
Title: The flexible N-terminal domain of ribosomal protein L11 from Escherichia coli is necessary for the activation of stringent factor.
Volume: 365
Issue: 3
Pages: 764-72
Publication
First Author: Kasai K
Year: 2006
Journal: J Bacteriol
Title: Physiological analysis of the stringent response elicited in an extreme thermophilic bacterium, Thermus thermophilus.
Volume: 188
Issue: 20
Pages: 7111-22
Publication
First Author: Dai MS
Year: 2006
Journal: J Biol Chem
Title: Regulation of the MDM2-p53 pathway by ribosomal protein L11 involves a post-ubiquitination mechanism.
Volume: 281
Issue: 34
Pages: 24304-13
Publication
First Author: Bouakaz L
Year: 2006
Journal: J Biol Chem
Title: The role of ribosomal protein L11 in class I release factor-mediated translation termination and translational accuracy.
Volume: 281
Issue: 7
Pages: 4548-56
Publication
First Author: Bowen WS
Year: 2005
Journal: J Biol Chem
Title: Interaction of thiostrepton and elongation factor-G with the ribosomal protein L11-binding domain.
Volume: 280
Issue: 4
Pages: 2934-43
Publication
First Author: Bhat KP
Year: 2004
Journal: EMBO J
Title: Essential role of ribosomal protein L11 in mediating growth inhibition-induced p53 activation.
Volume: 23
Issue: 12
Pages: 2402-12
Publication
First Author: Zhong Z
Year: 2010
Journal: J Neurosci
Title: Protein S protects neurons from excitotoxic injury by activating the TAM receptor Tyro3-phosphatidylinositol 3-kinase-Akt pathway through its sex hormone-binding globulin-like region.
Volume: 30
Issue: 46
Pages: 15521-34
Publication
First Author: Hayano S
Year: 2015
Journal: Development
Title: Augmented BMP signaling in the neural crest inhibits nasal cartilage morphogenesis by inducing p53-mediated apoptosis.
Volume: 142
Issue: 7
Pages: 1357-67
Publication
First Author: Chapeau EA
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Resistance mechanisms to TP53-MDM2 inhibition identified by in vivo piggyBac transposon mutagenesis screen in an Arf-/- mouse model.
Volume: 114
Issue: 12
Pages: 3151-3156
Publication
First Author: Uo T
Year: 2007
Journal: J Neurosci
Title: Apoptotic actions of p53 require transcriptional activation of PUMA and do not involve a direct mitochondrial/cytoplasmic site of action in postnatal cortical neurons.
Volume: 27
Issue: 45
Pages: 12198-210
Publication
First Author: Comiskey DF Jr
Year: 2018
Journal: Oncogene
Title: A novel mouse model of rhabdomyosarcoma underscores the dichotomy of MDM2-ALT1 function in vivo.
Volume: 37
Issue: 1
Pages: 95-106
Publication
First Author: Yan W
Year: 2016
Journal: Genes Dev
Title: Mice deficient in poly(C)-binding protein 4 are susceptible to spontaneous tumors through increased expression of ZFP871 that targets p53 for degradation.
Volume: 30
Issue: 5
Pages: 522-34
Publication
First Author: Iida K
Year: 2007
Journal: Carcinogenesis
Title: Nrf2 and p53 cooperatively protect against BBN-induced urinary bladder carcinogenesis.
Volume: 28
Issue: 11
Pages: 2398-403
Publication
First Author: Nakamura K
Year: 2017
Journal: J Hepatol
Title: Macrophage heme oxygenase-1-SIRT1-p53 axis regulates sterile inflammation in liver ischemia-reperfusion injury.
Volume: 67
Issue: 6
Pages: 1232-1242
Publication
First Author: Sugihara T
Year: 2008
Journal: J Radiat Res
Title: Inverse dose-rate-effects on the expressions of extra-cellular matrix-related genes in low-dose-rate gamma-ray irradiated murine cells.
Volume: 49
Issue: 3
Pages: 231-40
Publication
First Author: Saldivar JC
Year: 2012
Journal: PLoS Genet
Title: Initiation of genome instability and preneoplastic processes through loss of Fhit expression.
Volume: 8
Issue: 11
Pages: e1003077
Publication
First Author: Zhuang S
Year: 2000
Journal: Mutat Res
Title: Genetic analysis of Raf1, Mdm2, c-Myc, Cdc25a and Cdc25b proto-oncogenes in 2',3'-dideoxycytidine- and 1,3-butadiene-induced lymphomas in B6C3F1 mice.
Volume: 452
Issue: 1
Pages: 19-26
Publication
First Author: Phelps M
Year: 2003
Journal: Cancer Res
Title: p53-independent activation of the hdm2-P2 promoter through multiple transcription factor response elements results in elevated hdm2 expression in estrogen receptor alpha-positive breast cancer cells.
Volume: 63
Issue: 10
Pages: 2616-23
Publication
First Author: Levav-Cohen Y
Year: 2005
Journal: Biochem Biophys Res Commun
Title: C-Abl as a modulator of p53.
Volume: 331
Issue: 3
Pages: 737-49
Publication
First Author: Martinelli VC
Year: 2014
Journal: PLoS One
Title: ZASP interacts with the mechanosensing protein Ankrd2 and p53 in the signalling network of striated muscle.
Volume: 9
Issue: 3
Pages: e92259
Publication  
First Author: Valentino T
Year: 2013
Journal: Cell Death Dis
Title: PATZ1 interacts with p53 and regulates expression of p53-target genes enhancing apoptosis or cell survival based on the cellular context.
Volume: 4
Pages: e963
Publication
First Author: Kooi IE
Year: 2017
Journal: Genes Chromosomes Cancer
Title: Genomic landscape of retinoblastoma in Rb-/- p130-/- mice resembles human retinoblastoma.
Volume: 56
Issue: 3
Pages: 231-242
Publication
First Author: García-Alai MM
Year: 2010
Journal: Protein Sci
Title: The structure of the FYR domain of transforming growth factor beta regulator 1.
Volume: 19
Issue: 7
Pages: 1432-8
Publication  
First Author: Kutle I
Year: 2020
Journal: J Virol
Title: Murine Cytomegalovirus M25 Proteins Sequester the Tumor Suppressor Protein p53 in Nuclear Accumulations.
Volume: 94
Issue: 20
Publication
First Author: Tiwari A
Year: 2020
Journal: Gastroenterology
Title: Loss of HIF1A From Pancreatic Cancer Cells Increases Expression of PPP1R1B and Degradation of p53 to Promote Invasion and Metastasis.
Volume: 159
Issue: 5
Pages: 1882-1897.e5
Publication
First Author: Prasad R
Year: 1997
Journal: Oncogene
Title: Structure and expression pattern of human ALR, a novel gene with strong homology to ALL-1 involved in acute leukemia and to Drosophila trithorax.
Volume: 15
Issue: 5
Pages: 549-60
Publication
First Author: Hsieh JJ
Year: 2003
Journal: Mol Cell Biol
Title: Proteolytic cleavage of MLL generates a complex of N- and C-terminal fragments that confers protein stability and subnuclear localization.
Volume: 23
Issue: 1
Pages: 186-94
Publication
First Author: Balciunas D
Year: 2000
Journal: Trends Biochem Sci
Title: Evidence of domain swapping within the jumonji family of transcription factors.
Volume: 25
Issue: 6
Pages: 274-6
Publication
First Author: Doerks T
Year: 2002
Journal: Genome Res
Title: Systematic identification of novel protein domain families associated with nuclear functions.
Volume: 12
Issue: 1
Pages: 47-56
Publication
First Author: Kavran JM
Year: 2007
Journal: J Mol Biol
Title: Structure of the base of the L7/L12 stalk of the Haloarcula marismortui large ribosomal subunit: analysis of L11 movements.
Volume: 371
Issue: 4
Pages: 1047-59
Publication
First Author: Galderisi U
Year: 2003
Journal: Oncogene
Title: Cell cycle regulation and neural differentiation.
Volume: 22
Issue: 33
Pages: 5208-19
Publication
First Author: Klein DJ
Year: 2004
Journal: J Mol Biol
Title: The roles of ribosomal proteins in the structure assembly, and evolution of the large ribosomal subunit.
Volume: 340
Issue: 1
Pages: 141-77
Publication
First Author: Choli T
Year: 1989
Journal: Biochem Int
Title: Structural properties of ribosomal protein L11 from Escherichia coli.
Volume: 19
Issue: 6
Pages: 1323-38
Publication
First Author: Pucciarelli MG
Year: 1990
Journal: Nucleic Acids Res
Title: The 26S rRNA binding ribosomal protein equivalent to bacterial protein L11 is encoded by unspliced duplicated genes in Saccharomyces cerevisiae.
Volume: 18
Issue: 15
Pages: 4409-16
Publication
First Author: Wimberly BT
Year: 1999
Journal: Cell
Title: A detailed view of a ribosomal active site: the structure of the L11-RNA complex.
Volume: 97
Issue: 4
Pages: 491-502
Publication
First Author: Demirci H
Year: 2007
Journal: EMBO J
Title: Recognition of ribosomal protein L11 by the protein trimethyltransferase PrmA.
Volume: 26
Issue: 2
Pages: 567-77
Publication
First Author: Harms JM
Year: 2008
Journal: Mol Cell
Title: Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin.
Volume: 30
Issue: 1
Pages: 26-38
Publication
First Author: Demirci H
Year: 2008
Journal: Structure
Title: Multiple-site trimethylation of ribosomal protein L11 by the PrmA methyltransferase.
Volume: 16
Issue: 7
Pages: 1059-66
Publication
First Author: Carninci P
Year: 2000
Journal: Genome Res
Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Volume: 10
Issue: 10
Pages: 1617-30
Publication  
First Author: Carninci P
Year: 1999
Journal: Methods Enzymol
Title: High-efficiency full-length cDNA cloning.
Volume: 303
Pages: 19-44
Publication
First Author: Shibata K
Year: 2000
Journal: Genome Res
Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Volume: 10
Issue: 11
Pages: 1757-71
Publication
First Author: Katayama S
Year: 2005
Journal: Science
Title: Antisense transcription in the mammalian transcriptome.
Volume: 309
Issue: 5740
Pages: 1564-6
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
Publication
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
Publication
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112