Type |
Details |
Score |
Allele |
Name: |
KAT8 regulatory NSL complex subunit 2; gene trap EUCE0042c08, Helmholtz Zentrum Muenchen GmbH |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 2; gene trap PST14410, Mammalian Functional Genomics Centre |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 2; gene trap E148E03, German Gene Trap Consortium |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 2; gene trap OST166201, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 2; targeted mutation 1a, Wellcome Trust Sanger Institute |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, Null/knockout, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 2; gene trap 333G10, Centre for Modeling Human Disease |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 2; gene trap E234D12, German Gene Trap Consortium |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 2, pseudogene; gene trap XP0296, Wellcome Trust Sanger Institute |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 3; gene trap E043B02, German Gene Trap Consortium |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 3; gene trap AY0031, Wellcome Trust Sanger Institute |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 3; gene trap OST174902, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 3; targeted mutation 1.1, Max Planck Institut fur Immunbiologie |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 3; gene trap EUCJ0136d08, Helmholtz Zentrum Muenchen GmbH |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1-like; targeted mutation 1a, Wellcome Trust Sanger Institute |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, Null/knockout, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1-like; gene trap OST235350, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1-like; targeted mutation 1b, Wellcome Trust Sanger Institute |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1-like; targeted mutation 1e, Wellcome Trust Sanger Institute |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Kansl3/Kansl3 |
Background: |
C57BL/6NJ-Kansl3/Mmjax |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Poorkaj P |
Year: |
2001 |
Journal: |
Mamm Genome |
Title: |
A genomic sequence analysis of the mouse and human microtubule-associated protein tau. |
Volume: |
12 |
Issue: |
9 |
Pages: |
700-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kadlec J |
Year: |
2011 |
Journal: |
Nat Struct Mol Biol |
Title: |
Structural basis for MOF and MSL3 recruitment into the dosage compensation complex by MSL1. |
Volume: |
18 |
Issue: |
2 |
Pages: |
142-9 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, targeted mutation |
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1; gene trap IST14746A5, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1; gene trap IST14086F11, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1; gene trap IST13983A11, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1; gene trap IST14745D3, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1; gene trap IST13199F11, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1; gene trap IST13290E2, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1; gene trap IST14906F12, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1; gene trap IST11638F10, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1; gene trap IST13305C9, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1; gene trap IST14274C8, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1; gene trap IST13895C9, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1; gene trap IST13779D9, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1; gene trap IST14605E6, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1; gene trap IST14644C12, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1; gene trap IST15014C11, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1; gene trap IST13201G11, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1; gene trap IST10728E7, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1; gene trap IST15014E9, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1; gene trap IST13787H3, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1; gene trap IST14615D10, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant strain, coisogenic, targeted mutation |
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1; gene trap IST11547H1, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1; gene trap IST15050G10, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1; gene trap IST10950A11, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1; gene trap IST14502A2, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1; gene trap IST11695G8, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1; gene trap IST13782D12, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1; gene trap IST14018H9, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1; gene trap IST14086E7, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1; gene trap IST13599H7, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1; gene trap IST13370F11, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1; gene trap Ayu21-W323, Institute of Molecular Embryology and Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1; gene trap IST13793C12, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1; gene trap IST13724C2, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 1; gene trap IST14652A9, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 2; gene trap IST14589G8, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 2; gene trap IST14575B6, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 2; gene trap IST13381D4, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 2; gene trap IST14678A5, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 2; gene trap IST14578C9, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 2; gene trap IST14166G9, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 2; gene trap IST15070C4, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
KAT8 regulatory NSL complex subunit 3; gene trap (LTOPG06), Research Institute for Microbial Diseases, Osaka University |
Allele Type: |
Gene trapped |
Attribute String: |
Reporter |
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant strain, coisogenic, gene trap |
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant strain, targeted mutation, coisogenic |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, targeted mutation |
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant strain, targeted mutation, coisogenic |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Kansl1/Mapt/Kansl1/Mapt |
Background: |
involves: C57BL/6 * C57BL/6J * C57BL/6JOlaHsd |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Kansl1l/Kansl1l |
Background: |
C57BL/6N-Kansl1l/Ieg |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Kansl2/Kansl2 |
Background: |
involves: C57BL/6 |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Kansl3/Kansl3 |
Background: |
involves: C57BL/6 |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Kansl1/Kansl1 |
Background: |
C57BL/6N-Kansl1/Ics |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Cai Y |
Year: |
2010 |
Journal: |
J Biol Chem |
Title: |
Subunit composition and substrate specificity of a MOF-containing histone acetyltransferase distinct from the male-specific lethal (MSL) complex. |
Volume: |
285 |
Issue: |
7 |
Pages: |
4268-72 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Kansl3/Kansl3 Tg(Nes-cre)1Kln/? |
Background: |
involves: C57BL/6N * SJL |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Kansl2/Kansl2 Tg(Nes-cre)1Kln/? |
Background: |
involves: C57BL/6 * SJL |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Kansl1/Kansl1<+> |
Background: |
C57BL/6N-Kansl1/Ics |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Dmitriev RI |
Year: |
2014 |
Journal: |
J Cell Biochem |
Title: |
Two distinct nuclear localization signals in mammalian MSL1 regulate its function. |
Volume: |
115 |
Issue: |
11 |
Pages: |
1967-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
MarÃn I |
Year: |
2003 |
Journal: |
J Mol Evol |
Title: |
Evolution of chromatin-remodeling complexes: comparative genomics reveals the ancient origin of "novel" compensasome genes. |
Volume: |
56 |
Issue: |
5 |
Pages: |
527-39 |
|
•
•
•
•
•
|
Publication |
First Author: |
Morales V |
Year: |
2004 |
Journal: |
EMBO J |
Title: |
Functional integration of the histone acetyltransferase MOF into the dosage compensation complex. |
Volume: |
23 |
Issue: |
11 |
Pages: |
2258-68 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This domain was first identified in drosophila MSL1 (male-specific lethal 1) []. In drosophila it binds to the histone acetyltransferase males-absent on the first protein (MOF) and to protein male-specific lethal-3 (MSL3) [, ]. This domain can also be found in KAT8 regulatory NSL complex subunit 1 (KANSL1 or NSL1), which is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Füllgrabe J |
Year: |
2013 |
Journal: |
Nature |
Title: |
The histone H4 lysine 16 acetyltransferase hMOF regulates the outcome of autophagy. |
Volume: |
500 |
Issue: |
7463 |
Pages: |
468-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nishiguchi S |
Year: |
1996 |
Journal: |
J Biochem |
Title: |
A catalogue of genes in mouse embryonal carcinoma F9 cells identified with expressed sequence tags. |
Volume: |
119 |
Issue: |
4 |
Pages: |
749-67 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This entry represents an α/β hydrolase-fold domain of the animal KAT8 regulatory NSL complex subunit 3 (KANSL3 or NSL3, also known as testis development protein PRTD) and the testis-expressed sequence 30 proteins.KAT8 regulatory NSL complex subunit 3 is part of the NSL complex that is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription []. The function of the testis-expressed sequence 30 protein is not known.This entry also includes uncharacterized bacterial proteins. |
|
•
•
•
•
•
|
Publication |
First Author: |
Kong M |
Year: |
2019 |
Journal: |
Redox Biol |
Title: |
Serum response factor (SRF) promotes ROS generation and hepatic stellate cell activation by epigenetically stimulating NCF1/2 transcription. |
Volume: |
26 |
|
Pages: |
101302 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
147
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
616
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Nakano Y |
Year: |
2012 |
Journal: |
PLoS Genet |
Title: |
A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. |
Volume: |
8 |
Issue: |
10 |
Pages: |
e1002966 |
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki N |
Year: |
2003 |
Journal: |
DNA Res |
Title: |
Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. |
Volume: |
10 |
Issue: |
4 |
Pages: |
167-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki N |
Year: |
2003 |
Journal: |
DNA Res |
Title: |
Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. |
Volume: |
10 |
Issue: |
1 |
Pages: |
35-48 |
|
•
•
•
•
•
|
Publication |
First Author: |
The RIKEN BioResource Center |
Year: |
2006 |
Journal: |
Unpublished |
Title: |
Information obtained from The RIKEN BioResource Center |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Araki K |
Year: |
1999 |
Journal: |
Cell Mol Biol (Noisy-le-grand) |
Title: |
Exchangeable gene trap using the Cre/mutated lox system. |
Volume: |
45 |
Issue: |
5 |
Pages: |
737-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Taniwaki T |
Year: |
2005 |
Journal: |
Dev Growth Differ |
Title: |
Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette. |
Volume: |
47 |
Issue: |
3 |
Pages: |
163-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory |
Year: |
2012 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by The Jackson Laboratory |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Blackshaw S |
Year: |
2004 |
Journal: |
PLoS Biol |
Title: |
Genomic analysis of mouse retinal development. |
Volume: |
2 |
Issue: |
9 |
Pages: |
E247 |
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Publication |
First Author: |
Park J |
Year: |
2013 |
Journal: |
Mol Cell |
Title: |
SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. |
Volume: |
50 |
Issue: |
6 |
Pages: |
919-30 |
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Publication |
First Author: |
International Knockout Mouse Consortium |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of modified allele data from IKMC and creation of new knockout alleles |
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Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
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Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data |
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