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Search results 1 to 100 out of 264 for Nr1h2

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Category: Publication
Type Details Score
Publication  
First Author: Michaels AJ
Year: 2021
Journal: J Exp Med
Title: Nuclear receptor LXRβ controls fitness and functionality of activated T cells.
Volume: 218
Issue: 4
Publication
First Author: Liu B
Year: 2008
Journal: J Lipid Res
Title: Genetic variations and treatments that affect the lifespan of the NPC1 mouse.
Volume: 49
Issue: 3
Pages: 663-9
Publication
First Author: Holm S
Year: 2010
Journal: Biochem Biophys Res Commun
Title: LXRbeta deficient mice have reduced hepatic insulin clearance during hyperinsulinemic euglucemic clamp.
Volume: 392
Issue: 3
Pages: 436-41
Publication
First Author: Xu P
Year: 2014
Journal: Mol Psychiatry
Title: Liver X receptor β is essential for the differentiation of radial glial cells to oligodendrocytes in the dorsal cortex.
Volume: 19
Issue: 8
Pages: 947-57
Publication
First Author: Dai YB
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Liver X receptor β protects dopaminergic neurons in a mouse model of Parkinson disease.
Volume: 109
Issue: 32
Pages: 13112-7
Publication
First Author: Tan XJ
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Anxiety in liver X receptor β knockout female mice with loss of glutamic acid decarboxylase in ventromedial prefrontal cortex.
Volume: 109
Issue: 19
Pages: 7493-8
Publication
First Author: Song XY
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Retinal and optic nerve degeneration in liver X receptor β knockout mice.
Volume: 116
Issue: 33
Pages: 16507-16512
Publication
First Author: Li N
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: LXR modulation blocks prostaglandin E2 production and matrix degradation in cartilage and alleviates pain in a rat osteoarthritis model.
Volume: 107
Issue: 8
Pages: 3734-9
Publication  
First Author: Wan YW
Year: 2021
Journal: Blood Cells Mol Dis
Title: LXRβ is involved in the control of platelet production from megakaryocytes.
Volume: 89
Pages: 102568
Publication
First Author: Hsu JJ
Year: 2009
Journal: FEBS Lett
Title: T0901317, an LXR agonist, augments PKA-induced vascular cell calcification.
Volume: 583
Issue: 8
Pages: 1344-8
Publication  
First Author: Fernández-de Frutos M
Year: 2019
Journal: Mol Cell Biol
Title: MicroRNA 7 Impairs Insulin Signaling and Regulates Aβ Levels through Posttranscriptional Regulation of the Insulin Receptor Substrate 2, Insulin Receptor, Insulin-Degrading Enzyme, and Liver X Receptor Pathway.
Volume: 39
Issue: 22
Publication
First Author: Hashimoto K
Year: 2009
Journal: Biochem Biophys Res Commun
Title: A liver X receptor (LXR)-beta alternative splicing variant (LXRBSV) acts as an RNA co-activator of LXR-beta.
Volume: 390
Issue: 4
Pages: 1260-5
Publication
First Author: Boussadia O
Year: 2003
Journal: J Virol
Title: Unr is required in vivo for efficient initiation of translation from the internal ribosome entry sites of both rhinovirus and poliovirus.
Volume: 77
Issue: 6
Pages: 3353-9
Publication
First Author: Saltel F
Year: 2017
Journal: J Cell Sci
Title: Unr defines a novel class of nucleoplasmic reticulum involved in mRNA translation.
Volume: 130
Issue: 10
Pages: 1796-1808
Publication  
First Author: Athanason MG
Year: 2016
Journal: Mol Cell Endocrinol
Title: Quantitative proteomic profiling reveals hepatic lipogenesis and liver X receptor activation in the PANDER transgenic model.
Volume: 436
Pages: 41-9
Publication
First Author: Alberti S
Year: 2000
Journal: Gene
Title: Structural characterisation of the mouse nuclear oxysterol receptor genes LXRalpha and LXRbeta.
Volume: 243
Issue: 1-2
Pages: 93-103
Publication
First Author: Korf H
Year: 2009
Journal: J Clin Invest
Title: Liver X receptors contribute to the protective immune response against Mycobacterium tuberculosis in mice.
Volume: 119
Issue: 6
Pages: 1626-37
Publication
First Author: Alberti S
Year: 2001
Journal: J Clin Invest
Title: Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRbeta-deficient mice.
Volume: 107
Issue: 5
Pages: 565-73
Publication
First Author: Steffensen KR
Year: 2003
Journal: Biochem Biophys Res Commun
Title: Gene expression profiling in adipose tissue indicates different transcriptional mechanisms of liver X receptors alpha and beta, respectively.
Volume: 310
Issue: 2
Pages: 589-93
Publication
First Author: Tobin KA
Year: 2002
Journal: J Biol Chem
Title: Liver X receptors as insulin-mediating factors in fatty acid and cholesterol biosynthesis.
Volume: 277
Issue: 12
Pages: 10691-7
Publication
First Author: Qin Y
Year: 2009
Journal: Biochim Biophys Acta
Title: Regulation of hepatic fatty acid elongase 5 by LXRalpha-SREBP-1c.
Volume: 1791
Issue: 2
Pages: 140-7
Publication
First Author: Dai YB
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Ablation of Liver X receptors α and β leads to spontaneous peripheral squamous cell lung cancer in mice.
Volume: 113
Issue: 27
Pages: 7614-9
Publication
First Author: Korach-André M
Year: 2011
Journal: Am J Physiol Endocrinol Metab
Title: Liver X receptors regulate de novo lipogenesis in a tissue-specific manner in C57BL/6 female mice.
Volume: 301
Issue: 1
Pages: E210-22
Publication
First Author: Kim HJ
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Stromal growth and epithelial cell proliferation in ventral prostates of liver X receptor knockout mice.
Volume: 106
Issue: 2
Pages: 558-63
Publication
First Author: Archer A
Year: 2014
Journal: Am J Physiol Endocrinol Metab
Title: Skeletal muscle as a target of LXR agonist after long-term treatment: focus on lipid homeostasis.
Volume: 306
Issue: 5
Pages: E494-502
Publication
First Author: Bogie JF
Year: 2012
Journal: PLoS One
Title: Myelin-derived lipids modulate macrophage activity by liver X receptor activation.
Volume: 7
Issue: 9
Pages: e44998
Publication
First Author: Korach-André M
Year: 2010
Journal: Am J Physiol Endocrinol Metab
Title: Separate and overlapping metabolic functions of LXRalpha and LXRbeta in C57Bl/6 female mice.
Volume: 298
Issue: 2
Pages: E167-78
Publication
First Author: Miao Y
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Liver X receptor β controls thyroid hormone feedback in the brain and regulates browning of subcutaneous white adipose tissue.
Volume: 112
Issue: 45
Pages: 14006-11
Publication
First Author: Andersson S
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Inactivation of liver X receptor beta leads to adult-onset motor neuron degeneration in male mice.
Volume: 102
Issue: 10
Pages: 3857-62
Publication
First Author: Dai YB
Year: 2016
Journal: Mol Psychiatry
Title: Liver X receptors regulate cerebrospinal fluid production.
Volume: 21
Issue: 6
Pages: 844-56
Publication
First Author: Wang L
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Liver X receptors in the central nervous system: from lipid homeostasis to neuronal degeneration.
Volume: 99
Issue: 21
Pages: 13878-83
Publication
First Author: Gerin I
Year: 2005
Journal: J Biol Chem
Title: LXRbeta is required for adipocyte growth, glucose homeostasis, and beta cell function.
Volume: 280
Issue: 24
Pages: 23024-31
Publication
First Author: Steffensen KR
Year: 2006
Journal: Mol Cell Endocrinol
Title: Reduced fertility and inability of oocytes to resume meiosis in mice deficient of the Lxr genes.
Volume: 256
Issue: 1-2
Pages: 9-16
Publication
First Author: Schuster GU
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Improved metabolic control by depletion of Liver X Receptors in mice.
Volume: 348
Issue: 1
Pages: 176-82
Publication
First Author: Steffensen KR
Year: 2004
Journal: J Mol Endocrinol
Title: Genome-wide expression profiling; a panel of mouse tissues discloses novel biological functions of liver X receptors in adrenals.
Volume: 33
Issue: 3
Pages: 609-22
Publication
First Author: Korach-André M
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Both liver-X receptor (LXR) isoforms control energy expenditure by regulating brown adipose tissue activity.
Volume: 108
Issue: 1
Pages: 403-8
Publication
First Author: Robertson KM
Year: 2005
Journal: Endocrinology
Title: The liver X receptor-{beta} is essential for maintaining cholesterol homeostasis in the testis.
Volume: 146
Issue: 6
Pages: 2519-30
Publication
First Author: Zitzer H
Year: 2006
Journal: Endocrinology
Title: Sterol regulatory element-binding protein 1 mediates liver X receptor-beta-induced increases in insulin secretion and insulin messenger ribonucleic acid levels.
Volume: 147
Issue: 8
Pages: 3898-905
Publication
First Author: Robertson KM
Year: 2006
Journal: J Bone Miner Res
Title: Cholesterol-sensing receptors, liver X receptor alpha and beta, have novel and distinct roles in osteoclast differentiation and activation.
Volume: 21
Issue: 8
Pages: 1276-87
Publication
First Author: Schuster GU
Year: 2002
Journal: Circulation
Title: Accumulation of foam cells in liver X receptor-deficient mice.
Volume: 106
Issue: 9
Pages: 1147-53
Publication
First Author: Gabbi C
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Estrogen-dependent gallbladder carcinogenesis in LXRbeta-/- female mice.
Volume: 107
Issue: 33
Pages: 14763-8
Publication
First Author: Zelcer N
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Attenuation of neuroinflammation and Alzheimer's disease pathology by liver x receptors.
Volume: 104
Issue: 25
Pages: 10601-6
Publication
First Author: Bousset L
Year: 2020
Journal: PLoS Biol
Title: Absence of nuclear receptors LXRs impairs immune response to androgen deprivation and leads to prostate neoplasia.
Volume: 18
Issue: 12
Pages: e3000948
Publication
First Author: Repa JJ
Year: 2000
Journal: Science
Title: Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers.
Volume: 289
Issue: 5484
Pages: 1524-9
Publication  
First Author: Ramón-Vázquez A
Year: 2019
Journal: Mol Cell Biol
Title: Common and Differential Transcriptional Actions of Nuclear Receptors Liver X Receptors α and β in Macrophages.
Volume: 39
Issue: 5
Publication
First Author: Pommier AJ
Year: 2013
Journal: PLoS Genet
Title: Liver x receptors protect from development of prostatic intra-epithelial neoplasia in mice.
Volume: 9
Issue: 5
Pages: e1003483
Publication
First Author: Patel R
Year: 2017
Journal: Endocrinology
Title: Separating the Anti-Inflammatory and Diabetogenic Effects of Glucocorticoids Through LXRβ Antagonism.
Volume: 158
Issue: 4
Pages: 1034-1047
Publication
First Author: Nikolova V
Year: 2017
Journal: Am J Physiol Endocrinol Metab
Title: Changes in LXR signaling influence early-pregnancy lipogenesis and protect against dysregulated fetoplacental lipid homeostasis.
Volume: 313
Issue: 4
Pages: E463-E472
Publication
First Author: Whitfield M
Year: 2016
Journal: Biol Reprod
Title: Liver X Receptors (LXRs) Alpha and Beta Play Distinct Roles in the Mouse Epididymis.
Volume: 94
Issue: 3
Pages: 55
Publication
First Author: Volle DH
Year: 2007
Journal: Mol Endocrinol
Title: Multiple roles of the nuclear receptors for oxysterols liver X receptor to maintain male fertility.
Volume: 21
Issue: 5
Pages: 1014-27
Publication
First Author: Ishikiriyama T
Year: 2021
Journal: PLoS One
Title: Contrasting functional responses of resident Kupffer cells and recruited liver macrophages to irradiation and liver X receptor stimulation.
Volume: 16
Issue: 7
Pages: e0254886
Publication
First Author: Cummins CL
Year: 2006
Journal: J Clin Invest
Title: Liver X receptors regulate adrenal cholesterol balance.
Volume: 116
Issue: 7
Pages: 1902-12
Publication
First Author: Lund EG
Year: 2006
Journal: Biochem Pharmacol
Title: Different roles of liver X receptor alpha and beta in lipid metabolism: effects of an alpha-selective and a dual agonist in mice deficient in each subtype.
Volume: 71
Issue: 4
Pages: 453-63
Publication
First Author: Ramírez CM
Year: 2013
Journal: Circ Res
Title: Control of cholesterol metabolism and plasma high-density lipoprotein levels by microRNA-144.
Volume: 112
Issue: 12
Pages: 1592-601
Publication
First Author: Mouzat K
Year: 2007
Journal: J Biol Chem
Title: Oxysterol nuclear receptor LXRbeta regulates cholesterol homeostasis and contractile function in mouse uterus.
Volume: 282
Issue: 7
Pages: 4693-701
Publication
First Author: Joseph SB
Year: 2003
Journal: Nat Med
Title: Reciprocal regulation of inflammation and lipid metabolism by liver X receptors.
Volume: 9
Issue: 2
Pages: 213-9
Publication
First Author: Hernández Vallejo SJ
Year: 2009
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Short-term adaptation of postprandial lipoprotein secretion and intestinal gene expression to a high-fat diet.
Volume: 296
Issue: 4
Pages: G782-92
Publication
First Author: Henry-Berger J
Year: 2008
Journal: Biol Reprod
Title: Endoglin (CD105) expression is regulated by the liver X receptor alpha (NR1H3) in human trophoblast cell line JAR.
Volume: 78
Issue: 6
Pages: 968-75
Publication
First Author: Zhao Z
Year: 2016
Journal: Am J Pathol
Title: Activation of Liver X Receptor Attenuates Oleic Acid-Induced Acute Respiratory Distress Syndrome.
Volume: 186
Issue: 10
Pages: 2614-22
Publication
First Author: Uppal H
Year: 2007
Journal: Hepatology
Title: Activation of LXRs prevents bile acid toxicity and cholestasis in female mice.
Volume: 45
Issue: 2
Pages: 422-32
Publication
First Author: Ducheix S
Year: 2017
Journal: PLoS One
Title: Dietary oleic acid regulates hepatic lipogenesis through a liver X receptor-dependent signaling.
Volume: 12
Issue: 7
Pages: e0181393
Publication
First Author: Patel R
Year: 2011
Journal: J Clin Invest
Title: LXRβ is required for glucocorticoid-induced hyperglycemia and hepatosteatosis in mice.
Volume: 121
Issue: 1
Pages: 431-41
Publication
First Author: Hichor M
Year: 2018
Journal: Sci Rep
Title: Liver X Receptor exerts a protective effect against the oxidative stress in the peripheral nerve.
Volume: 8
Issue: 1
Pages: 2524
Publication
First Author: Maqdasy S
Year: 2015
Journal: Endocrinology
Title: Identification of the Functions of Liver X Receptor-β in Sertoli Cells Using a Targeted Expression-Rescue Model.
Volume: 156
Issue: 12
Pages: 4545-57
Publication
First Author: Viennois E
Year: 2012
Journal: Endocrinology
Title: Lxrα regulates the androgen response in prostate epithelium.
Volume: 153
Issue: 7
Pages: 3211-23
Publication
First Author: Makoukji J
Year: 2011
Journal: J Neurosci
Title: Interplay between LXR and Wnt/β-catenin signaling in the negative regulation of peripheral myelin genes by oxysterols.
Volume: 31
Issue: 26
Pages: 9620-9
Publication
First Author: Dufour J
Year: 2013
Journal: PLoS One
Title: Lack of liver X receptors leads to cell proliferation in a model of mouse dorsal prostate epithelial cell.
Volume: 8
Issue: 3
Pages: e58876
Publication
First Author: Whitfield M
Year: 2017
Journal: Reproduction
Title: Dyslipidemia alters sperm maturation and capacitation in LXR-null mice.
Volume: 154
Issue: 6
Pages: 827-842
Publication
First Author: He C
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Macrophages release plasma membrane-derived particles rich in accessible cholesterol.
Volume: 115
Issue: 36
Pages: E8499-E8508
Publication
First Author: Oumeddour A
Year: 2014
Journal: Biochem Biophys Res Commun
Title: Liver X receptors interfere with the deleterious effect of diethylstilbestrol on testicular physiology.
Volume: 446
Issue: 3
Pages: 656-62
Publication
First Author: Patel M
Year: 2014
Journal: Diabetologia
Title: Liver X receptors preserve renal glomerular integrity under normoglycaemia and in diabetes in mice.
Volume: 57
Issue: 2
Pages: 435-46
Publication
First Author: Beaven SW
Year: 2013
Journal: Cell Metab
Title: Reciprocal regulation of hepatic and adipose lipogenesis by liver X receptors in obesity and insulin resistance.
Volume: 18
Issue: 1
Pages: 106-17
Publication
First Author: Joseph SB
Year: 2004
Journal: Cell
Title: LXR-dependent gene expression is important for macrophage survival and the innate immune response.
Volume: 119
Issue: 2
Pages: 299-309
Publication
First Author: Endo-Umeda K
Year: 2018
Journal: Sci Rep
Title: Liver X receptors regulate hepatic F4/80 + CD11b+ Kupffer cells/macrophages and innate immune responses in mice.
Volume: 8
Issue: 1
Pages: 9281
Publication
First Author: Ouvrier A
Year: 2011
Journal: PLoS One
Title: Dietary cholesterol-induced post-testicular infertility.
Volume: 6
Issue: 11
Pages: e26966
Publication
First Author: Kömüves LG
Year: 2002
Journal: J Invest Dermatol
Title: Oxysterol stimulation of epidermal differentiation is mediated by liver X receptor-beta in murine epidermis.
Volume: 118
Issue: 1
Pages: 25-34
Publication
First Author: Hessvik NP
Year: 2010
Journal: Am J Physiol Endocrinol Metab
Title: LXR{beta} is the dominant LXR subtype in skeletal muscle regulating lipogenesis and cholesterol efflux.
Volume: 298
Issue: 3
Pages: E602-13
Publication
First Author: Gong H
Year: 2009
Journal: J Biol Chem
Title: Activation of the liver X receptor prevents lipopolysaccharide-induced lung injury.
Volume: 284
Issue: 44
Pages: 30113-21
Publication
First Author: Wu S
Year: 2009
Journal: Cardiovasc Res
Title: Liver X receptors are negative regulators of cardiac hypertrophy via suppressing NF-kappaB signalling.
Volume: 84
Issue: 1
Pages: 119-26
Publication
First Author: Mouzat K
Year: 2009
Journal: Endocrinology
Title: Absence of nuclear receptors for oxysterols liver X receptor induces ovarian hyperstimulation syndrome in mice.
Volume: 150
Issue: 7
Pages: 3369-75
Publication
First Author: Laffitte BA
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes.
Volume: 98
Issue: 2
Pages: 507-12
Publication
First Author: Rigamonti E
Year: 2005
Journal: Circ Res
Title: Liver X receptor activation controls intracellular cholesterol trafficking and esterification in human macrophages.
Volume: 97
Issue: 7
Pages: 682-9
Publication
First Author: Edwards PA
Year: 2002
Journal: J Lipid Res
Title: BAREing it all: the adoption of LXR and FXR and their roles in lipid homeostasis.
Volume: 43
Issue: 1
Pages: 2-12
Publication
First Author: Annicotte JS
Year: 2004
Journal: Anat Rec A Discov Mol Cell Evol Biol
Title: Expression of the liver X receptor alpha and beta in embryonic and adult mice.
Volume: 277
Issue: 2
Pages: 312-6
Publication
First Author: Frenoux JM
Year: 2004
Journal: J Mol Endocrinol
Title: Nuclear oxysterol receptors, LXRs, are involved in the maintenance of mouse caput epididymidis structure and functions.
Volume: 33
Issue: 2
Pages: 361-75
Publication
First Author: Zelcer N
Year: 2006
Journal: J Clin Invest
Title: Liver X receptors as integrators of metabolic and inflammatory signaling.
Volume: 116
Issue: 3
Pages: 607-14
Publication
First Author: Lee JH
Year: 2008
Journal: Endocrinology
Title: Androgen deprivation by activating the liver X receptor.
Volume: 149
Issue: 8
Pages: 3778-88
Publication
First Author: Uno S
Year: 2009
Journal: Biochem Pharmacol
Title: Suppression of beta-catenin signaling by liver X receptor ligands.
Volume: 77
Issue: 2
Pages: 186-95
Publication
First Author: Soodvilai S
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: Liver X receptor agonists decrease ENaC-mediated sodium transport in collecting duct cells.
Volume: 303
Issue: 12
Pages: F1610-6
Publication
First Author: Hazra S
Year: 2012
Journal: Diabetes
Title: Liver X receptor modulates diabetic retinopathy outcome in a mouse model of streptozotocin-induced diabetes.
Volume: 61
Issue: 12
Pages: 3270-9
Publication
First Author: Meffre D
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Liver X receptors alpha and beta promote myelination and remyelination in the cerebellum.
Volume: 112
Issue: 24
Pages: 7587-92
Publication
First Author: Wang JZ
Year: 2017
Journal: Biochem Biophys Res Commun
Title: LXR agonists promote the proliferation of neural progenitor cells through MEK-ERK pathway.
Volume: 483
Issue: 1
Pages: 216-222
Publication
First Author: He Q
Year: 2014
Journal: Circ Heart Fail
Title: Activation of liver-X-receptor α but not liver-X-receptor β protects against myocardial ischemia/reperfusion injury.
Volume: 7
Issue: 6
Pages: 1032-41
Publication
First Author: Huang N
Year: 2015
Journal: Mol Oral Microbiol
Title: Liver X receptors contribute to periodontal pathogen-elicited inflammation and oral bone loss.
Volume: 30
Issue: 6
Pages: 438-50
Publication
First Author: Kotti TJ
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Brain cholesterol turnover required for geranylgeraniol production and learning in mice.
Volume: 103
Issue: 10
Pages: 3869-74
Publication
First Author: Gabbi C
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Pancreatic exocrine insufficiency in LXRbeta-/- mice is associated with a reduction in aquaporin-1 expression.
Volume: 105
Issue: 39
Pages: 15052-7
Publication
First Author: Kim HJ
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Liver X receptor beta (LXRbeta): a link between beta-sitosterol and amyotrophic lateral sclerosis-Parkinson's dementia.
Volume: 105
Issue: 6
Pages: 2094-9
Publication
First Author: Mori H
Year: 2012
Journal: J Clin Invest
Title: Secreted frizzled-related protein 5 suppresses adipocyte mitochondrial metabolism through WNT inhibition.
Volume: 122
Issue: 7
Pages: 2405-16
Publication
First Author: Archer A
Year: 2012
Journal: Mol Endocrinol
Title: Fasting-induced FGF21 is repressed by LXR activation via recruitment of an HDAC3 corepressor complex in mice.
Volume: 26
Issue: 12
Pages: 1980-90
Publication
First Author: Gabbi C
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Central diabetes insipidus associated with impaired renal aquaporin-1 expression in mice lacking liver X receptor β.
Volume: 109
Issue: 8
Pages: 3030-4