Type |
Details |
Score |
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Allele |
Name: |
transferrin; hypotransferrinemia with hemochromatosis |
Allele Type: |
Spontaneous |
|
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Altruda F |
Year: |
1988 |
Journal: |
J Mol Evol |
Title: |
Structure of the human hemopexin gene and evidence for intron-mediated evolution. |
Volume: |
27 |
Issue: |
2 |
Pages: |
102-8 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Hemopexin (HPX) is the plasma protein with the highest binding affinity to haem among known proteins []. It binds haem and transports it to the liver for breakdown and iron recovery, after which the free HPX returns to the circulation []. It has been suggested that HPX is mainly responsible for the transportation of haem thus preventing both haem-catalysed oxidative damage and haem-bound iron loss []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Bernstein SE |
Year: |
1987 |
Journal: |
J Lab Clin Med |
Title: |
Hereditary hypotransferrinemia with hemosiderosis, a murine disorder resembling human atransferrinemia. |
Volume: |
110 |
Issue: |
6 |
Pages: |
690-705 |
|
•
•
•
•
•
|
Publication |
First Author: |
Larsen R |
Year: |
2010 |
Journal: |
Sci Transl Med |
Title: |
A central role for free heme in the pathogenesis of severe sepsis. |
Volume: |
2 |
Issue: |
51 |
Pages: |
51ra71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Levy JE |
Year: |
1999 |
Journal: |
Nat Genet |
Title: |
Transferrin receptor is necessary for development of erythrocytes and the nervous system. |
Volume: |
21 |
Issue: |
4 |
Pages: |
396-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yalamanoglu A |
Year: |
2018 |
Journal: |
Am J Physiol Lung Cell Mol Physiol |
Title: |
Depletion of haptoglobin and hemopexin promote hemoglobin-mediated lipoprotein oxidation in sickle cell disease. |
Volume: |
315 |
Issue: |
5 |
Pages: |
L765-L774 |
|
•
•
•
•
•
|
Publication |
First Author: |
Buehler PW |
Year: |
2021 |
Journal: |
Free Radic Biol Med |
Title: |
Hemopexin dosing improves cardiopulmonary dysfunction in murine sickle cell disease. |
Volume: |
175 |
|
Pages: |
95-107 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dickinson TK |
Year: |
1998 |
Journal: |
Brain Res |
Title: |
Immunohistochemical analysis of transferrin receptor: regional and cellular distribution in the hypotransferrinemic (hpx) mouse brain. |
Volume: |
801 |
Issue: |
1-2 |
Pages: |
171-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Trenor CC 3rd |
Year: |
2000 |
Journal: |
Blood |
Title: |
The molecular defect in hypotransferrinemic mice. |
Volume: |
96 |
Issue: |
3 |
Pages: |
1113-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bartnikas TB |
Year: |
2011 |
Journal: |
Blood |
Title: |
Transferrin is a major determinant of hepcidin expression in hypotransferrinemic mice. |
Volume: |
117 |
Issue: |
2 |
Pages: |
630-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ohta M |
Year: |
2018 |
Journal: |
Transgenic Res |
Title: |
Co-precipitation molecules hemopexin and transferrin may be key molecules for fibrillogenesis in TTR V30M amyloidogenesis. |
Volume: |
27 |
Issue: |
1 |
Pages: |
15-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lederman M |
Year: |
2012 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Retinal function and structure in the hypotransferrinemic mouse. |
Volume: |
53 |
Issue: |
2 |
Pages: |
605-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ariyoshi N |
Year: |
1998 |
Journal: |
J Biol Chem |
Title: |
Characterization of the rat Star gene that encodes the predominant 3.5-kilobase pair mRNA. ACTH stimulation of adrenal steroids in vivo precedes elevation of Star mRNA and protein. |
Volume: |
273 |
Issue: |
13 |
Pages: |
7610-9 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
460
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Tolosano E |
Year: |
2002 |
Journal: |
DNA Cell Biol |
Title: |
Hemopexin: structure, function, and regulation. |
Volume: |
21 |
Issue: |
4 |
Pages: |
297-306 |
|
•
•
•
•
•
|