|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1501 to 1600 out of 1650 for Prnp

<< First    < Previous  |  Next >    Last >>
0.041s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Strain
MGI:5563241 | STOCK Prnp<tm1Cwe> Tg(Prnp)E1Rchi/Cnrm
Attribute String: mutant stock, targeted mutation, transgenic
•
•
•
•
•
Strain
MGI:7571104 | B6.Cg-Prnp<tm1Cwe> Tg(Prnp)E1Rchi/Cnrm
Attribute String: congenic, mutant strain, targeted mutation, transgenic
•
•
•
•
•
Genotype
Genotype
Symbol: Prnp/Prnp Tg(Prnp)a19Cwe/?
Background: Not Specified
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Prnp/Prnp Tg(Prnp)a20Cwe/?
Background: Not Specified
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Prkce/Prkce Tg(Prnp-tTA)F959Sbp/? Tg(tetO-Prkce)T9Msg/?
Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J * FVB/N
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Prnp/Prnp Tg(Nefh-cre)22Jcol/? Tg(Prnp)37Jcol/?
Background: involves: 129/Sv * 129S7/SvEvBrd * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(Prnp-ITM2B*)6Jckr/? Tg(Thy1-APP)3Somm/?
Background: B6.Cg-Tg(Prnp-ITM2B*)6Jckr Tg(Thy1-APP)3Somm
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Prnp/Prnp Tg(Prnp)a20Cwe/?
Background: involves: 129S7/SvEvBrd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(Prnp-tTA)F959Sbp/? Tg(TetO-Nfkbia*S32A*S36A)1Wcg/?
Background: involves: 129S7/SvEvBrd * DBA * FVB/N
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(Prnp*P101L)174Sbp/?
Background: involves: C57BL/6 * SJL
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(Prnp-ITM2B*)1Ruvi/Tg(Prnp-ITM2B*)1Ruvi Tg(Prnp-MAPT*P301L)#Ruvi/Tg(Prnp-MAPT*P301L)#Ruvi
Background: involves: C3HeB/FeJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Prnp/Prnp Tg(Prnp*S170N*N174T)1020Aag/?
Background: involves: 129S7/SvEvBrd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Publication
14704188 | J:89558
First Author: Moreno CR
Year: 2003
Journal: Genetics
Title: Detection of new quantitative trait Loci for susceptibility to transmissible spongiform encephalopathies in mice.
Volume: 165
Issue: 4
Pages: 2085-91
•
•
•
•
•
Publication
32683652 | J:312810
First Author: Lidón L
Year: 2020
Journal: Mol Neurobiol
Title: Tau Protein as a New Regulator of Cellular Prion Protein Transcription.
Volume: 57
Issue: 10
Pages: 4170-4186
•
•
•
•
•
Publication
23817016 | J:207052
 
First Author: Ansoleaga B
Year: 2013
Journal: Neuroscience
Title: Dysregulation of brain olfactory and taste receptors in AD, PSP and CJD, and AD-related model.
Volume: 248
Pages: 369-82
•
•
•
•
•
Publication
21757544 | J:183031
First Author: Carulla P
Year: 2011
Journal: Mol Biol Cell
Title: Neuroprotective role of PrPC against kainate-induced epileptic seizures and cell death depends on the modulation of JNK3 activation by GluR6/7-PSD-95 binding.
Volume: 22
Issue: 17
Pages: 3041-54
•
•
•
•
•
Publication
24278249 | J:342189
First Author: Naughton BJ
Year: 2013
Journal: PLoS One
Title: Amyloidosis, synucleinopathy, and prion encephalopathy in a neuropathic lysosomal storage disease: the CNS-biomarker potential of peripheral blood.
Volume: 8
Issue: 11
Pages: e80142
•
•
•
•
•
Publication
11734625 | J:73484
First Author: Moore RC
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Doppel-induced cerebellar degeneration in transgenic mice.
Volume: 98
Issue: 26
Pages: 15288-93
•
•
•
•
•
Publication
9934678 | J:52942
 
First Author: Windl O
Year: 1999
Journal: J Gen Virol
Title: Construction and characterization of murine neuroblastoma cell clones allowing inducible and high expression of the prion protein.
Volume: 80 ( Pt 1)
Pages: 15-21
•
•
•
•
•
Publication
15007176 | J:88914
First Author: Anderson L
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Transgene-driven expression of the Doppel protein in Purkinje cells causes Purkinje cell degeneration and motor impairment.
Volume: 101
Issue: 10
Pages: 3644-9
•
•
•
•
•
Publication
16809423 | J:111815
First Author: Asante EA
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Dissociation of pathological and molecular phenotype of variant Creutzfeldt-Jakob disease in transgenic human prion protein 129 heterozygous mice.
Volume: 103
Issue: 28
Pages: 10759-64
•
•
•
•
•
Publication
21084466 | J:168804
First Author: Plinston C
Year: 2011
Journal: J Virol
Title: Increased susceptibility of human-PrP transgenic mice to bovine spongiform encephalopathy infection following passage in sheep.
Volume: 85
Issue: 3
Pages: 1174-81
•
•
•
•
•
Publication
26061765 | J:224080
First Author: Asante EA
Year: 2015
Journal: Nature
Title: A naturally occurring variant of the human prion protein completely prevents prion disease.
Volume: 522
Issue: 7557
Pages: 478-81
•
•
•
•
•
Publication
29579157 | J:264532
First Author: Ding NZ
Year: 2018
Journal: Biol Reprod
Title: Cellular prion protein is involved in decidualization of mouse uterus.
Volume: 99
Issue: 2
Pages: 319-325
•
•
•
•
•
Publication
32516343 | J:290651
First Author: Asante EA
Year: 2020
Journal: PLoS Biol
Title: Spontaneous generation of prions and transmissible PrP amyloid in a humanised transgenic mouse model of A117V GSS.
Volume: 18
Issue: 6
Pages: e3000725
•
•
•
•
•
Publication
32606072 | J:304259
 
First Author: Avar M
Year: 2020
Journal: Life Sci Alliance
Title: Prion infection, transmission, and cytopathology modeled in a low-biohazard human cell line.
Volume: 3
Issue: 8
•
•
•
•
•
Publication
33851575 | J:304714
   
First Author: Bistaffa E
Year: 2021
Journal: Elife
Title: PMCA-generated prions from the olfactory mucosa of patients with Fatal Familial Insomnia cause prion disease in mice.
Volume: 10
•
•
•
•
•
Publication
37798679 | J:342503
First Author: Schweighauser M
Year: 2023
Journal: Acta Neuropathol Commun
Title: Cryo-EM structures of tau filaments from the brains of mice transgenic for human mutant P301S Tau.
Volume: 11
Issue: 1
Pages: 160
•
•
•
•
•
Allele
Tg(Prnp/PRNP*AHQ)EM52Pcg | MGI:5776255
Name: transgene insertion EM52, Peter Griffiths
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
•
•
•
•
•
Publication
31878336 | J:346775
 
First Author: Leparulo A
Year: 2019
Journal: Cells
Title: Dampened Slow Oscillation Connectivity Anticipates Amyloid Deposition in the PS2APP Mouse Model of Alzheimer's Disease.
Volume: 9
Issue: 1
•
•
•
•
•
Publication
27889678 | J:239743
 
First Author: Fontana R
Year: 2017
Journal: Neurobiol Aging
Title: Early hippocampal hyperexcitability in PS2APP mice: role of mutant PS2 and APP.
Volume: 50
Pages: 64-76
•
•
•
•
•
Publication
22464332 | J:186082
First Author: Nakamura K
Year: 2012
Journal: Cell
Title: Proline isomer-specific antibodies reveal the early pathogenic tau conformation in Alzheimer's disease.
Volume: 149
Issue: 1
Pages: 232-44
•
•
•
•
•
Allele
Tg(Prnp/PRNP*AHQ)EM16Pcg | MGI:5776247
Name: transgene insertion EM16, Peter Griffiths
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
•
•
•
•
•
Publication
18322092 | J:132774
First Author: Nuber S
Year: 2008
Journal: J Neurosci
Title: Neurodegeneration and motor dysfunction in a conditional model of Parkinson's disease.
Volume: 28
Issue: 10
Pages: 2471-84
•
•
•
•
•
Publication
21093594 | J:204506
First Author: Odeh F
Year: 2011
Journal: Neuroimage
Title: Atlas of transgenic Tet-Off Ca2+/calmodulin-dependent protein kinase II and prion protein promoter activity in the mouse brain.
Volume: 54
Issue: 4
Pages: 2603-11
•
•
•
•
•
Publication
25946042 | J:235351
First Author: Liu P
Year: 2015
Journal: PLoS One
Title: Characterization of a Novel Mouse Model of Alzheimer's Disease--Amyloid Pathology and Unique β-Amyloid Oligomer Profile.
Volume: 10
Issue: 5
Pages: e0126317
•
•
•
•
•
Publication
34157306 | J:330683
First Author: Shi Y
Year: 2021
Journal: Neuron
Title: Overexpressing low-density lipoprotein receptor reduces tau-associated neurodegeneration in relation to apoE-linked mechanisms.
Volume: 109
Issue: 15
Pages: 2413-2426.e7
•
•
•
•
•
Strain
MGI:5779529 | STOCK Prnp<tm1Cwe> Tg(Prnp/PRNP*ARR)FM16Pcg/H
Attribute String: transgenic, targeted mutation, mutant stock
•
•
•
•
•
Strain
MGI:4452508 | C57BL/6-Tg(Prnp-ITM2B*)7Jckr Tg(Thy1-APPSw,Thy1-PSEN1*L166P)21Jckr
Attribute String: transgenic, mutant strain, coisogenic
•
•
•
•
•
Strain
MGI:4452515 | B6.Cg-Tg(Prnp-ITM2B*)7Jckr Tg(Thy1-MAPT*P301S)2541Godt
Attribute String: transgenic, mutant strain, congenic
•
•
•
•
•
Strain
MGI:3807390 | B6.Cg-Tg(Prnp-ITM2B/APP695*42)A12Emcg/J
Attribute String: transgenic, congenic
•
•
•
•
•
Strain
MGI:3711081 | B6;C3-Tg(Prnp-ITM2B/APP695*42)A12Emcg/Mmjax
Attribute String: transgenic, mutant stock
•
•
•
•
•
Publication
33161213 | J:305383
 
First Author: Hendrix RD
Year: 2021
Journal: Neurobiol Aging
Title: Alzheimer amyloid-β- peptide disrupts membrane localization of glucose transporter 1 in astrocytes: implications for glucose levels in brain and blood.
Volume: 97
Pages: 73-88
•
•
•
•
•
Publication
19924302 | J:155411
First Author: Giliberto L
Year: 2009
Journal: PLoS One
Title: Generation and initial characterization of FDD knock in mice.
Volume: 4
Issue: 11
Pages: e7900
•
•
•
•
•
Allele
Tg(Prnp)940Zbz | MGI:5318492
Name: transgene insertion 940, University Hospital Zurich
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
•
•
•
•
•
Strain
MGI:4821476 | B6.Cg-Prnp<tm2Edin> Tg(Prnp)a20Cwe
Attribute String: congenic, mutant strain, targeted mutation, transgenic
•
•
•
•
•
Publication
27185853 | J:234780
First Author: Zhu C
Year: 2016
Journal: J Exp Med
Title: A neuroprotective role for microglia in prion diseases.
Volume: 213
Issue: 6
Pages: 1047-59
•
•
•
•
•
Publication
22504650 | J:188671
First Author: Mok SW
Year: 2012
Journal: J Immunol
Title: B cell-specific S1PR1 deficiency blocks prion dissemination between secondary lymphoid organs.
Volume: 188
Issue: 10
Pages: 5032-40
•
•
•
•
•
Publication
22396390 | J:217143
First Author: Labbadia J
Year: 2012
Journal: Brain
Title: Suppression of protein aggregation by chaperone modification of high molecular weight complexes.
Volume: 135
Issue: Pt 4
Pages: 1180-96
•
•
•
•
•
Strain
MGI:4452514 | B6.Cg-Tg(Prnp-ITM2B*)6Jckr Tg(Thy1-MAPT*P301S)2541Godt
Attribute String: congenic, mutant strain, transgenic
•
•
•
•
•
Allele
Tg(Prnp/PRNP*AHQ)EF50Pcg | MGI:5776258
Name: transgene insertion EM50, Peter Griffiths
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
•
•
•
•
•
Publication
25607368 | J:219567
First Author: Peretti D
Year: 2015
Journal: Nature
Title: RBM3 mediates structural plasticity and protective effects of cooling in neurodegeneration.
Volume: 518
Issue: 7538
Pages: 236-9
•
•
•
•
•
Publication
12761044 | J:83809
First Author: Gilbert R
Year: 2003
Journal: Hum Mol Genet
Title: Prolonged dystrophin expression and functional correction of mdx mouse muscle following gene transfer with a helper-dependent (gutted) adenovirus-encoding murine dystrophin.
Volume: 12
Issue: 11
Pages: 1287-99
•
•
•
•
•
Allele
Tg(Prnp)941Zbz | MGI:5318499
Name: transgene insertion 941, University Hospital Zurich
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
•
•
•
•
•
Publication
31980586 | J:285719
First Author: Meilandt WJ
Year: 2020
Journal: J Neurosci
Title: Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aβ42:Aβ40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mouse Model.
Volume: 40
Issue: 9
Pages: 1956-1974
•
•
•
•
•
Strain
MGI:5614761 | STOCK Prnp<tm1Cwe> Tg(Prnp*D177N*M128V)G1Rchi/Cnrm
Attribute String: mutant stock, targeted mutation, transgenic
•
•
•
•
•
Publication
34965428 | J:321071
First Author: Lee SH
Year: 2021
Journal: Cell Rep
Title: TREM2-independent oligodendrocyte, astrocyte, and T cell responses to tau and amyloid pathology in mouse models of Alzheimer disease.
Volume: 37
Issue: 13
Pages: 110158
•
•
•
•
•
Publication
33675684 | J:304468
First Author: Lee SH
Year: 2021
Journal: Neuron
Title: Trem2 restrains the enhancement of tau accumulation and neurodegeneration by β-amyloid pathology.
Volume: 109
Issue: 8
Pages: 1283-1301.e6
•
•
•
•
•
Strain
MGI:5762587 | STOCK Prnp<tm1Cwe> Tg(Prnp/PRNP)1Drb/H
Attribute String: mutant stock, targeted mutation, transgenic
•
•
•
•
•
Publication
30333186 | J:267076
First Author: Sharkey LM
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Mutant UBQLN2 promotes toxicity by modulating intrinsic self-assembly.
Volume: 115
Issue: 44
Pages: E10495-E10504
•
•
•
•
•
Publication
36609661 | J:334796
First Author: Sandoval-Pistorius SS
Year: 2023
Journal: Sci Rep
Title: Ubiquilin-2 regulates pathological alpha-synuclein.
Volume: 13
Issue: 1
Pages: 293
•
•
•
•
•
Strain
MGI:5614055 | B6.Cg-Tg(Thy1-APPSwe,Prnp-PSEN2*N141I)152HLaoz Tg(Thy1-MAPT)183Gotz
Attribute String: transgenic, mutant strain, congenic
•
•
•
•
•
Publication
19781645 | J:154968
First Author: Grueninger F
Year: 2010
Journal: Neurobiol Dis
Title: Phosphorylation of Tau at S422 is enhanced by Abeta in TauPS2APP triple transgenic mice.
Volume: 37
Issue: 2
Pages: 294-306
•
•
•
•
•
Publication
19897719 | J:154750
First Author: Rhein V
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Amyloid-beta and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice.
Volume: 106
Issue: 47
Pages: 20057-62
•
•
•
•
•
Publication
30089252 | J:270688
First Author: Restelli LM
Year: 2018
Journal: Cell Rep
Title: Neuronal Mitochondrial Dysfunction Activates the Integrated Stress Response to Induce Fibroblast Growth Factor 21.
Volume: 24
Issue: 6
Pages: 1407-1414
•
•
•
•
•
Publication
18431510 | J:135144
First Author: Lim J
Year: 2008
Journal: J Clin Invest
Title: Pin1 has opposite effects on wild-type and P301L tau stability and tauopathy.
Volume: 118
Issue: 5
Pages: 1877-89
•
•
•
•
•
Publication
19402954 | J:337203
First Author: Angers RC
Year: 2009
Journal: Emerg Infect Dis
Title: Chronic wasting disease prions in elk antler velvet.
Volume: 15
Issue: 5
Pages: 696-703
•
•
•
•
•
Strain
MGI:4834336 | B6.129P2-Prnp/Prnd<tm1Aag>/Cnrm
Attribute String: congenic, mutant strain, targeted mutation
•
•
•
•
•
Strain
MGI:5014497 | STOCK Prnp<tm1Cwe> Tg(Pcp2-Prnp)E330Zbz/Cnrm
Attribute String: mutant stock, targeted mutation, transgenic
•
•
•
•
•
Publication
10595524 | J:61052
First Author: Ishihara T
Year: 1999
Journal: Neuron
Title: Age-dependent emergence and progression of a tauopathy in transgenic mice overexpressing the shortest human tau isoform.
Volume: 24
Issue: 3
Pages: 751-62
•
•
•
•
•
Publication
15203189 | J:90946
First Author: Nakashima H
Year: 2004
Journal: Free Radic Biol Med
Title: Effects of alpha-tocopherol on an animal model of tauopathies.
Volume: 37
Issue: 2
Pages: 176-86
•
•
•
•
•
Publication
31492812 | J:279460
First Author: Kanata E
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: RNA editing alterations define manifestation of prion diseases.
Volume: 116
Issue: 39
Pages: 19727-19735
•
•
•
•
•
Strain
MGI:5775418 | STOCK Prnp<tm1Cwe> Tg(Prnp-PRNP*6OR)K6M16Pcg/H
Attribute String: mutant stock, transgenic
•
•
•
•
•
Strain
MGI:3711080 | B6;C3-Tg(Prnp-ITM2B/APP695*40)1Emcg/J
Attribute String: mutant stock, targeted mutation
•
•
•
•
•
Strain
MGI:3796980 | B6.Cg-Tg(Prnp-ITM2B/APP695*40)1Emcg/J
Attribute String: congenic, transgenic
•
•
•
•
•
Strain
MGI:5561198 | STOCK Prnp<tm1Cwe> Tg(Prnp*)CDah/Cnrm
Attribute String: targeted mutation, mutant stock, transgenic
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(Prnp-ITM2B/APP695*40)1Emcg/?
Background: involves: C3H * C57BL/6
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(Prnp-ITM2B/APP695*42)A12Emcg/?
Background: involves: C3H * C57BL/6
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Prnp/Prnp Tg(Nefh-cre)22Jcol/? Tg(Prnp)46Jcol/?
Background: involves: 129/Sv * 129S7/SvEvBrd * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Prnp/Prnp Tg(Nefh-cre)22Jcol/Tg(Nefh-cre)22Jcol Tg(Prnp)46Jcol/Tg(Prnp)46Jcol
Background: involves: 129/Sv * 129S7/SvEvBrd * C57BL/6 * FVB
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Apoe/Apoe Tg(Prnp-Abca1)EHol/?
Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(APPV717F)109Ili/? Tg(Prnp-Abca1)EHol/?
Background: involves: C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Prnp/Prnp Tg(Prnp-tTA)F959Sbp/? Tg(tetO-ATXN3)2904Olri/?
Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Prnp/Prnp Tg(Prnp-tTA)F959Sbp/Tg(Prnp-tTA)F959Sbp Tg(tetO-ATXN3)2904Olri/?
Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Prnp/Prnp Tg(Prnp-tTA)F959Sbp/? Tg(tetO-ATXN3)2904Olri/Tg(tetO-ATXN3)2904Olri
Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Prnp/Prnp Tg(Prnp-tTA)F959Sbp/Tg(Prnp-tTA)F959Sbp Tg(tetO-ATXN3)2904Olri/Tg(tetO-ATXN3)2904Olri
Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(Thy1-APPSwe,Prnp-PSEN2*N141I)152HLaoz/? Tg(Thy1-MAPT)183Gotz/?
Background: B6.Cg-Tg(Thy1-APPSwe,Prnp-PSEN2*N141I)152HLaoz Tg(Thy1-MAPT)183Gotz
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(Prnp-ITM2B*)7Jckr/? Tg(Thy1-MAPT*P301S)2541Godt/?
Background: B6.Cg-Tg(Prnp-ITM2B*)7Jckr Tg(Thy1-MAPT*P301S)2541Godt
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(Prnp-ITM2B*)7Jckr/? Tg(Thy1-APPSw,Thy1-PSEN1*L166P)21Jckr/?
Background: C57BL/6-Tg(Prnp-ITM2B*)7Jckr Tg(Thy1-APPSw,Thy1-PSEN1*L166P)21Jckr
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Prnp/Prnp Tg(Prnp)C4Cwe/?
Background: involves: 129S7/SvEvBrd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Prnp/Prnp Tg(Prnp)a20Cwe/?
Background: B6.Cg-Prnp Tg(Prnp)a20Cwe
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(Camk2a-tTA)1Mmay/? Tg(tetO/Prnp-APP*Swe*Lon)9191Krz/?
Background: involves: 129S6/SvEvTac * FVB/N
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Publication
20206252 | J:160641
First Author: Harrison PM
Year: 2010
Journal: Genomics
Title: Genomic assessment of the evolution of the prion protein gene family in vertebrates.
Volume: 95
Issue: 5
Pages: 268-77
•
•
•
•
•
Publication
31551718 | J:284428
 
First Author: Bradford BM
Year: 2019
Journal: Front Cell Neurosci
Title: Discrimination of Prion Strain Targeting in the Central Nervous System via Reactive Astrocyte Heterogeneity in CD44 Expression.
Volume: 13
Pages: 411
•
•
•
•
•
Publication
26423950 | J:325507
First Author: Duque Velásquez C
Year: 2015
Journal: J Virol
Title: Deer Prion Proteins Modulate the Emergence and Adaptation of Chronic Wasting Disease Strains.
Volume: 89
Issue: 24
Pages: 12362-73
•
•
•
•
•
Strain
MGI:5776256 | FVB(129S7)-Tg(Prnp/PRNP*AHQ)EM52Pcg/H
Attribute String: transgenic, coisogenic, mutant strain
•
•
•
•
•
Publication
27482889 | J:237253
First Author: Pedigo CE
Year: 2016
Journal: J Clin Invest
Title: Local TNF causes NFATc1-dependent cholesterol-mediated podocyte injury.
Volume: 126
Issue: 9
Pages: 3336-50
•
•
•
•
•
Publication
34644146 | J:324411
First Author: Xiang X
Year: 2021
Journal: Sci Transl Med
Title: Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases.
Volume: 13
Issue: 615
Pages: eabe5640
•
•
•
•
•
Publication
20005821 | J:155809
First Author: Kim J
Year: 2009
Journal: Neuron
Title: Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular A beta clearance.
Volume: 64
Issue: 5
Pages: 632-44
•
•
•
•
•
Strain
MGI:5776253 | FVB(129S7)-Tg(Prnp/PRNP*AHQ)EM16Pcg/H
Attribute String: mutant strain, transgenic
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom