Type |
Details |
Score |
Publication |
First Author: |
Zhang W |
Year: |
2007 |
Journal: |
Zhonghua Yi Xue Za Zhi |
Title: |
[Effect of hypertonic medium on expression of aquaporin-1 in pleural mesothelial cells: experiment with rats]. |
Volume: |
87 |
Issue: |
35 |
Pages: |
2508-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang Y |
Year: |
2008 |
Journal: |
Zhongguo Wei Zhong Bing Ji Jiu Yi Xue |
Title: |
[Expression of renal aquaporin 2 after circulatory arrest]. |
Volume: |
20 |
Issue: |
4 |
Pages: |
210-3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hwang IK |
Year: |
2007 |
Journal: |
J Neurosci Res |
Title: |
Aquaporin 9 changes in pyramidal cells before and is expressed in astrocytes after delayed neuronal death in the ischemic hippocampal CA1 region of the gerbil. |
Volume: |
85 |
Issue: |
11 |
Pages: |
2470-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hyndman KA |
Year: |
2016 |
Journal: |
Am J Physiol Regul Integr Comp Physiol |
Title: |
Dynamin-2 is a novel NOS1β interacting protein and negative regulator in the collecting duct. |
Volume: |
310 |
Issue: |
7 |
Pages: |
R570-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hyndman KA |
Year: |
2013 |
Journal: |
Hypertension |
Title: |
Renal collecting duct NOS1 maintains fluid-electrolyte homeostasis and blood pressure. |
Volume: |
62 |
Issue: |
1 |
Pages: |
91-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kittikulsuth W |
Year: |
2014 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Lack of an effect of collecting duct-specific deletion of adenylyl cyclase 3 on renal Na+ and water excretion or arterial pressure. |
Volume: |
306 |
Issue: |
6 |
Pages: |
F597-607 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang D |
Year: |
2020 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Loss of circadian gene Bmal1 in the collecting duct lowers blood pressure in male, but not female, mice. |
Volume: |
318 |
Issue: |
3 |
Pages: |
F710-F719 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ge Y |
Year: |
2006 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Collecting duct-specific knockout of the endothelin B receptor causes hypertension and sodium retention. |
Volume: |
291 |
Issue: |
6 |
Pages: |
F1274-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pavlov TS |
Year: |
2013 |
Journal: |
FASEB J |
Title: |
Regulation of ENaC in mice lacking renal insulin receptors in the collecting duct. |
Volume: |
27 |
Issue: |
7 |
Pages: |
2723-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schneider MP |
Year: |
2008 |
Journal: |
Hypertension |
Title: |
Collecting duct-derived endothelin regulates arterial pressure and Na excretion via nitric oxide. |
Volume: |
51 |
Issue: |
6 |
Pages: |
1605-10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ahn D |
Year: |
2004 |
Journal: |
J Clin Invest |
Title: |
Collecting duct-specific knockout of endothelin-1 causes hypertension and sodium retention. |
Volume: |
114 |
Issue: |
4 |
Pages: |
504-11 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Adcy3/Adcy3 Adcy6/Adcy6 Tg(AQP2-cre)2Dek/? |
Background: |
involves: 129X1/SvJ * C57BL/6 * CBA |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Aqp2/Aqp2<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> |
Background: |
involves: 129S6/SvEvTac * C57BL/6N |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Itoh T |
Year: |
2005 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Identification of a novel aquaporin, AQP12, expressed in pancreatic acinar cells. |
Volume: |
330 |
Issue: |
3 |
Pages: |
832-8 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
The aquaporins (AQPs) are a family of integral membrane proteins composed of two subfamilies: the orthodox aquaporins, which transport only water, and the aquaglyceroporins, which transport glycerol, urea, or other small solutes []. AQP1 in pleural mesothelial cells participate in the formation of pleural fluid [], renal AQP2 is involved in levels of solutes []and changes in AQP9 in the hippocampus are related to delayed neuronal death []. Aquaporins contain two tandem repeats, each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).Aquaporins 11 and 12 are classified as members of a new AQP subfamily: the subcellular AQPs []. AQP 11 and 12 appear to be more distantly related to the other mammalian aquaporins and aquaglyceroporins. AQP11 is functionally distinct from other proteins of the aquaporin superfamily and could represent a new aquaporin subfamily []. In members of the subcellular AQPs, one of the two asparagine-proline-alanine (NPA) motifs are not completely conserved. They play a crucial role in selective water conduction and function as water channels []. This group represents an aquaporin types 11 and 12. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
The aquaporins (AQPs) are a family of integral membrane proteins composed of two subfamilies: the orthodox aquaporins, which transport only water, and the aquaglyceroporins, which transport glycerol, urea, or other small solutes []. AQP1 in pleural mesothelial cells participate in the formation of pleural fluid [], renal AQP2 is involved in levels of solutes []and changes in AQP9 in the hippocampus are related to delayed neuronal death []. Aquaporins contain two tandem repeats, each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).Aquaporin-11 and aquaporin-12 (AQP12) belong to a new aquaporin subfamily termed superaquaporins []. AQP12 is exclusively found in pancreatic acinar cells [], and is not localised in the plasma membrane. No specific localisation has yet been established for this subfamily, but its presence in the pancreas implies some role in the secretion of digestive enzymes []and fluids in the pancreatic cells []. A structural characteristic of AQP12 is the lack of a cytoplasmic N-terminal region, by contrast with all other known aquaporins. |
|
•
•
•
•
•
|
Publication |
First Author: |
He W |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
Generation of a tenascin-C-CreER2 knockin mouse line for conditional DNA recombination in renal medullary interstitial cells. |
Volume: |
8 |
Issue: |
11 |
Pages: |
e79839 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang X |
Year: |
2009 |
Journal: |
Development |
Title: |
beta1 integrin is necessary for ureteric bud branching morphogenesis and maintenance of collecting duct structural integrity. |
Volume: |
136 |
Issue: |
19 |
Pages: |
3357-66 |
|
•
•
•
•
•
|
Publication |
First Author: |
Christensen BM |
Year: |
2010 |
Journal: |
J Am Soc Nephrol |
Title: |
Sodium and potassium balance depends on αENaC expression in connecting tubule. |
Volume: |
21 |
Issue: |
11 |
Pages: |
1942-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ge Y |
Year: |
2007 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Role of prostaglandins in collecting duct-derived endothelin-1 regulation of blood pressure and water excretion. |
Volume: |
293 |
Issue: |
6 |
Pages: |
F1805-10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Raphael KL |
Year: |
2009 |
Journal: |
Kidney Int |
Title: |
Inactivation of Pkd1 in principal cells causes a more severe cystic kidney disease than in intercalated cells. |
Volume: |
75 |
Issue: |
6 |
Pages: |
626-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li L |
Year: |
2013 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Reduced ENaC activity and blood pressure in mice with genetic knockout of the insulin receptor in the renal collecting duct. |
Volume: |
304 |
Issue: |
3 |
Pages: |
F279-88 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hofmeister MV |
Year: |
2011 |
Journal: |
Adv Exp Med Biol |
Title: |
The TRPV5 promoter as a tool for generation of transgenic mouse models. |
Volume: |
704 |
|
Pages: |
277-86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen D |
Year: |
2016 |
Journal: |
Hypertension |
Title: |
Impact of Angiotensin Type 1A Receptors in Principal Cells of the Collecting Duct on Blood Pressure and Hypertension. |
Volume: |
67 |
Issue: |
6 |
Pages: |
1291-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Alam G |
Year: |
2020 |
Journal: |
Pflugers Arch |
Title: |
Activation of farnesoid X receptor (FXR) induces crystallin zeta expression in mouse medullary collecting duct cells. |
Volume: |
472 |
Issue: |
11 |
Pages: |
1631-1641 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tinning AR |
Year: |
2016 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Vascular endothelial growth factor signaling is necessary for expansion of medullary microvessels during postnatal kidney development. |
Volume: |
311 |
Issue: |
3 |
Pages: |
F586-99 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xu S |
Year: |
2018 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Farnesoid X receptor is essential for the survival of renal medullary collecting duct cells under hypertonic stress. |
Volume: |
115 |
Issue: |
21 |
Pages: |
5600-5605 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(AQP2-cre)2Dek/? |
Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
225
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
216
|
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Rieg T |
Year: |
2010 |
Journal: |
J Am Soc Nephrol |
Title: |
Adenylate cyclase 6 determines cAMP formation and aquaporin-2 phosphorylation and trafficking in inner medulla. |
Volume: |
21 |
Issue: |
12 |
Pages: |
2059-68 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ma T |
Year: |
1997 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Cloning of a novel water and urea-permeable aquaporin from mouse expressed strongly in colon, placenta, liver, and heart. |
Volume: |
240 |
Issue: |
2 |
Pages: |
324-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chu JY |
Year: |
2007 |
Journal: |
Mol Cell Biol |
Title: |
Phenotypes developed in secretin receptor-null mice indicated a role for secretin in regulating renal water reabsorption. |
Volume: |
27 |
Issue: |
7 |
Pages: |
2499-511 |
|
•
•
•
•
•
|
Publication |
First Author: |
Koyama N |
Year: |
1998 |
Journal: |
Genomics |
Title: |
Cloning and functional expression of human aquaporin8 cDNA and analysis of its gene. |
Volume: |
54 |
Issue: |
1 |
Pages: |
169-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang MZ |
Year: |
2018 |
Journal: |
Hypertension |
Title: |
Renal Medullary Interstitial COX-2 (Cyclooxygenase-2) Is Essential in Preventing Salt-Sensitive Hypertension and Maintaining Renal Inner Medulla/Papilla Structural Integrity. |
Volume: |
72 |
Issue: |
5 |
Pages: |
1172-1179 |
|
•
•
•
•
•
|
Publication |
First Author: |
Klein JD |
Year: |
2002 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Impaired urine concentration and absence of tissue ACE: involvement of medullary transport proteins. |
Volume: |
283 |
Issue: |
3 |
Pages: |
F517-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xue J |
Year: |
2020 |
Journal: |
PLoS One |
Title: |
Genetic deletion of connexin 37 causes polyuria and polydipsia. |
Volume: |
15 |
Issue: |
12 |
Pages: |
e0244251 |
|
•
•
•
•
•
|
Publication |
First Author: |
Christensen BM |
Year: |
2011 |
Journal: |
J Am Soc Nephrol |
Title: |
alphaENaC-mediated lithium absorption promotes nephrogenic diabetes insipidus. |
Volume: |
22 |
Issue: |
2 |
Pages: |
253-61 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tomilin VN |
Year: |
2019 |
Journal: |
PLoS One |
Title: |
TRPC3 determines osmosensitive [Ca2+]i signaling in the collecting duct and contributes to urinary concentration. |
Volume: |
14 |
Issue: |
12 |
Pages: |
e0226381 |
|
•
•
•
•
•
|
Publication |
First Author: |
Poulsen SB |
Year: |
2017 |
Journal: |
JCI Insight |
Title: |
Role of adenylyl cyclase 6 in the development of lithium-induced nephrogenic diabetes insipidus. |
Volume: |
2 |
Issue: |
7 |
Pages: |
e91042 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ma T |
Year: |
2000 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Nephrogenic diabetes insipidus in mice lacking aquaporin-3 water channels. |
Volume: |
97 |
Issue: |
8 |
Pages: |
4386-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sim JH |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
Absence of PKC-alpha attenuates lithium-induced nephrogenic diabetes insipidus. |
Volume: |
9 |
Issue: |
7 |
Pages: |
e101753 |
|
•
•
•
•
•
|
Publication |
First Author: |
Thai TL |
Year: |
2012 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Lack of protein kinase C-α leads to impaired urine concentrating ability and decreased aquaporin-2 in angiotensin II-induced hypertension. |
Volume: |
303 |
Issue: |
1 |
Pages: |
F37-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ilori TO |
Year: |
2013 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Urine concentration in the diabetic mouse requires both urea and water transporters. |
Volume: |
304 |
Issue: |
1 |
Pages: |
F103-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Alsady M |
Year: |
2018 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Lithium induces aerobic glycolysis and glutaminolysis in collecting duct principal cells. |
Volume: |
314 |
Issue: |
2 |
Pages: |
F230-F239 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jia Z |
Year: |
2009 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Mice lacking mPGES-1 are resistant to lithium-induced polyuria. |
Volume: |
297 |
Issue: |
6 |
Pages: |
F1689-96 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nejsum LN |
Year: |
2002 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Functional requirement of aquaporin-5 in plasma membranes of sweat glands. |
Volume: |
99 |
Issue: |
1 |
Pages: |
511-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang F |
Year: |
2016 |
Journal: |
J Am Soc Nephrol |
Title: |
Antidiuretic Action of Collecting Duct (Pro)Renin Receptor Downstream of Vasopressin and PGE2 Receptor EP4. |
Volume: |
27 |
Issue: |
10 |
Pages: |
3022-3034 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sinke AP |
Year: |
2014 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Hydrochlorothiazide attenuates lithium-induced nephrogenic diabetes insipidus independently of the sodium-chloride cotransporter. |
Volume: |
306 |
Issue: |
5 |
Pages: |
F525-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bounoure L |
Year: |
2014 |
Journal: |
J Am Soc Nephrol |
Title: |
The role of the renal ammonia transporter Rhcg in metabolic responses to dietary protein. |
Volume: |
25 |
Issue: |
9 |
Pages: |
2040-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cai Q |
Year: |
2010 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Vasopressin increases expression of UT-A1, UT-A3, and ER chaperone GRP78 in the renal medulla of mice with a urinary concentrating defect. |
Volume: |
299 |
Issue: |
4 |
Pages: |
F712-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cai Q |
Year: |
2007 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Vasopressin receptor subtype 2 activation increases cell proliferation in the renal medulla of AQP1 null mice. |
Volume: |
293 |
Issue: |
6 |
Pages: |
F1858-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Breton S |
Year: |
1995 |
Journal: |
Am J Physiol |
Title: |
Depletion of intercalated cells from collecting ducts of carbonic anhydrase II-deficient (CAR2 null) mice. |
Volume: |
269 |
Issue: |
6 Pt 2 |
Pages: |
F761-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Evans LC |
Year: |
2012 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
A urine-concentrating defect in 11β-hydroxysteroid dehydrogenase type 2 null mice. |
Volume: |
303 |
Issue: |
4 |
Pages: |
F494-502 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang Y |
Year: |
2012 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Genetic deletion of the P2Y2 receptor offers significant resistance to development of lithium-induced polyuria accompanied by alterations in PGE2 signaling. |
Volume: |
302 |
Issue: |
1 |
Pages: |
F70-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang Y |
Year: |
2008 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Potential role of purinergic signaling in urinary concentration in inner medulla: insights from P2Y2 receptor gene knockout mice. |
Volume: |
295 |
Issue: |
6 |
Pages: |
F1715-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang X |
Year: |
2014 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Farnesoid X receptor (FXR) gene deficiency impairs urine concentration in mice. |
Volume: |
111 |
Issue: |
6 |
Pages: |
2277-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu Q |
Year: |
2018 |
Journal: |
J Am Soc Nephrol |
Title: |
CHIP Regulates Aquaporin-2 Quality Control and Body Water Homeostasis. |
Volume: |
29 |
Issue: |
3 |
Pages: |
936-948 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rahman SS |
Year: |
2017 |
Journal: |
FASEB J |
Title: |
EHD4 is a novel regulator of urinary water homeostasis. |
Volume: |
31 |
Issue: |
12 |
Pages: |
5217-5233 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nair AV |
Year: |
2019 |
Journal: |
PLoS One |
Title: |
Sex-dependent differences in water homeostasis in wild-type and V-ATPase B1-subunit deficient mice. |
Volume: |
14 |
Issue: |
8 |
Pages: |
e0219940 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xu J |
Year: |
2011 |
Journal: |
Kidney Int |
Title: |
Slc26a11, a chloride transporter, localizes with the vacuolar H(+)-ATPase of A-intercalated cells of the kidney. |
Volume: |
80 |
Issue: |
9 |
Pages: |
926-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rai T |
Year: |
2006 |
Journal: |
Am J Physiol Cell Physiol |
Title: |
Polarized trafficking of the aquaporin-3 water channel is mediated by an NH2-terminal sorting signal. |
Volume: |
290 |
Issue: |
1 |
Pages: |
C298-304 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang L |
Year: |
2006 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Galphaq-dependent signaling cascades stimulate water-seeking behavior. |
Volume: |
291 |
Issue: |
4 |
Pages: |
F781-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lam AK |
Year: |
2004 |
Journal: |
J Biol Chem |
Title: |
Osmotic response element-binding protein (OREBP) is an essential regulator of the urine concentrating mechanism. |
Volume: |
279 |
Issue: |
46 |
Pages: |
48048-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Habtemichael EN |
Year: |
2015 |
Journal: |
J Biol Chem |
Title: |
Coordinated Regulation of Vasopressin Inactivation and Glucose Uptake by Action of TUG Protein in Muscle. |
Volume: |
290 |
Issue: |
23 |
Pages: |
14454-61 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lu X |
Year: |
2016 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Soluble (pro)renin receptor via β-catenin enhances urine concentration capability as a target of liver X receptor. |
Volume: |
113 |
Issue: |
13 |
Pages: |
E1898-906 |
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•
•
•
•
•
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Publication |
First Author: |
Li S |
Year: |
2018 |
Journal: |
J Am Soc Nephrol |
Title: |
Bile Acid G Protein-Coupled Membrane Receptor TGR5 Modulates Aquaporin 2-Mediated Water Homeostasis. |
Volume: |
29 |
Issue: |
11 |
Pages: |
2658-2670 |
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•
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•
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Publication |
First Author: |
Petrillo F |
Year: |
2022 |
Journal: |
FASEB J |
Title: |
Genetic deletion of the nuclear factor of activated T cells 5 in collecting duct principal cells causes nephrogenic diabetes insipidus. |
Volume: |
36 |
Issue: |
11 |
Pages: |
e22583 |
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•
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•
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Publication |
First Author: |
Wang F |
Year: |
2019 |
Journal: |
JCI Insight |
Title: |
Site-1 protease-derived soluble (pro)renin receptor targets vasopressin receptor 2 to enhance urine concentrating capability. |
Volume: |
4 |
Issue: |
7 |
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•
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•
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•
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Publication |
First Author: |
Stegbauer J |
Year: |
2017 |
Journal: |
JCI Insight |
Title: |
Resistance to hypertension mediated by intercalated cells of the collecting duct. |
Volume: |
2 |
Issue: |
7 |
Pages: |
e92720 |
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Publication |
First Author: |
Stegbauer J |
Year: |
2011 |
Journal: |
J Am Soc Nephrol |
Title: |
AT1 receptors in the collecting duct directly modulate the concentration of urine. |
Volume: |
22 |
Issue: |
12 |
Pages: |
2237-46 |
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•
•
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•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
271
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
290
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
289
|
Fragment?: |
false |
|
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•
•
•
•
|
Publication |
First Author: |
Sproul A |
Year: |
2011 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
N-methyl-D-aspartate receptor subunit NR3a expression and function in principal cells of the collecting duct. |
Volume: |
301 |
Issue: |
1 |
Pages: |
F44-54 |
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•
•
•
•
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Publication |
First Author: |
Nørregaard R |
Year: |
2011 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
COX-2 disruption leads to increased central vasopressin stores and impaired urine concentrating ability in mice. |
Volume: |
301 |
Issue: |
6 |
Pages: |
F1303-13 |
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•
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Publication |
First Author: |
Wall SM |
Year: |
2006 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Hypotension in NKCC1 null mice: role of the kidneys. |
Volume: |
290 |
Issue: |
2 |
Pages: |
F409-16 |
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•
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•
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Publication |
First Author: |
Jia Z |
Year: |
2012 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
mPGES-1 deletion potentiates urine concentrating capability after water deprivation. |
Volume: |
302 |
Issue: |
8 |
Pages: |
F1005-12 |
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•
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Publication |
First Author: |
Wang H |
Year: |
2019 |
Journal: |
Physiol Rep |
Title: |
Sickle cell disease up-regulates vasopressin, aquaporin 2, urea transporter A1, Na-K-Cl cotransporter 2, and epithelial Na channels in the mouse kidney medulla despite compromising urinary concentration ability. |
Volume: |
7 |
Issue: |
8 |
Pages: |
e14066 |
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Publication |
First Author: |
Wang W |
Year: |
2008 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Role of AQP1 in endotoxemia-induced acute kidney injury. |
Volume: |
294 |
Issue: |
6 |
Pages: |
F1473-80 |
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Publication |
First Author: |
Ahrabi AK |
Year: |
2007 |
Journal: |
J Am Soc Nephrol |
Title: |
PKD1 haploinsufficiency causes a syndrome of inappropriate antidiuresis in mice. |
Volume: |
18 |
Issue: |
6 |
Pages: |
1740-53 |
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•
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Publication |
First Author: |
Li XC |
Year: |
2009 |
Journal: |
Kidney Int |
Title: |
AT1a receptor knockout in mice impairs urine concentration by reducing basal vasopressin levels and its receptor signaling proteins in the inner medulla. |
Volume: |
76 |
Issue: |
2 |
Pages: |
169-77 |
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Publication |
First Author: |
Li XC |
Year: |
2012 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
AT1a receptor signaling is required for basal and water deprivation-induced urine concentration in AT1a receptor-deficient mice. |
Volume: |
303 |
Issue: |
5 |
Pages: |
F746-56 |
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•
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Publication |
First Author: |
Cai Q |
Year: |
2006 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Effects of water restriction on gene expression in mouse renal medulla: identification of 3betaHSD4 as a collecting duct protein. |
Volume: |
291 |
Issue: |
1 |
Pages: |
F218-24 |
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•
•
•
•
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Publication |
First Author: |
Zhang Y |
Year: |
2012 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Defective renal water handling in transgenic mice over-expressing human CD39/NTPDase1. |
Volume: |
303 |
Issue: |
3 |
Pages: |
F420-30 |
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•
•
•
•
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Publication |
First Author: |
Street JM |
Year: |
2011 |
Journal: |
J Physiol |
Title: |
Exosomal transmission of functional aquaporin 2 in kidney cortical collecting duct cells. |
Volume: |
589 |
Issue: |
Pt 24 |
Pages: |
6119-27 |
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•
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Publication |
First Author: |
Kortenoeven ML |
Year: |
2014 |
Journal: |
Biochim Biophys Acta |
Title: |
Renal aquaporins and water balance disorders. |
Volume: |
1840 |
Issue: |
5 |
Pages: |
1533-49 |
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•
•
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•
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Publication |
First Author: |
Zhang Y |
Year: |
2018 |
Journal: |
Front Physiol |
Title: |
Genetic Deletion of P2Y2 Receptor Offers Long-Term (5 Months) Protection Against Lithium-Induced Polyuria, Natriuresis, Kaliuresis, and Collecting Duct Remodeling and Cell Proliferation. |
Volume: |
9 |
|
Pages: |
1765 |
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•
•
•
•
•
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Publication |
First Author: |
Gorelick DA |
Year: |
2006 |
Journal: |
BMC Biochem |
Title: |
Aquaporin-11: a channel protein lacking apparent transport function expressed in brain. |
Volume: |
7 |
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Pages: |
14 |
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•
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•
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