Primary Identifier | MGI:5789897 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Hotair |
Transmission | Germline | Strain of Origin | (C57BL/6NTac x 129S6/SvEvTac)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The targeting vector was designed to insert a loxP site 5' of exon 1 and a loxP-flanked neomycin cassette in intron 2. Exons 1 and 2 comprise the full length gene. Cre-mediated recombination removed the floxed region. Quantitative RT-PCR analysis did not detect mRNA in homozygous mutant mice. |