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Protein Coding Gene : Fev FEV transcription factor, ETS family member

Primary Identifier  MGI:2449712 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  260298
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within maternal behavior; neuron differentiation; and positive regulation of gene expression. Located in nucleus. Is expressed in several structures, including aorta-gonad-mesonephros; liver; and nervous system. Orthologous to human FEV (FEV transcription factor, ETS family member).
PHENOTYPE: Homozygous inactivation of this gene leads to partial lethality within the first week of life, causes impaired serotonergic neuron development, and results in increased anxiety-like and aggressive behavior in adulthood. [provided by MGI curators]
  • synonyms:
  • FEV transcription factor, ETS family member,
  • MGD-MRK-19673,
  • MGI:102766,
  • plasmacytoma expressed gene 1,
  • mPet-1,
  • Fev,
  • Pex1,
  • Pet1,
  • plasmacytoma expressed transcript 1

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

8 Driver For