| Primary Identifier | MGI:891963 | Organism | mouse, laboratory |
| Chromosome | 12 | NCBI Gene Number | 22630 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables protein domain specific binding activity. Acts upstream of or within protein targeting and small GTPase-mediated signal transduction. Predicted to be located in cytosol. Predicted to be part of protein-containing complex. Predicted to be active in cytoplasm and synapse. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human YWHAQ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta). PHENOTYPE: Embryos homozygous for a gene trap allele are developmentally delayed and die by E14 with no specific cardiac defects; however, heterozygotes develop larger myocardial infarctions with increased post-infarction cardiac remodeling while cultured cardiomyocytes are sensitized to proapoptotic stimuli. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
