| First Author | Spanopoulou E | Year | 1988 |
| Journal | Mol Cell Biol | Volume | 8 |
| Issue | 9 | Pages | 3847-56 |
| PubMed ID | 2906111 | Mgi Jnum | J:9601 |
| Mgi Id | MGI:58060 | Doi | 10.1128/mcb.8.9.3847 |
| Citation | Spanopoulou E, et al. (1988) Transcriptional unit of the murine Thy-1 gene: different distribution of transcription initiation sites in brain. Mol Cell Biol 8(9):3847-56 |
| abstractText | Structural analysis of the mouse Thy-1.2 gene has shown that the major promoter of the gene is characterized by a tissue-specific DNase I-hypersensitive site and is located within a methylation-free island. The gene is regulated at the transcriptional level, and steady-state mRNA analysis reveals that the previously reported exon Ib contributes at most 5% of the total mRNA. The major promoter uses several transcription initiation sites within a region of 100 base pairs. The frequency of usage of these sites in brain is markedly different from that in other tissues. |
