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Allele : Homer1<tm2Mhd> homer scaffolding protein 1; targeted mutation 2, Marlin H Dehoff

Primary Identifier  MGI:5086112 Allele Type  Targeted
Attribute String  Inserted expressed sequence, Modified isoform(s) Gene  Homer1
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1
Is Recombinase  false Is Wild Type  false
molecularNote  A rat cDNA containing exons 6 through 10, which encodes the 'c' isoform, followed by a floxed neo cassette was inserted in frame with exon 5 and replaced alternative exons for the immediate-early isoforms 'a' and 'Ania3'. The absence of the 'a' isoform was confirmed by western blot analysis following induction of expression by maximal electroconvulsive seizure. Expression of the 'b' and 'c' isoform is normal.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Homer1a<->,
  • H1a<->,
  • Homer1a<->,
  • H1a<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

11 Publication categories

Trail: Allele