| Primary Identifier | MGI:1347345 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 26556 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable several functions, including scaffold protein binding activity; transmembrane transporter binding activity; and type 5 metabotropic glutamate receptor binding activity. Predicted to be a structural constituent of postsynapse. Involved in regulation of calcium ion import and regulation of store-operated calcium entry. Acts upstream of or within several processes, including behavioral response to cocaine; skeletal muscle contraction; and skeletal muscle fiber development. Located in several cellular components, including apical part of cell; myofibril; and postsynaptic density. Is active in glutamatergic synapse and postsynaptic cytosol. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human HOMER1 (homer scaffold protein 1). PHENOTYPE: Homozygous mutants exhibit an increase in spontaneous calcium influx in pancreatic acinar cells. Mice homozygous for a knock-out allele exhibit decreased response to formalin-induced pain. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
