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Allele : Abca7<em2Adiuj> ATP-binding cassette, sub-family A member 7; endonuclease-mediated mutation 2, MODEL-AD Center
Primary Identifier  MGI:6164020 Allele Type  Endonuclease-mediated
Attribute String  Humanized sequence Gene  Abca7
Strain of Origin  B6(SJL)-Apoe<tm1.1(APOE*4)Adiuj> Trem2<em1Adiuj>/J Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 genome editing methodology is used to introduce an alanine to glycine at position 1527 in exon 33.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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