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Allele : Psap<tm1Juma> prosaposin; targeted mutation 1, Junko Matsuda

Primary Identifier  MGI:3521746 Allele Type  Targeted
Attribute String  Null/knockout Gene  Psap
Transmission  Germline Strain of Origin  129S/SvEv
Is Recombinase  false Is Wild Type  false
molecularNote  A C509S mutation was introduced to exon 13 to destroy one of the three disulfide bridges in the saposin D domain. A neo was removed from intron 14 via transient cre expression. RT-PCR indicated an absence of transcript in mutant mouse brains.
  • mutations:
  • Insertion
  • synonyms:
  • sap D<->,
  • sap D<->,
  • D<->,
  • D<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

7 Publication categories

Trail: Allele