Primary Identifier | MGI:3521746 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Psap |
Transmission | Germline | Strain of Origin | 129S/SvEv |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A C509S mutation was introduced to exon 13 to destroy one of the three disulfide bridges in the saposin D domain. A neo was removed from intron 14 via transient cre expression. RT-PCR indicated an absence of transcript in mutant mouse brains. |