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Protein Coding Gene : Mfsd12 major facilitator superfamily domain containing 12
Primary Identifier  MGI:3604804 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  73822
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable cysteine transmembrane transporter activity. Involved in negative regulation of melanin biosynthetic process and pigment metabolic process involved in pigmentation. Acts upstream of or within hair follicle development and pigmentation. Predicted to be located in late endosome; lysosome; and melanosome. Predicted to be active in plasma membrane. Is expressed in thymus primordium. Orthologous to human MFSD12 (major facilitator superfamily domain containing 12).
PHENOTYPE: Mice homozygous for a null allele exhibit a grey (grizzled) coat. [provided by MGI curators]
  • synonyms:
  • major facilitator superfamily domain containing 12,
  • F630110N24Rik,
  • Wdt1,
  • grizzled,
  • MGI:95803,
  • MGD-MRK-10239,
  • RIKEN cDNA F630110N24 gene,
  • Mfsd12,
  • gr
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1 Involved In Mutations

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