Primary Identifier | MGI:2685725 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 380702 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables PDZ domain binding activity and ionotropic glutamate receptor binding activity. Involved in several processes, including excitatory chemical synaptic transmission; negative regulation of canonical Wnt signaling pathway; and postsynaptic neurotransmitter receptor diffusion trapping. Located in asymmetric, glutamatergic, excitatory synapse and postsynaptic density. Part of AMPA glutamate receptor complex. Is active in glutamatergic synapse and postsynaptic density membrane. Is expressed in central nervous system and testis. Orthologous to human SHISA6 (shisa family member 6). PHENOTYPE: Homozygous knockout has no gross phenotypic effect. [provided by MGI curators] |